SGI-1027
SGI-1027 (DNA Methyltransferase Inhibitor II) is a DNMT inhibitor with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B in cell-free assays, respectively. SGI‑1027 induces apoptosis.
| Trivial name | DNA Methyltransferase Inhibitor II |
| Catalog Number | S7276 |
| Molecular Formula | C27H23N7O |
| CAS# | 1020149-73-8 |
| Inchi | InChI=1S/C27H23N7O/c1-17-16-25(34-27(28)30-17)32-20-10-12-21(13-11-20)33-26(35)18-6-8-19(9-7-18)31-24-14-15-29-23-5-3-2-4-22(23)24/h2-16H,1H3,(H,29,31)(H,33,35)(H3,28,30,32,34) |
| Inchi Key | QSYLKMKIVWJAAK-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC(=N1)N)NC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)NC4=CC=NC5=CC=CC=C54 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/sgi-1027.html |
| Additional Information | https://file.selleck.cn/downloads/struct/SGI-1027-chemical-structure-s7276.gif |