Regorafenib (BAY-734506) Monohydrate
Regorafenib (BAY-734506, Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate) Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, Kit (c-Kit), RET (c-RET), RAF-1, B-RAF and B-RAF(V600E) respectively.
| Trivial name | Fluoro-sorafenib, Resihance, Stivarga, regorafaenib monohydrate |
| Catalog Number | S5077 |
| Molecular Formula | C20H18O8 |
| CAS# | 1019206-88-2 |
| Inchi | InChI=1S/C20H18O8/c1-22-13-5-10(6-14(23-2)18(13)24-3)11-8-26-12-7-15-19(28-9-27-15)20(25-4)16(12)17(11)21/h5-8H,9H2,1-4H3 |
| Inchi Key | RISXUTCDCPHJFQ-UHFFFAOYSA-N |
| SMILES | COC1=CC(=CC(=C1OC)OC)C2=COC3=CC4=C(C(=C3C2=O)OC)OCO4 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/regorafenib-monohydrate.html |
| Additional Information | https://file.selleck.cn/downloads/struct/regorafenib-monohydrate-chemical-structure-s5077.gif |