Avadomide (CC-122)
Avadomide (CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN.
| Trivial name | N/A |
| Catalog Number | S7892 |
| Molecular Formula | C14H14N4O3 |
| CAS# | 1015474-32-4 |
| Inchi | InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20) |
| Inchi Key | RSNPAKAFCAAMBH-UHFFFAOYSA-N |
| SMILES | CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/cc-122.html |
| Additional Information | https://file.selleck.cn/downloads/struct/cc-122-chemical-structure-s7892.gif |