CUDC-101
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1194 |
| Molecular Formula | C24H26N4O4 |
| CAS# | 1012054-59-9 |
| Inchi | InChI=1S/C24H26N4O4/c1-3-17-9-8-10-18(13-17)27-24-19-14-22(21(31-2)15-20(19)25-16-26-24)32-12-7-5-4-6-11-23(29)28-30/h1,8-10,13-16,30H,4-7,11-12H2,2H3,(H,28,29)(H,25,26,27) |
| Inchi Key | PLIVFNIUGLLCEK-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)N=CN=C2NC3=CC=CC(=C3)C#C)OCCCCCCC(=O)NO |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/CUDC-101.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CUDC-101-chemical-structure-S1194.gif |