CUDC-101
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
Trivial name | N/A |
Catalog Number | S1194 |
Molecular Formula | C19H23O10PS |
CAS# | 1012054-59-9 |
Inchi | InChI=1S/C19H23O10PS/c1-25-14-10-17(27-3)15(18(11-14)28-4)7-8-31(23,24)12-13-5-6-16(26-2)19(9-13)29-30(20,21)22/h5-11H,12H2,1-4H3,(H2,20,21,22)/b8-7+ |
Inchi Key | LXENKEWVEVKKGV-BQYQJAHWSA-N |
SMILES | COC1=C(C=C(C=C1)CS(=O)(=O)C=CC2=C(C=C(C=C2OC)OC)OC)OP(=O)(O)O |
Size | 10mM/1mL |
Supplier Page | http://www.selleckchem.com/products/CUDC-101.html |
Additional Information | https://file.selleck.cn/downloads/struct/CUDC-101-chemical-structure-S1194.gif |