CUDC-101
CUDC-101 is a potent multi-targeted inhibitor against HDAC, EGFR and HER2 with IC50 of 4.4 nM, 2.4 nM, and 15.7 nM, and inhibits class I/II HDACs, but not class III, Sir-type HDACs. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1194 |
| Molecular Formula | C18H25NO3Si |
| CAS# | 1012054-59-9 |
| Inchi | InChI=1S/C18H25NO3Si/c1-18(2,3)23(4,5)22-12-8-9-15-14(11-12)13-7-6-10-19-16(13)17(20)21-15/h8-9,11,19H,6-7,10H2,1-5H3 |
| Inchi Key | UNMWMPXUIXEQJZ-UHFFFAOYSA-N |
| SMILES | CC(C)(C)[Si](C)(C)OC1=CC2=C(C=C1)OC(=O)C3=C2CCCN3 |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/CUDC-101.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CUDC-101-chemical-structure-S1194.gif |