Silmitasertib (CX-4945)

Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay). Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.

Price Not Available 5mg Silmitasertib (CX-4945) Supplier Page
Trivial name N/A
Catalog Number S2248
Molecular Formula C19H12ClN3O2
CAS# 1009820-21-6
Inchi InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)
Inchi Key MUOKSQABCJCOPU-UHFFFAOYSA-N
SMILES C1=CC(=CC(=C1)Cl)NC2=NC3=C(C=CC(=C3)C(=O)O)C4=C2C=CN=C4
Size 5mg
Supplier Page http://www.selleckchem.com/products/cx-4945-silmitasertib.html
Additional Information https://file.selleck.cn/downloads/struct/CX-4945-chemical-structure-S2248.gif