Vistusertib (AZD2014)

Vistusertib (AZD2014) is a novel mTOR inhibitor with IC50 of 2.8 nM in a cell-free assay; highly selective against multiple PI3K isoforms (α/β/γ/δ). AZD2014 showed no or weak binding to the majority of kinases when tested at 1 μM. AZD2014 induces proliferation suppression, apoptosis, cell cycle arrest, and autophagy in HCC cells with antitumor activity.

Price Not Available 5mg Vistusertib (AZD2014) Supplier Page

Trivial name	N/A
Catalog Number	S2783
Molecular Formula	C26H34O7
CAS#	1009298-59-2
Inchi	InChI=1S/C26H34O7/c1-18(2)13-14-20-25(3,33-20)24-23(30-4)19(15-16-26(24)17-31-26)32-22(29)12-10-8-6-5-7-9-11-21(27)28/h5-13,19-20,23-24H,14-17H2,1-4H3,(H,27,28)/b7-5+,8-6+,11-9+,12-10+/t19-,20-,23-,24 -,25+,26+/m1/s1
Inchi Key	NGGMYCMLYOUNGM-CSDLUJIJSA-N
SMILES	CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC=CC=CC=CC(=O)O)OC)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/azd2014.html
Additional Information	https://file.selleck.cn/downloads/struct/AZD2014-chemical-structure-s2783.gif