AZD8055
AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. AZD8055 induces caspase-dependent apoptosis and also induces autophagy. Phase 1.
| Trivial name | N/A |
| Catalog Number | S1555 |
| Molecular Formula | C21H19F2NO3 |
| CAS# | 1009298-09-2 |
| SMILES | CCOC1=CC=C(OC2=CC=C(OCC3=C(F)C=CC(=C3)F)C=C2)C(=C1)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/AZD8055.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD8055-chemical-structure-S1555.gif |