CH5132799
CH5132799 (MEN1611, PA799) inhibits class I PI3Ks, particularly PI3Kα with IC50 of 14 nM; less potent to PI3Kβδγ, while sensitive in PIK3CA mutations cell lines. Phase 1.
| Trivial name | MEN1611, PA799 |
| Catalog Number | S2699 |
| Molecular Formula | C18H13ClF6N2O3 |
| CAS# | 1007207-67-1 |
| Inchi | InChI=1S/C18H13ClF6N2O3/c1-9(15(28)26-14-4-2-13(19)3-5-14)30-27-16(29)10-6-11(17(20,21)22)8-12(7-10)18(23,24)25/h2-9H,1H3,(H,26,28)(H,27,29) |
| Inchi Key | DSMXVSGJIDFLKP-UHFFFAOYSA-N |
| SMILES | CC(C(=O)NC1=CC=C(C=C1)Cl)ONC(=O)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/ch5132799.html |
| Additional Information | https://file.selleck.cn/downloads/struct/CH5132799-chemical-structure-s2699.gif |