MK-8033
MK-8033 is an orally active ATP competitive c-Met/Ron dual inhibitor (IC50s: 1 nM (c-Met),7 nM (Ron)), with preferential binding to the activated kinase conformation. MK-8033 can be used in the research of cancers, such as breast and bladder cancers, non-small cell lung cancers (NSCLCs).
| Catalog Number | E7687 |
| Molecular Formula | C9H12ClN5O |
| CAS# | 1001917-37-8 |
| Inchi | InChI=1S/C9H12ClN5O/c1-5-13-7(10)6(8(14-5)16-2)15-9-11-3-4-12-9/h3-4H2,1-2H3,(H2,11,12,15) |
| Inchi Key | WPNJAUFVNXKLIM-UHFFFAOYSA-N |
| SMILES | CC1=NC(=C(C(=N1)Cl)NC2=NCCN2)OC |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/mk-8033.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7687-mk-8033-chemical-structure-tube.png |