Ipatasertib (GDC-0068)

Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.

Price Not Available 5mg Ipatasertib (GDC-0068) Supplier Page
Trivial name RG7440
Catalog Number S2808
Molecular Formula C24H32ClN5O2
CAS# 1001264-89-6
Inchi InChI=1S/C24H32ClN5O2/c1-15(2)26-13-19(17-4-6-18(25)7-5-17)24(32)30-10-8-29(9-11-30)23-21-16(3)12-20(31)22(21)27-14-28-23/h4-7,14-16,19-20,26,31H,8-13H2,1-3H3/t16-,19-,20-/m1/s1
Inchi Key GRZXWCHAXNAUHY-NSISKUIASA-N
SMILES CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
Size 5mg
Supplier Page http://www.selleckchem.com/products/gdc-0068.html
Additional Information https://file.selleck.cn/downloads/struct/GDC-0068-chemical-structure-s2808.gif