Ipatasertib (GDC-0068)

Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.

Price Not Available 10mM/1mL Ipatasertib (GDC-0068) Supplier Page
Trivial name RG7440
Catalog Number S2808
Molecular Formula C20H23N2O5S.Na
CAS# 1001264-89-6
Inchi InChI=1S/C20H24N2O5S.Na/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18;/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23);/q;+1/p-1
Inchi Key LFQQNXFKPNZRFT-UHFFFAOYSA-M
SMILES CC(C)(C1=COC(=C1)S(=O)(=O)[N-]C(=O)NC2=C3CCCC3=CC4=C2CCC4)O.[Na+]
Size 10mM/1mL
Supplier Page http://www.selleckchem.com/products/gdc-0068.html
Additional Information https://file.selleck.cn/downloads/struct/GDC-0068-chemical-structure-s2808.gif