Pentamidine
Pentamidine (MP-601205) is an aromatic diamidine drug, an antagonist of TLR4.It also inhibits PI3K/AKT signaling pathway and reduce the expression of MMP-2 and MMP-9. It exhibits anti- protozoal, anti-inflammatory, and anti-tumor activities and is used as an agent for treating African trypanosomiasis, antimony resistant leishmaniasis and Pneumocystis carinii pneumonia.
| Trivial name | MP-601205 |
| Catalog Number | E4864 |
| Molecular Formula | C28H24FN3O5 |
| CAS# | 100-33-4 |
| Inchi | InChI=1S/C28H24FN3O5/c1-35-24-15-21-22(16-25(24)36-2)30-14-11-23(21)37-20-9-7-19(8-10-20)32-27(34)28(12-13-28)26(33)31-18-5-3-17(29)4-6-18/h3-11,14-16H,12-13H2,1-2H3,(H,31,33)(H,32,34) |
| Inchi Key | ONIQOQHATWINJY-UHFFFAOYSA-N |
| SMILES | COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/pentamidine.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4864-Pentamidine-chemical-structure.png |