BSTFA-TMCS
25mg
| Purity Not Available
Selleck Chemicals
BSTFA-TMCS is used as a derivatizing agent in chromatography. It functions as a silylation reagent without additional solvents. The combination of BSTFA and TMCS is the preferred reagent for trimethylsilylation of alcohols, alkaloids, amines, biogenic amines, carboxylic acids, phenols, and steroids.
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BT2
5mg
| Purity Not Available
Selleck Chemicals
BT2
25mg
| Purity Not Available
Selleck Chemicals
BTB-1
5mg
| Purity Not Available
Selleck Chemicals
BTB-1
25mg
| Purity Not Available
Selleck Chemicals
BTB06584
10mg
| Purity Not Available
Selleck Chemicals
BTdCPU
5mg
| Purity Not Available
Selleck Chemicals
BTdCPU is a potent activator of heme regulated inhibitor kinase (HRI), one of eukaryotic translation initiation factor 2α kinases (eIF2α-kinases).
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BTdCPU
25mg
| Purity Not Available
Selleck Chemicals
BTdCPU is a potent activator of heme regulated inhibitor kinase (HRI), one of eukaryotic translation initiation factor 2α kinases (eIF2α-kinases).
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BTK IN-1
5mg
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
BTK inhibitor 1 (compound 27) is an inhibitor of BTK with an IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with an IC50 of 2 nM.
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Selleck Chemicals
BTR-1
5mg
| Purity Not Available
Selleck Chemicals
BTR-1 induces cytotoxicity in a time- and concentration-dependent manner on leukemia cell line CEM. BTR-1 affects DNA replication by inducing a block at S phase and leads to activation of apoptosis to induce cell death.
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BTSA1
2mg
| Purity Not Available
Selleck Chemicals
BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
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BTSA1
5mg
| Purity Not Available
Selleck Chemicals
BTSA1 is a pharmacologically optimized BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells.
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BTYNB
25mg
| Purity Not Available
Selleck Chemicals
BTYNB (BTYNB IMP1 Inhibitor, MDK6620) is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. BTYNB downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). BTYNB disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association.
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BTYNB
100mg
| Purity Not Available
Selleck Chemicals
BTYNB (BTYNB IMP1 Inhibitor, MDK6620) is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. BTYNB downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). BTYNB disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association.
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BTYNB
1g
| Purity Not Available
Selleck Chemicals
BTYNB (BTYNB IMP1 Inhibitor, MDK6620) is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. BTYNB downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa B (NF-κB). BTYNB disrupts this enhancer function by impairing IGF2 mRNA-binding protein 1 (IGF2BP1)-RNA association.
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BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2′-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis.
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BTZO-1
25mg
| Purity Not Available
Selleck Chemicals
BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro.
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BTZO-1
5mg
| Purity Not Available
Selleck Chemicals
BTZO-1 binds to macrophage migration inhibitory factor (MIF) with Kd of 68.6 nM. BTZO-1 activats antioxidant response element (ARE)-mediated gene expression and suppresses oxidative stress-induced cardiomyocyte apoptosis in vitro.
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Bucetin
100mg
| Purity Not Available
Selleck Chemicals
Buclizine HCl
50mg
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
Buddleja Officinalis Extract is drawed from Buddleja officinalis flower, which is reportedly effective in treating inflammation, conjunctival hypertension, and headache in traditional oriental herbal medicine.
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Buddlejasaponin IVb (Saikosaponin 1b), a major component of Pleurospermum kamtschaticum, exerts anti-inflammatory and cytotoxic effects against cancer cells.
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Budesonide
50mg
| Purity Not Available
Selleck Chemicals
Budesonide
1g
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
Budigalimab (Anti-PDCD1 / PD-1 / CD279) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. It can be used in the treatment of advanced solid tumors. MW :145.84 KD.
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Selleck Chemicals
Budigalimab (Anti-PDCD1 / PD-1 / CD279) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. It can be used in the treatment of advanced solid tumors. MW :145.84 KD.
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Selleck Chemicals
Budigalimab (Anti-PDCD1 / PD-1 / CD279) is a humanized IgG1 monoclonal antibody targeting programmed cell death 1 (PD-1) receptor. It can be used in the treatment of advanced solid tumors. MW :145.84 KD.
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Bufalin
25mg
| Purity Not Available
Selleck Chemicals
Bufalin (BF) is a potent inhibitor of steroid receptor coactivator SRC-3, SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1, α2 and α3 of Na+/K+-ATPase with Kd of 42.5 nM, 45 nM and 40 nM, respectively. Bufalin is a major digoxin-like immunoreactive component isolated from the Chinese medicine Chan Su with anti-cancer activity.
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Bufalin
5mg
| Purity Not Available
Selleck Chemicals
Bufalin (BF) is a potent inhibitor of steroid receptor coactivator SRC-3, SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1, α2 and α3 of Na+/K+-ATPase with Kd of 42.5 nM, 45 nM and 40 nM, respectively. Bufalin is a major digoxin-like immunoreactive component isolated from the Chinese medicine Chan Su with anti-cancer activity.
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Bufalin
10mM/1mL
| Purity Not Available
Selleck Chemicals
Bufalin (BF) is a potent inhibitor of steroid receptor coactivator SRC-3, SRC-1 and Na+/K+-ATPase. Bufalin binds to the subunit α1, α2 and α3 of Na+/K+-ATPase with Kd of 42.5 nM, 45 nM and 40 nM, respectively. Bufalin is a major digoxin-like immunoreactive component isolated from the Chinese medicine Chan Su with anti-cancer activity.
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Bufexamac
1g
| Purity Not Available
Selleck Chemicals
Bufexamac
50mg
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
Selleck Chemicals
Buflomedil HCl(NSC 759291) is a vasodilator used to treat claudication or the symptoms of peripheral arterial disease; A nonselective alpha adrenergic receptor inhibitor.
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Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport.
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Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport.
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Selleck Chemicals
Bulevirtide (Myrcludex B) is a sodium-taurocholate co-transporting polypeptide (NTCP) receptor inhibitor with IC50 of ∼80 pM and inactivates NTCP function at concentrations far below those required to block bile salt transport.
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Bulleyaconi cine A (Bulleyaconitine A, BLA) is an active ingredient of Aconitum bulleyanum plants and classified as an “aconitine-like” alkaloid. It is a potent use-dependent blocker for both Nav1.7 and Nav1.8 Na+ currents.
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Bumetanide
50mg
| Purity Not Available
Selleck Chemicals
Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.
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Bumetanide
1g
| Purity Not Available
Selleck Chemicals
Bumetanide is a loop diuretic of the sulfamyl category to treat heart failure. Bumetanide is a selective Na+-K+-Cl- cotransporter 1 (NKCC1) inhibitor, weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively.
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Bunge Auriculate Root (Baishouwu) Extract is extracted from the root tubers of Cynanchum auriculatum, Cynanchum bungei, and Cynanchum wilfordii in China, which is a famous tonic drug in TCM and known for its functions in enriching vital essence and enhancing immunity.
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Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
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Selleck Chemicals
Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
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Selleck Chemicals
Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
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Selleck Chemicals
Buparlisib (BKM120, NVP-BKM120) is a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM in cell-free assays, respectively. Reduced potency against VPS34, mTOR, DNAPK, with little activity to PI4Kβ. Buparlisib induces apoptosis. Phase 2.
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Buparvaquone
25mg
| Purity Not Available
Selleck Chemicals
Buparvaquone (Butalex) is a second-generation hydroxynaphthoquinone related to parvaquone, with novel features that make it a promising compound for the therapy and prophylaxis of all forms of theileriosis.
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Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.
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Bupivacaine HCl
10mM/1mL
| Purity Not Available
Selleck Chemicals
Bupivacaine HCl binds to the intracellular portion of voltage-gated sodium channels and blocks sodium influx into nerve cells, used for treating cardiac arrhythmias.
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