Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteBemarituzumab (Anti-FGFR2 / CD332) is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research. MW: 145.24 KD.
More Information Supplier PageBemarituzumab (Anti-FGFR2 / CD332) is a first-in-class, humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has the potential for cancer research. MW: 145.24 KD.
More Information Supplier PageBemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
More Information Supplier PageBemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
More Information Supplier PageBemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
More Information Supplier PageBemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
More Information Supplier PageBemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective).
More Information Supplier PageBemegride(Bemegrid,3-Ethyl-3-methylglutarimide) is a central nervous system stimulant and antidote for barbiturate poisoning.
More Information Supplier PageBemnifosbuvir Hemisulfate (AT-527, RG-6422, RO 7496998) is a hemi-sulfate salt of AT-511. AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0.47 μM.
More Information Supplier PageBemnifosbuvir Hemisulfate (AT-527, RG-6422, RO 7496998) is a hemi-sulfate salt of AT-511. AT-511 is a potent inhibitor of SARS-CoV-2 with an EC90 of 0.47 μM.
More Information Supplier PageBempedoic acid (ETC-1002),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
More Information Supplier PageBempedoic acid (ETC-1002),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
More Information Supplier PageBempedoic acid (ETC-1002),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
More Information Supplier PageBempedoic acid (ETC-1002),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
More Information Supplier PageBempedoic acid (ETC-1002),also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).
More Information Supplier PageBenactyzine hydrochloride is a centrally acting muscarinic antagonist. It is used as an antidepressant in the treatment of depression and associated anxiety.
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Benazepril is used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure. Benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.
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Benazepril HCl (CGS 14824A) is a novel angiotensin I converting enzyme inhibitor, used primarily in treatment of hypertension.
More Information Supplier PageBendamustine is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin’s lymphoma.
More Information Supplier PageBendamustine is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin’s lymphoma.
More Information Supplier PageBendamustine is a nitrogen mustard drug used in the treatment of chronic lymphocytic leukemia (CLL), multiple myeloma, and non-Hodgkin’s lymphoma.
More Information Supplier PageBendamustine HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.
More Information Supplier PageBendamustine HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.
More Information Supplier PageBendamustine HCl is a DNA-damaging agent with IC50 of 50 μM in cell-free assay.
More Information Supplier PageBendazac (bendazolic acid, AF-983) is a non-steroidal anti-inflammatory drug that delays the cataractogenic process. It may act by preventing protein denaturation.
More Information Supplier PageBendazac L-lysine has a protective effect against lens protein denaturation both in vitro and in vivo. It is also a nonsteroidal anti-inflammatory drug (NSAID) used for joint and muscular pain.
More Information Supplier PageBendazol (2-Benzylbenzimidazole, Dibazol, Dibazole, Bendazole, Tromasedan) is a hypotensive drug that enhances NO synthase activity in renal glomeruli and collecting tubules. Bendazol inhibits the progression of form-deprivation myopia (FDM) and suppresses the upregulation of HIF-1α.
More Information Supplier PageBenfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1) and has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2. Benfotiamine suppresses oxidative stress-induced NF-κB activation and prevents the bacterial endotoxin-induced inflammation.
More Information Supplier PageBenfotiamine (S-Benzoylthiamine O-monophosphate) is a synthetic S-acyl derivative of thiamine (vitamin B1) and has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2. Benfotiamine suppresses oxidative stress-induced NF-κB activation and prevents the bacterial endotoxin-induced inflammation.
More Information Supplier PageBenidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.
More Information Supplier PageBenidipine HCl (KW-3049,(±)- Benidipine) is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.
More Information Supplier PageBenorylate (Benorilate, Benoral, Benortan) is the esterification product of paracetamol and acetylsalicylic acid with anti-inflammatory, analgesic and antipyretic properties.
More Information Supplier PageBenpyrine racemate ((Rac)-Benpyrine) is a potent, highly specific and orally active inhibitor of TNF-α and attenuates TNF-α-induced inflammation, thereby reducing liver and lung injury.
More Information Supplier PageBenpyrine racemate ((Rac)-Benpyrine) is a potent, highly specific and orally active inhibitor of TNF-α and attenuates TNF-α-induced inflammation, thereby reducing liver and lung injury.
More Information Supplier PageBenralizumab (Anti-IL-5Ra/ CD125) is an afucosylated, humanized monoclonal antibody against the alpha chain of the interleukin-5 receptor (IL-5Ra) with potential anti-asthmatic activity. MW: 145.5 kD.
More Information Supplier PageBenralizumab (Anti-IL-5Ra/ CD125) is an afucosylated, humanized monoclonal antibody against the alpha chain of the interleukin-5 receptor (IL-5Ra) with potential anti-asthmatic activity. MW: 145.5 kD.
More Information Supplier PageBenralizumab (Anti-IL-5Ra/ CD125) is an afucosylated, humanized monoclonal antibody against the alpha chain of the interleukin-5 receptor (IL-5Ra) with potential anti-asthmatic activity. MW: 145.5 kD.
More Information Supplier PageBenserazide HCl (Ro-4-4602) is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.Solutions are unstable and should be fresh-prepared.
More Information Supplier PageBentamapimod (AS602801) is a novel, orally active JNK inhibitor with IC50 values of 80 nM, 90 nM and 230 nM for JNK1, JNK2 and JNK3 respectively.
More Information Supplier PageBentamapimod (AS602801) is a novel, orally active JNK inhibitor with IC50 values of 80 nM, 90 nM and 230 nM for JNK1, JNK2 and JNK3 respectively.
More Information Supplier PageBentiromide is a peptide which is broken down in the pancreas by chymotrypsin. The bentiromide test is a test of pancreatic exocrine function.
More Information Supplier PageBenufutamab (Anti-TNFRSF10B / TRAILR2 / CD262) is an agonistic antibody specificly targeting death receptor 5 (DR5).It has antitumor effects and can be used for the research of multiple myeloma (MM). MW :1145.12 KD.
More Information Supplier PageBenufutamab (Anti-TNFRSF10B / TRAILR2 / CD262) is an agonistic antibody specificly targeting death receptor 5 (DR5).It has antitumor effects and can be used for the research of multiple myeloma (MM). MW :1145.12 KD.
More Information Supplier PageBenufutamab (Anti-TNFRSF10B / TRAILR2 / CD262) is an agonistic antibody specificly targeting death receptor 5 (DR5).It has antitumor effects and can be used for the research of multiple myeloma (MM). MW :1145.12 KD.
More Information Supplier PageBenzalkonium chloride, a detergent and preservative found in health care and household products, is an established irritant.
More Information Supplier PageBenzalkonium chloride, a detergent and preservative found in health care and household products, is an established irritant.
More Information Supplier PageBenzamide, a derivative of benzoic acid, is an inhibitor of poly(ADP-ribose) polymerase with an IC50 of 3.3 μM.
More Information Supplier PageBenzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively.
More Information Supplier PageBenzamidine is an inhibitor of serine proteases with Ki values of 35, 350, and 220 µM for trypsin, plasmin, and thrombin, respectively.
More Information Supplier PageBenzathine penicilline (Benzathine penicillin G) is an antibiotic useful for the treatment of a number of bacterial infections.
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