Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteBalsalazide (Colazal, Giazo), an aminosalicylate and oral prodrug, is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
More Information Supplier PageBalsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Balsalazide Disodium suppress colitis-associated carcinogenesis through modulation of IL-6/STAT3 pathway.
More Information Supplier PageBalsam Pear Extract is extracted from Momordica charantia, which is used in the treatment of diabetes mellitus.
More Information Supplier PageBalsam Pear Powder is extracted from Momordica charantia, which is traditionally known to have health-beneficial effects, mainly on diabetes.
More Information Supplier PageBalstilimab (Anti-PDCD1 / PD-1 / CD279) is a monoclonal antibody targeting the programmed cell death 1 (PD-1, PCD-1; PDCD1). It exhibits potential treatment of cervical cancer. MW :137.3 KD.
More Information Supplier PageBalstilimab (Anti-PDCD1 / PD-1 / CD279) is a monoclonal antibody targeting the programmed cell death 1 (PD-1, PCD-1; PDCD1). It exhibits potential treatment of cervical cancer. MW :137.3 KD.
More Information Supplier PageBalstilimab (Anti-PDCD1 / PD-1 / CD279) is a monoclonal antibody targeting the programmed cell death 1 (PD-1, PCD-1; PDCD1). It exhibits potential treatment of cervical cancer. MW :137.3 KD.
More Information Supplier PageBAM(8-22), a proteolytically cleaved product of proenkephalin A, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1, and induces scratching in mice in an Mrgpr-dependent manner.
More Information Supplier PageBAM 15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced microtubule damage. BAM 15 is also a potent AMPK activator. BAM 15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.
More Information Supplier PageBAM 15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced microtubule damage. BAM 15 is also a potent AMPK activator. BAM 15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.
More Information Supplier PageBAM 15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced microtubule damage. BAM 15 is also a potent AMPK activator. BAM 15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.
More Information Supplier PageBAM 15 is a novel mitochondrial protonophore uncoupler capable of protecting mammals from acute renal ischemic-reperfusion injury and cold-induced microtubule damage. BAM 15 is also a potent AMPK activator. BAM 15 attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.
More Information Supplier PageBAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.
More Information Supplier PageBAM 7 is a direct and selective activator of proapoptotic Bax with EC50 of 3.3 μM.
More Information Supplier PageBAMB-4 (ITPKA-IN-C14) is a new type of membrane permeable ITPKA inhibitor, and IC50 is 37 μM in the Kinase ADP-Glo assay.
More Information Supplier PageBAMB-4 (ITPKA-IN-C14) is a new type of membrane permeable ITPKA inhibitor, and IC50 is 37 μM in the Kinase ADP-Glo assay.
More Information Supplier PageBamboo Sap Extract is extracted from bamboo sap, which is used for the wellness of your skin, hair, and nails.
More Information Supplier PageBamboo Shaving Extract is extracted from the shavings of Bambusa, which has antioxidant activities.
More Information Supplier PageBambuterol HCl(Bambuterol hydrochloride,KWD-2183 hydrochloride) is a potent β-adrenoceptor agonist, used in the treatment of asthma.
More Information Supplier PageBaohuoside I (Icariside II) is a flavonoid isolated from Epimedium koreanum Nakai with anti-inflammatory and anti-cancer activities. It may exert cytotoxic effect via the ROS/MAPK pathway.
More Information Supplier PageBapineuzumab (Anti-Amyloid Beta) is a monoclonal antibody targeting β-amyloid protein (APP). It can be used for the research of Alzheimer’s disease (AD). MW :140.16 KD.
More Information Supplier PageBapineuzumab (Anti-Amyloid Beta) is a monoclonal antibody targeting β-amyloid protein (APP). It can be used for the research of Alzheimer’s disease (AD). MW :140.16 KD.
More Information Supplier PageBapineuzumab (Anti-Amyloid Beta) is a monoclonal antibody targeting β-amyloid protein (APP). It can be used for the research of Alzheimer’s disease (AD). MW :140.16 KD.
More Information Supplier PageBapotulimab (Anti-ILDR2) is a fully human immunoglobulin G2 (IgG2) monoclonal antibody against the immune checkpoint immunoglobulin-like domain containing receptor 2 (ILDR2; Chromosome 1 Open Reading Frame 32; C1orf32), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 145.24 kD.
More Information Supplier PageBapotulimab (Anti-ILDR2) is a fully human immunoglobulin G2 (IgG2) monoclonal antibody against the immune checkpoint immunoglobulin-like domain containing receptor 2 (ILDR2; Chromosome 1 Open Reading Frame 32; C1orf32), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 145.24 kD.
More Information Supplier PageBapotulimab (Anti-ILDR2) is a fully human immunoglobulin G2 (IgG2) monoclonal antibody against the immune checkpoint immunoglobulin-like domain containing receptor 2 (ILDR2; Chromosome 1 Open Reading Frame 32; C1orf32), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 145.24 kD.
More Information Supplier PageBAPTA tetrapotassium salt (BAPTA tetrapotassium) is a non-permeable, selective extracellular calcium chelator, with 105-fold greater affinity for Ca2+ than Mg2+, which is a valuable tool to study the role of calcium in cell signaling.
More Information Supplier PageBAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM.
More Information Supplier PageBAR501 is a potent and selective G protein-coupled bile acid receptor 1 (GPBAR1, GPCR19, TGR5) agonist that effectively transactivates GPBAR1 in HEK293 cells overexpressing a CRE along with GPBAR1 with EC50 of 1 μM.
More Information Supplier PageBAR502 (Compound 30) is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively.
More Information Supplier PageBAR502 (Compound 30) is a dual FXR and GPBAR1 agonist with IC50 values of 2 μM and 0.4 μM, respectively.
More Information Supplier PageDefosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
More Information Supplier PageDefosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
More Information Supplier PageDefosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
More Information Supplier PageDefosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
More Information Supplier PageDefosbarasertib (AZD1152-HQPA, AZD2811, INH-34, Barasertib-HQPA) is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay, ~3700 fold more selective for Aurora B over Aurora A. Phase 1.
More Information Supplier PageBardoxolone (CDDO), acts by releasing Nrf2 from KEAP1,is a highly potent activator of Nrf2 that induce programmed cell death (apoptosis) in cancer cells.
More Information Supplier PageBardoxolone (CDDO), acts by releasing Nrf2 from KEAP1,is a highly potent activator of Nrf2 that induce programmed cell death (apoptosis) in cancer cells.
More Information Supplier PageBardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.
More Information Supplier PageBardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.
More Information Supplier PageBardoxolone Methyl (RTA 402, TP-155, NSC 713200, CDDO Methyl Ester, CDDO-Me) is an IKK inhibitor, showing potent proapoptotic and anti-inflammatory activities; Also a potent Nrf2 activator and nuclear factor-κB (NF-κB) inhibitor. Bardoxolone Methyl abrogates ferroptosis. Bardoxolone methyl induces apoptosis and autophagy in cancer cells.
More Information Supplier PageBarecetamab (Anti-ERBB3/HER3) is a fully human antibody directed against the receptor tyrosine-protein kinase erbB-3 (ErbB3; HER3) with antineoplastic activity. It has the potential to be used in research on recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). MW: 137.96 KD.
More Information Supplier PageBarecetamab (Anti-ERBB3/HER3) is a fully human antibody directed against the receptor tyrosine-protein kinase erbB-3 (ErbB3; HER3) with antineoplastic activity. It has the potential to be used in research on recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). MW: 137.96 KD.
More Information Supplier PageBarecetamab (Anti-ERBB3/HER3) is a fully human antibody directed against the receptor tyrosine-protein kinase erbB-3 (ErbB3; HER3) with antineoplastic activity. It has the potential to be used in research on recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). MW: 137.96 KD.
More Information Supplier PageBaricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research […]
More Information Supplier PageBaricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM in cell-free assays, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2. Baricitinib is found to reduce or interrupt the passage of the virus into target cells and is used in the treatment research […]
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