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Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

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STM2457 25mg  | Purity Not Available

Selleck Chemicals

STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

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STM2457 100mg  | Purity Not Available

Selleck Chemicals

STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

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STM2457 500mg  | Purity Not Available

Selleck Chemicals

STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

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STM2457 10mM/1mL  | Purity Not Available

Selleck Chemicals

STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

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STO-609 5mg  | Purity Not Available

Selleck Chemicals

STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autophosphorylation activities. STO-609 inhibits AMPKK activity and inhibits autophagy.

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STO-609 25mg  | Purity Not Available

Selleck Chemicals

STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autophosphorylation activities. STO-609 inhibits AMPKK activity and inhibits autophagy.

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STO-609 100mg  | Purity Not Available

Selleck Chemicals

STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autophosphorylation activities. STO-609 inhibits AMPKK activity and inhibits autophagy.

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STO-609 1g  | Purity Not Available

Selleck Chemicals

STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kinase(CaM-KK) that inhibits the activities of recombinant CaM-KKα and CaM-KKβ isoforms, with Ki values of 80 and 15 ng/ml, respectively, and also inhibits their autophosphorylation activities. STO-609 inhibits AMPKK activity and inhibits autophagy.

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Streptavidin 1mg  | Purity Not Available

Selleck Chemicals

Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. The dissociation constant (Kd) of the biotin-streptavidin complex is about ~1015 M.Streptavidin has an immunosuppressive role. The Streptavidin protein solution contains 50mM Tris-HCl pH-8 & 0.15M NaCl.

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Streptavidin 5mg  | Purity Not Available

Selleck Chemicals

Streptavidin is a crystalline protein isolated from the bacterium Streptomyces avidinii and possesses biotin-binding ability. The dissociation constant (Kd) of the biotin-streptavidin complex is about ~1015 M.Streptavidin has an immunosuppressive role. The Streptavidin protein solution contains 50mM Tris-HCl pH-8 & 0.15M NaCl.

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Strictosamide 1mg  | Purity Not Available

Selleck Chemicals

Strictosamide is the main representative constituent of Nauclea officinalis Pierre ex Pitard (Rubiaceae) with anti-inflammatory and analgesic activities.

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Strontium Ranelate 50mg  | Purity Not Available

Selleck Chemicals

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

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Strontium Ranelate 200mg  | Purity Not Available

Selleck Chemicals

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

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Strontium Ranelate 10mg  | Purity Not Available

Selleck Chemicals

Strontium Ranelate is a strontium(II) salt of ranelic acid for (-)-desmethoxyverapamil binding to calcium channel with IC50 of 0.5 mM.

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Stylopine 1mg  | Purity Not Available

Selleck Chemicals

Stylopine ((R,S)-Stylopine, Tetrahydrocoptisine) reduces nitric oxide (NO), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta), and the IL-6 production and cyclooxygenase-2 (COX-2) activity caused by the LPS stimulation. Stylopine is a major component of the leaf of Chelidonium majus L.

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Stylopine hydrochloride 1mg  | Purity Not Available

Selleck Chemicals

Stylopine (Tetrahydrocoptisine, Coptisine), a major component of the leaf of Chelidonium majus L., is a protoberberine-type alkaloid that has potential biological activities, including anti-inflammatory activity.

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STZ (Streptozotocin) 200mg  | Purity Not Available

Selleck Chemicals

STZ (Streptozotocin) is a glucosamine-nitrosourea compound derived from Streptomyces achromogenes, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. Streptozotocin induces autophagy and apoptosis. Solutions are unstable and should be fresh-prepared.

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STZ (Streptozotocin) 1g  | Purity Not Available

Selleck Chemicals

STZ (Streptozotocin) is a glucosamine-nitrosourea compound derived from Streptomyces achromogenes, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. Streptozotocin induces autophagy and apoptosis. Solutions are unstable and should be fresh-prepared.

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STZ (Streptozotocin) 50mg  | Purity Not Available

Selleck Chemicals

STZ (Streptozotocin) is a glucosamine-nitrosourea compound derived from Streptomyces achromogenes, which is a DNA-methylating, carcinogenic, antibiotic and diabetes inducing agent. Streptozotocin induces autophagy and apoptosis. Solutions are unstable and should be fresh-prepared.

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SU0268 5mg  | Purity Not Available

Selleck Chemicals

SU0268 is a potent and specific inhibitor of 8-Oxoguanine DNA glycosylase 1 (OGG1), with the IC50 of 0.059 μM.

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SU056 5mg  | Purity Not Available

Selleck Chemicals

SU056 is an inhibitor of Y box binding protein 1 (YB-1) with IC50 of 1.73 μM in Sk0V3 cells.

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SU056 25mg  | Purity Not Available

Selleck Chemicals

SU056 is an inhibitor of Y box binding protein 1 (YB-1) with IC50 of 1.73 μM in Sk0V3 cells.

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SU11274 1g  | Purity Not Available

Selleck Chemicals

SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.

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SU11274 2mg  | Purity Not Available

Selleck Chemicals

SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.

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SU11274 5mg  | Purity Not Available

Selleck Chemicals

SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.

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SU11274 25mg  | Purity Not Available

Selleck Chemicals

SU11274 (PKI-SU11274) is a selective Met (c-Met) inhibitor with IC50 of 10 nM in cell-free assays, no effects on PGDFRβ, EGFR or Tie2. SU11274 induces autophagy, apoptosis and cell cycle arrest.

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SU14813 25mg  | Purity Not Available

Selleck Chemicals

SU14813 (SU 014813) is a multiple receptor tyrosine kinase inhibitor with IC50 of 50 nM, 2 nM, 4 nM and 15 nM for VEGFR2, VEGFR1, PDGFRβ and Kit (c-Kit). SU14813 exhibits potent antiangiogenic and antitumor activity.

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SU14813 5mg  | Purity Not Available

Selleck Chemicals

SU14813 (SU 014813) is a multiple receptor tyrosine kinase inhibitor with IC50 of 50 nM, 2 nM, 4 nM and 15 nM for VEGFR2, VEGFR1, PDGFRβ and Kit (c-Kit). SU14813 exhibits potent antiangiogenic and antitumor activity.

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SU1498 5mg  | Purity Not Available

Selleck Chemicals

SU1498, a powerful inhibitor of KDR (IC50 = 0.7 μM), stimulates accumulation of phosphorylated ERK1/2 in endothelial cells.

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SU3327 5mg  | Purity Not Available

Selleck Chemicals

SU3327 is a potent, selective and substrate-competitive c-Jun N-terminal kinase (JNK) inhibitor with an IC50 of 0.7 μM.

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SU5204 5mg  | Purity Not Available

Selleck Chemicals

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.

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SU5205 5mg  | Purity Not Available

Selleck Chemicals

SU5205 is an inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 9.6 µM.

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SU5208 5mg  | Purity Not Available

Selleck Chemicals

SU5208(3-[(Thien-2-yl)methylene]-2-indolinone) is an inhibitor of vascular endothelial growth factor receptor-2 (VEGFR2).

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SU5214 5mg  | Purity Not Available

Selleck Chemicals

SU5214 is a inhibitor of VEGF receptor 2 (VEGFR2/FLK-1) with IC50 of 14.8 µM and EGFR with IC50 of 36.7 µm, respectively.

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SU5402 200mg  | Purity Not Available

Selleck Chemicals

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

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SU5402 1g  | Purity Not Available

Selleck Chemicals

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

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SU5402 10mM/1mL  | Purity Not Available

Selleck Chemicals

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

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SU5402 10mg  | Purity Not Available

Selleck Chemicals

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

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SU5402 50mg  | Purity Not Available

Selleck Chemicals

SU5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.

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SU5408 25mg  | Purity Not Available

Selleck Chemicals

SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and selective inhibitor of VEGFR2 Kinase with IC50 of 70 nM.

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SU5408 5mg  | Purity Not Available

Selleck Chemicals

SU5408 (VEGFR2 Kinase Inhibitor I) is a potent and selective inhibitor of VEGFR2 Kinase with IC50 of 70 nM.

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SU5614 25mg  | Purity Not Available

Selleck Chemicals

SU5614 (Chloro-SU5416, Chloro-Semaxanib) is a small molecule receptor tyrosine kinases (RTK) inhibitor of VEGFR-2, c-kit, and both wild-type and mutant FLT3. SU5614 reduces cell proliferation and induces apoptosis.

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SU5614 5mg  | Purity Not Available

Selleck Chemicals

SU5614 (Chloro-SU5416, Chloro-Semaxanib) is a small molecule receptor tyrosine kinases (RTK) inhibitor of VEGFR-2, c-kit, and both wild-type and mutant FLT3. SU5614 reduces cell proliferation and induces apoptosis.

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SU6656 10mM/1mL  | Purity Not Available

Selleck Chemicals

SU 6656 is a selective Src family kinase inhibitor with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.

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SU6656 5mg  | Purity Not Available

Selleck Chemicals

SU 6656 is a selective Src family kinase inhibitor with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.

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SU6656 25mg  | Purity Not Available

Selleck Chemicals

SU 6656 is a selective Src family kinase inhibitor with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.

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SU6656 100mg  | Purity Not Available

Selleck Chemicals

SU 6656 is a selective Src family kinase inhibitor with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.

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