Selleck Chemicals

Selleck Chemicals logo

Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

Company Website

Product Listing

SR-12813 10mg  | Purity Not Available

Selleck Chemicals

SR-12813 is a pregnane X receptor (PXR) agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM.

More Information Supplier Page

SR-12813 50mg  | Purity Not Available

Selleck Chemicals

SR-12813 is a pregnane X receptor (PXR) agonist and HMG-CoA reductase inhibitor with an IC50 of 850 nM.

More Information Supplier Page

SR-18292 1g  | Purity Not Available

Selleck Chemicals

SR-18292 inhibits PGC-1α gluconeogenic activity and reduces co-activation of HNF4α by modulating the interaction between GCN5 and PGC-1α.

More Information Supplier Page

SR-18292 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR-18292 inhibits PGC-1α gluconeogenic activity and reduces co-activation of HNF4α by modulating the interaction between GCN5 and PGC-1α.

More Information Supplier Page

SR-18292 10mg  | Purity Not Available

Selleck Chemicals

SR-18292 inhibits PGC-1α gluconeogenic activity and reduces co-activation of HNF4α by modulating the interaction between GCN5 and PGC-1α.

More Information Supplier Page

SR-18292 100mg  | Purity Not Available

Selleck Chemicals

SR-18292 inhibits PGC-1α gluconeogenic activity and reduces co-activation of HNF4α by modulating the interaction between GCN5 and PGC-1α.

More Information Supplier Page

SR-3029 2mg  | Purity Not Available

Selleck Chemicals

SR-3029 is a potent and selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 values of 44 and 260 nM for CK1δ and CK1ε, respectively.

More Information Supplier Page

SR-3029 5mg  | Purity Not Available

Selleck Chemicals

SR-3029 is a potent and selective casein kinase 1δ/1ε (CK1δ/ε) inhibitor with IC50 values of 44 and 260 nM for CK1δ and CK1ε, respectively.

More Information Supplier Page

SR-4370 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR-4370 is a potent and selective inhibitor of class I HDACs with IC50 of 0.13 µM, 0.58 µM, 0.006 µM, 2.3 µM, 3.7 µM for HDAC 1, HDAC 2, HDAC 3, HDAC 8, HDAC 6, respectively.SR-4370 suppresses AR signaling and in vivo prostate tumor growth.

More Information Supplier Page

SR-4370 5mg  | Purity Not Available

Selleck Chemicals

SR-4370 is a potent and selective inhibitor of class I HDACs with IC50 of 0.13 µM, 0.58 µM, 0.006 µM, 2.3 µM, 3.7 µM for HDAC 1, HDAC 2, HDAC 3, HDAC 8, HDAC 6, respectively.SR-4370 suppresses AR signaling and in vivo prostate tumor growth.

More Information Supplier Page

SR-4370 25mg  | Purity Not Available

Selleck Chemicals

SR-4370 is a potent and selective inhibitor of class I HDACs with IC50 of 0.13 µM, 0.58 µM, 0.006 µM, 2.3 µM, 3.7 µM for HDAC 1, HDAC 2, HDAC 3, HDAC 8, HDAC 6, respectively.SR-4370 suppresses AR signaling and in vivo prostate tumor growth.

More Information Supplier Page

SR-4835 25mg  | Purity Not Available

Selleck Chemicals

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

More Information Supplier Page

SR-4835 5mg  | Purity Not Available

Selleck Chemicals

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

More Information Supplier Page

SR-4835 100mg  | Purity Not Available

Selleck Chemicals

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

More Information Supplier Page

SR-4835 1g  | Purity Not Available

Selleck Chemicals

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

More Information Supplier Page

SR-4835 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR-4835 is a highly selective dual inhibitor of CDK12 and CDK13 with IC50 of 99 nM and Kd of 98 nM for CDK12 and IC50 of 4.9 nM for CDK13. SR-4835 disables triple-negative breast cancer (TNBC) cells. SR-4835 promotes synergy with DNA-damaging chemotherapy and PARP inhibitors.

More Information Supplier Page

SR-717 lithium 25mg  | Purity Not Available

Selleck Chemicals

SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 […]

More Information Supplier Page

SR-717 lithium 5mg  | Purity Not Available

Selleck Chemicals

SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 […]

More Information Supplier Page

SR-717 lithium 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR-717 lithium is a non-nucleotide STING agonist that demonstrates broad interspecies and interallelic specificity with EC50 of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 (cGAS KO) cell lines, respectively. SR-717 lithium also induces the expression of clinically relevant targets, including programmed cell death 1 ligand 1 (PD-L1), in a STING-dependent manner. SR-717 […]

More Information Supplier Page

SR1001 5mg  | Purity Not Available

Selleck Chemicals

SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively.

More Information Supplier Page

SR1001 25mg  | Purity Not Available

Selleck Chemicals

SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively.

More Information Supplier Page

SR1078 5mg  | Purity Not Available

Selleck Chemicals

SR1078, a synthetic ligand for RORα and RORγ, functions as a RORα/γ agonist.

More Information Supplier Page

SR1078 25mg  | Purity Not Available

Selleck Chemicals

SR1078, a synthetic ligand for RORα and RORγ, functions as a RORα/γ agonist.

More Information Supplier Page

SR1078 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR1078, a synthetic ligand for RORα and RORγ, functions as a RORα/γ agonist.

More Information Supplier Page

SR18662 25mg  | Purity Not Available

Selleck Chemicals

SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.

More Information Supplier Page

SR18662 5mg  | Purity Not Available

Selleck Chemicals

SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.

More Information Supplier Page

SR18662 10mM/1mL  | Purity Not Available

Selleck Chemicals

SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.

More Information Supplier Page

SR3335 25mg  | Purity Not Available

Selleck Chemicals

SR3335 (ML-176) is a selective and inverse agonist of retinoic acid receptor-related receptor α (RORα) that directly binds to RORα with Ki of 220 nM.

More Information Supplier Page

SR3335 5mg  | Purity Not Available

Selleck Chemicals

SR3335 (ML-176) is a selective and inverse agonist of retinoic acid receptor-related receptor α (RORα) that directly binds to RORα with Ki of 220 nM.

More Information Supplier Page

SR59230A 25mg  | Purity Not Available

Selleck Chemicals

SR59230A is a blood-brain barrier penetrating, potent and selective antagonist of β3-adrenergic receptor with IC50 of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively.

More Information Supplier Page

SR59230A 5mg  | Purity Not Available

Selleck Chemicals

SR59230A is a blood-brain barrier penetrating, potent and selective antagonist of β3-adrenergic receptor with IC50 of 40 nM, 408 nM, and 648 nM for β3, β1, and β2 receptors, respectively.

More Information Supplier Page

SR8278 25mg  | Purity Not Available

Selleck Chemicals

SR8278 is a competitive antagonist of nuclear heme receptor REV-ERB with an EC50 of 0.47 μM for REV-ERBα.

More Information Supplier Page

SR8278 5mg  | Purity Not Available

Selleck Chemicals

SR8278 is a competitive antagonist of nuclear heme receptor REV-ERB with an EC50 of 0.47 μM for REV-ERBα.

More Information Supplier Page

SR9011 5mg  | Purity Not Available

Selleck Chemicals

SR9011 is a REV-ERBα/β agonist with IC50s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. It is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi.

More Information Supplier Page

SR9011 25mg  | Purity Not Available

Selleck Chemicals

SR9011 is a REV-ERBα/β agonist with IC50s of 790 nM and 560 nM for REV-ERBα and REV-ERBβ, respectively. It is specifically lethal to cancer cells and oncogene-induced senescent cells, including melanocytic naevi.

More Information Supplier Page

SR95531 5mg  | Purity Not Available

Selleck Chemicals

Gabazine(SR95531) is a potent competitive and allosteric antagonist of the GABAA receptor, with an IC50 for the GABA receptor of 9 µM.

More Information Supplier Page

SR95531 25mg  | Purity Not Available

Selleck Chemicals

Gabazine(SR95531) is a potent competitive and allosteric antagonist of the GABAA receptor, with an IC50 for the GABA receptor of 9 µM.

More Information Supplier Page

Src Inhibitor 1 5mg  | Purity Not Available

Selleck Chemicals

Src Inhibitor 1 is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.

More Information Supplier Page

Src Inhibitor 1 25mg  | Purity Not Available

Selleck Chemicals

Src Inhibitor 1 is a potent competitive inhibitor of both Src and Lck (IC50 = 44 and 88 nM, respectively), as well as Csk and Yes.

More Information Supplier Page

SRI-011381 (C381) 100mg  | Purity Not Available

Selleck Chemicals

SRI-011381 (C381) is a novel agonist of the TGF-beta signaling pathway for treatment of Alzheimer’s disease.

More Information Supplier Page

SRI-011381 (C381) 10mM/1mL  | Purity Not Available

Selleck Chemicals

SRI-011381 (C381) is a novel agonist of the TGF-beta signaling pathway for treatment of Alzheimer’s disease.

More Information Supplier Page

SRI-011381 (C381) 5mg  | Purity Not Available

Selleck Chemicals

SRI-011381 (C381) is a novel agonist of the TGF-beta signaling pathway for treatment of Alzheimer’s disease.

More Information Supplier Page

SRI-011381 (C381) 25mg  | Purity Not Available

Selleck Chemicals

SRI-011381 (C381) is a novel agonist of the TGF-beta signaling pathway for treatment of Alzheimer’s disease.

More Information Supplier Page