Selleck Chemicals

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Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

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SJB2-043 5mg  | Purity Not Available

Selleck Chemicals

SJB2-043 is a potent USP1 inhibitor that inhibits the activity of native USP1/UAF1 with IC50 of 544 nM.

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SKA-31 5mg  | Purity Not Available

Selleck Chemicals

SKA-31(Naphtho[1,2-d]thiazol-2-ylamine) is a potent potassium channel activator with EC50s of 260 nM, 1.9 μM, 2.9 μM, and 2.9 μM for KCa3.1, KCa2.2, KCa2.1 and KCa2.3, respectively.

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Skatole 25mg  | Purity Not Available

Selleck Chemicals

Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

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Skatole 1g  | Purity Not Available

Selleck Chemicals

Skatole (3-methylindole, Scatole) is a mildly toxic white crystalline organic compound that occurs naturally in feces. It has a fairly broad bacteriostatic effect.

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SKF-86002 5mg  | Purity Not Available

Selleck Chemicals

SKF-86002 is an orally active p38 MAPK inhibitor, inhibits lipopolysaccharide (LPS)-stimulate human monocyte IL-1 and TNF-α production with IC50 of 1 μM, also inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.

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SKF96365 10mg  | Purity Not Available

Selleck Chemicals

SKF96365, originally identified as a blocker of receptor-mediated calcium entry, is widely used diagnostically, as a blocker of transient receptor potential canonical type (TRPC) channels.

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SKF96365 50mg  | Purity Not Available

Selleck Chemicals

SKF96365, originally identified as a blocker of receptor-mediated calcium entry, is widely used diagnostically, as a blocker of transient receptor potential canonical type (TRPC) channels.

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SKI II 25mg  | Purity Not Available

Selleck Chemicals

SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.

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SKI II 100mg  | Purity Not Available

Selleck Chemicals

SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.

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SKI II 1g  | Purity Not Available

Selleck Chemicals

SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.

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SKI II 10mM/1mL  | Purity Not Available

Selleck Chemicals

SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.

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SKI-178 5mg  | Purity Not Available

Selleck Chemicals

SKI-178 is a potent inhibitors of sphingosine kinase-1 (SphK1) and SphK2 with IC50 values ranging from ∼500 nM to ∼1 μM depending on AML cell lines.

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SKI-V 5mg  | Purity Not Available

Selleck Chemicals

SKI V is a noncompetitive and potent inhibitor of non-lipid sphingosine kinase with IC50 of 2 μM for GST-hSK. SKI-V also inhibits PI3K with IC50 of 6 μM for hPI3k. SKI-V decreases formation of the mitogenic second messenger sphingosine-1-phosphate (S1P) and induces apoptosis with antitumor activity.

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Skimmianine 1mg  | Purity Not Available

Selleck Chemicals

Skimmianine, a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect, exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity.

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Skimmianine 5mg  | Purity Not Available

Selleck Chemicals

Skimmianine, a furoquinoline alkaloid present mainly in the Rutaceae family, with antispastic, anti-inflammatory activities and antiplatelet aggregation effect, exhibits cytotoxicity against a variety of cancer cell lines and genotoxicity.

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Skimmin 5mg  | Purity Not Available

Selleck Chemicals

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent.

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Skimmin 1mg  | Purity Not Available

Selleck Chemicals

Skimmin is one of the major pharmacologically active molecules present in Hydrangea paniculata, a medical herb used in the traditional Chinese medicine as an anti-inflammatory agent.

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SKL2001 1g  | Purity Not Available

Selleck Chemicals

SKL2001 is a novel agonist of the Wnt/β-catenin pathway. It disrupts the Axin/β-catenin interaction.

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SKL2001 10mM/1mL  | Purity Not Available

Selleck Chemicals

SKL2001 is a novel agonist of the Wnt/β-catenin pathway. It disrupts the Axin/β-catenin interaction.

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SKL2001 10mg  | Purity Not Available

Selleck Chemicals

SKL2001 is a novel agonist of the Wnt/β-catenin pathway. It disrupts the Axin/β-catenin interaction.

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SKL2001 50mg  | Purity Not Available

Selleck Chemicals

SKL2001 is a novel agonist of the Wnt/β-catenin pathway. It disrupts the Axin/β-catenin interaction.

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SKLB 610 5mg  | Purity Not Available

Selleck Chemicals

SKLB-610 is a multi-target inhibitor of the tyrosine kinases. It is most potent against VEGFR2 and exhibits slightly weaker inhibitor of FGFR2 and PDGFR.

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SKLB-197 5mg  | Purity Not Available

Selleck Chemicals

SKLB-197 exerts selectively inhibition against ataxia telangiectasia mutated and Rad3-related (ATR) kinase with IC50 of 0.013 μM, also displays potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.

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SKLB-197 100mg  | Purity Not Available

Selleck Chemicals

SKLB-197 exerts selectively inhibition against ataxia telangiectasia mutated and Rad3-related (ATR) kinase with IC50 of 0.013 μM, also displays potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.

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SKLB-23bb 25mg  | Purity Not Available

Selleck Chemicals

SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor with IC50 values under 100 nmol/L, against most of the cell lines checked. It also has microtubule-disrupting ability.

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SKLB-23bb 100mg  | Purity Not Available

Selleck Chemicals

SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor with IC50 values under 100 nmol/L, against most of the cell lines checked. It also has microtubule-disrupting ability.

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SKLB-23bb 1g  | Purity Not Available

Selleck Chemicals

SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor with IC50 values under 100 nmol/L, against most of the cell lines checked. It also has microtubule-disrupting ability.

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SKLB-23bb 2mg  | Purity Not Available

Selleck Chemicals

SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor with IC50 values under 100 nmol/L, against most of the cell lines checked. It also has microtubule-disrupting ability.

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Skp2 inhibitor C1 (SKPin C1) 5mg  | Purity Not Available

Selleck Chemicals

Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.

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Skp2 inhibitor C1 (SKPin C1) 25mg  | Purity Not Available

Selleck Chemicals

Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.

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Skp2 inhibitor C1 (SKPin C1) 100mg  | Purity Not Available

Selleck Chemicals

Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.

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Skp2 inhibitor C1 (SKPin C1) 1g  | Purity Not Available

Selleck Chemicals

Skp2 inhibitor C1 (SKPin C1) is a specific and selective small-molecule inhibitor of Skp2-mediated p27 degradation by reducing p27 binding through key compound-receptor contacts.

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SL-327 25mg  | Purity Not Available

Selleck Chemicals

SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII;capable of transport through the blood-brain barrier.

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SLC13A5-IN-1 25mg  | Purity Not Available

Selleck Chemicals

SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.

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SLC13A5-IN-1 5mg  | Purity Not Available

Selleck Chemicals

SLC13A5-IN-1 is a selective inhibitor of sodium-citrate co-transporter (SLC13A5/NaCT). It completely blocks the uptake of 14 C-citrate and has the potential for the treatment of metabolic and/or cardiovascular diseases.

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SM 324405 25mg  | Purity Not Available

Selleck Chemicals

SM 324405 (compound 9e) is a potent and selective Toll-like receptor 7 (TLR7) agonist with EC50 of 50 nM.

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SM 324405 5mg  | Purity Not Available

Selleck Chemicals

SM 324405 (compound 9e) is a potent and selective Toll-like receptor 7 (TLR7) agonist with EC50 of 50 nM.

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SM-102 5mg  | Purity Not Available

Selleck Chemicals

SM-102 is a amino cationic lipid used to form the nanoparticle which carries the mRNA to cells in the body.

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SM-102 25mg  | Purity Not Available

Selleck Chemicals

SM-102 is a amino cationic lipid used to form the nanoparticle which carries the mRNA to cells in the body.

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SM-102 100mg  | Purity Not Available

Selleck Chemicals

SM-102 is a amino cationic lipid used to form the nanoparticle which carries the mRNA to cells in the body.

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SM-102 1g  | Purity Not Available

Selleck Chemicals

SM-102 is a amino cationic lipid used to form the nanoparticle which carries the mRNA to cells in the body.

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