Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteSerdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.
More Information Supplier PageSerdemetan (JNJ-26854165) acts as a HDM2 ubiquitin ligase antagonist and also induces early apoptosis in p53 wild-type cells, inhibits cellular proliferation followed by delayed apoptosis in the absence of functional p53. Phase 1.
More Information Supplier PageSeribantumab (Anti-ERBB3 / HER3) is a fully human IgG2 monoclonal antibody that targets HER3. It inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. MW : 143.14 KD.
More Information Supplier PageSeribantumab (Anti-ERBB3 / HER3) is a fully human IgG2 monoclonal antibody that targets HER3. It inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. MW : 143.14 KD.
More Information Supplier PageSeribantumab (Anti-ERBB3 / HER3) is a fully human IgG2 monoclonal antibody that targets HER3. It inhibits neuregulin 1 (NRG1) fusion-dependent tumorigenesis in vitro and in vivo in breast, lung and ovarian patient-derived cancer models. MW : 143.14 KD.
More Information Supplier PageSerotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
More Information Supplier PageSerotonin (5-HT) HCl is a monoamine neurotransmitter and Endogenous 5-HT receptor agonist.
More Information Supplier PageSerotonin (5-Hydroxytryptamine) creatinine sulfate monohydrate is an active endogenous metabolite.
More Information Supplier PageSerplulimab (Anti-PDCD1 / PD-1 / CD279) is a humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell death protein 1 (PD-1; PDCD1; CD279), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.5 kD.
More Information Supplier PageSerplulimab (Anti-PDCD1 / PD-1 / CD279) is a humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell death protein 1 (PD-1; PDCD1; CD279), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.5 kD.
More Information Supplier PageSerplulimab (Anti-PDCD1 / PD-1 / CD279) is a humanized monoclonal antibody directed against the negative immunoregulatory human cell receptor programmed cell death protein 1 (PD-1; PDCD1; CD279), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 145.5 kD.
More Information Supplier PageSertaconazole nitrate (FI-7045,FI7056) is a topical broad-spectrum antifungal that is developed to provide an additional agent for the treatment of superficial cutaneous and mucosal infections.
More Information Supplier PageSesame oil is a supplement that has anti-inflammatory and antioxidant properties, which make it effective for reducing atherosclerosis and the risk of cardiovascular disease.
More Information Supplier PageSesame oil is a supplement that has anti-inflammatory and antioxidant properties, which make it effective for reducing atherosclerosis and the risk of cardiovascular disease.
More Information Supplier PageSesamin (Fagarol, Fsesamin), a lignan isolated from the bark of Fagara plants and from sesame oil, exhibits various health benefits.
More Information Supplier PageSesamol (1,3-Benzodioxol-5-ol, 3,4-Methylenedioxyphenol), a natural organic compound, is regarded as a major antioxidant component in the oil with chemoprevention, antimutagenic, and antihepatotoxic activities. It induces apoptosis of cancer and cardiovascular cells.
More Information Supplier PageSesamoside, a main chemical ingredient iridoid glycoside from Lamiophlomic rotata, has analgesic and anti-inflammatory effects in animal studies.
More Information Supplier PageSetanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetariae Fructus Germinatus Extract is extracted from Setariae Fructus Germinatus, which is known to have a significant impact on liver diseases.
More Information Supplier PageSetipiprant (ACT-129968, KYTH-105) is a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2) that that has been shown to have greater specificity for DP2 (CRTH2) than for DP1.
More Information Supplier PageSetmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.
More Information Supplier PageSetmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.
More Information Supplier PageSetmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.
More Information Supplier PageSetmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.
More Information Supplier PageSetmelanotide (RM-493, BIM-22493, CAM 4072) is a cyclic peptide full agonist of melanocortin-4 receptor (MC4R) with an EC50 of 0.27 nM and a Ki of 2.1 nM.
More Information Supplier PageSetoxaximab (Anti-Shiga toxin (E.coli)) is a mouse chimeric IgG1(kappa) antiboy that target shiga toxin 1 and shiga toxin 2, produced by E. coli. It can be used in the treatment of hemolytic-uremic syndrome (HUS). MW :147.08 KD.
More Information Supplier PageSetoxaximab (Anti-Shiga toxin (E.coli)) is a mouse chimeric IgG1(kappa) antiboy that target shiga toxin 1 and shiga toxin 2, produced by E. coli. It can be used in the treatment of hemolytic-uremic syndrome (HUS). MW :147.08 KD.
More Information Supplier PageSetoxaximab (Anti-Shiga toxin (E.coli)) is a mouse chimeric IgG1(kappa) antiboy that target shiga toxin 1 and shiga toxin 2, produced by E. coli. It can be used in the treatment of hemolytic-uremic syndrome (HUS). MW :147.08 KD.
More Information Supplier PageSetrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.
More Information Supplier PageSetrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.
More Information Supplier PageSetrusumab (Anti-SOST / Sclerostin) is a fully humanized monoclonal antibody directed against sclerostin. Setrusumab effectively improves bone strength and has the potential to be used in the research of Osteogenesis Imperfecta (OI). MW :143.44 kD.
More Information Supplier PageSevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion.
More Information Supplier PageSevelamer HCl is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption.
More Information Supplier PageSF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
More Information Supplier PageSF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
More Information Supplier PageSF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
More Information Supplier PageSF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
More Information Supplier PageSF1670 is a highly potent and specific PTEN inhibitor with IC50 of 2 μM.
More Information Supplier PageSF2523 is a highly selective and potent inhibitor of PI3K with IC50 values of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.
More Information Supplier PageSF2523 is a highly selective and potent inhibitor of PI3K with IC50 values of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively.
More Information Supplier PageSGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.
More Information Supplier PageSGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.
More Information Supplier PageSGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.
More Information Supplier PageSGC-CBP30 is a potent CREBBP/EP300 inhibitor with IC50 of 21 nM and 38 nM in cell-free assays, respectively. Exhibits 40-fold and 250-fold selectivity for CBP over the first BRD of BRD4 (BRD4(1)) and BRD4(2) respectively.
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