Selleck Chemicals
Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
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Selleck Chemicals
Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
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Selleck Chemicals
Semaxanib (SU5416, semaxinib) is a potent and selective VEGFR(Flk-1/KDR) inhibitor with IC50 of 1.23 μM, 20-fold more selective for VEGFR than PDGFRβ, lack of activity against EGFR, InsR and FGFR. Phase 3.
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Semen Aesculi Extract is extracted from Aesculus chinensis Bunge, which can suppress the metastasis of triple-negative breast cancer by inhibiting epithelial-mesenchymal transition via down-regulating LOXL2 expression.
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Semen astragali complanati Extract is extracted from Semen Astragali Complanati, the dried ripe seed of Flatstem Milkvetch (Astragalus complanatus Bunge) (Leguminosae). The major contents of Semen astragali complanati include fatty acids, amino acids, polysaccharides, flavonoids, triterpene glycosides and trace elements. Semen astragali complanati exhibits a number of therapeutic effects on chronic diseases such as cardiovascular […]
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Semen Canavaliae Extract is extracted from Canavalia Gladiate,, which is a natural antioxidant and antibacterial agent with potential health benefits as well as application in the food industry.
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Semen Lablab Album Extract is extracted from Baibiandouren (Lablab Semen Album), a white seed from the leguminosae plant Dolichos lablab L. Tuchao Baibiandouren (Lablab Semen Album fried with earth, TCBBDR) exerts therapeutic effects on diabetes through multi-compound and multi-target collaboration.
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Semen litchi Extract is extracted from Litchi chinensis, which has an anti-hepatoma effect and inhibits angiogenesis by targeting VEGFR in hepatocellular carcinoma.
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Selleck Chemicals
Semen Pruni Extract is extracted from Semen pruni, which is used for oedema, dermatophytosis, hypertension, constipation, chronic tracheitis, and other conditions.
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Semen Ziziphi Spinosae Extract is extracted from the seeds of Semen Ziziphi Spinosae, which can attenuate blood-brain barrier dysfunction induced by lipopolysaccharide by targeting the FAK-DOCK180-Rac1-WAVE2-Arp3 signaling pathway.
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Selleck Chemicals
Selleck Chemicals
Seminis Juglandis Septum Extract is obtained from Diaphragma juglandis, which is the dry wood diaphragm of walnut kernel, is one of the well-known by-products of walnut production.
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Semorinemab (Anti-Tau) is a humanized IgG4 monoclonal antibody that targets the N-terminal domain of tau (amino acid residues 6-23). Semorinemab has the potential to be used in research on Alzheimer’s disease. MW : 150 kD.
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Selleck Chemicals
Semorinemab (Anti-Tau) is a humanized IgG4 monoclonal antibody that targets the N-terminal domain of tau (amino acid residues 6-23). Semorinemab has the potential to be used in research on Alzheimer’s disease. MW : 150 kD.
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Semorinemab (Anti-Tau) is a humanized IgG4 monoclonal antibody that targets the N-terminal domain of tau (amino acid residues 6-23). Semorinemab has the potential to be used in research on Alzheimer’s disease. MW : 150 kD.
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Senecioic acid (3-Methylcrotonic acid, 3,3-Dimethylacrylic acid, β-Methylcrotonic Acid) is an unsaturated fatty acid found in the pheromones of mealybug species and appears in the urine of patients with 3-Methylcrotonic aciduria.
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Senegenin
1mg
| Purity Not Available
Selleck Chemicals
Senegenin (Tenuigenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and antiinflammatory activity.
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Senexin A
5mg
| Purity Not Available
Selleck Chemicals
Senexin A is a potent and selective inhibitor of CDK8 and its nearest relative, CDK19 with Kd values of 0.83 μM and 0.31 μM for CDK8 and CDK19 ATP site binding, respectively.
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Senexin A
25mg
| Purity Not Available
Selleck Chemicals
Senexin A is a potent and selective inhibitor of CDK8 and its nearest relative, CDK19 with Kd values of 0.83 μM and 0.31 μM for CDK8 and CDK19 ATP site binding, respectively.
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Senicapoc (ICA-17043) is a Gardos channel(Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.
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Senicapoc (ICA-17043) is a Gardos channel(Ca2+-activated K+ channel; KCa3.1) blocker with an IC50 of 11 nM and produces dose-dependent increases in hemoglobin and decreases in markers of hemolysis. Senicapoc blocks Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 nM and inhibits RBC dehydration with IC50 of 30 nM.
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Senkyunolide A is one of the major bioactive ingredients in Rhizoma Chuanxiong, a Chinese medicinal herb commonly used for the treatment of cardiovascular ailments.,
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Senkyunolide I (SEI, SENI) is an orally active compound isolated from Ligusticum chuanxiong with analgesic, anti-migraine, neuroprotective, anti-oxidation and anti-apoptosis activities. Senkyunolide I (SEI, SENI) up-regulates the phosphorylation of Erk1/2 and induces Nrf2 nuclear translocation with enhanced HO-1 and NQO1 expressions. Senkyunolide I (SEI, SENI) promotes the ratio of Bcl-2/Bax and inhibits the expressions of […]
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Senkyunolide I (SEI, SENI) is an orally active compound isolated from Ligusticum chuanxiong with analgesic, anti-migraine, neuroprotective, anti-oxidation and anti-apoptosis activities. Senkyunolide I (SEI, SENI) up-regulates the phosphorylation of Erk1/2 and induces Nrf2 nuclear translocation with enhanced HO-1 and NQO1 expressions. Senkyunolide I (SEI, SENI) promotes the ratio of Bcl-2/Bax and inhibits the expressions of […]
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Sennoside A
5mg
| Purity Not Available
Selleck Chemicals
Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
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Sennoside A
25mg
| Purity Not Available
Selleck Chemicals
Sennoside A (NSC 112929), a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.
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Sennoside B
5mg
| Purity Not Available
Selleck Chemicals
Sennoside B
25mg
| Purity Not Available
Selleck Chemicals
Selleck Chemicals
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast […]
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Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast […]
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Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast […]
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Selleck Chemicals
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast […]
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Selleck Chemicals
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM in HeLa-SURP-luc and CHO-SV40-luc cells; does not significantly inhibit SV40 promoter activity, but is observed to slightly inhibit the interaction of Survivin with XIAP. YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast […]
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Sephin-1
5mg
| Purity Not Available
Selleck Chemicals
Sephin-1 (NSC-65390) is a selective inhibitor of a holophosphatase, a small molecule that safely and selectively inhibits a regulatory subunit of protein phosphatase 1 in vivo. Sephin-1 (NSC-65390) selectively bounds and inhibits the stress-induced PPP1R15A.
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Sequoyitol
1mg
| Purity Not Available
Selleck Chemicals
Sequoia alcohol (Sequoyitol) is isolated from Taxus natural organic compounds, it can be used to treat diabetes and other indications.
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Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
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Selleck Chemicals
Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
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Selleck Chemicals
Serabelisib (TAK-117, INK-1117, MLN-1117) is a potent and selective oral PI3Kα isoform inhibitor (IC50 of 21 nmol/L against PI3Kα) that has demonstrated > 100-fold selectivity relative to other class I PI3K family members (PI3Kβ/γ/δ) and mTOR, and a high degree of selectivity against many other kinase.
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Selleck Chemicals
Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.
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Selleck Chemicals
Seralutinib (PK10571, GB002) is a novel PDGFR kinase inhibitor with IC50s of 8 nM and 10 nM for PDGFRα and PDGFRβ in enzyme assays, respectively.
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Seratrodast (AA-2414, ABT-001) is a potent and selective thromboxane A2 receptor (TP) antagonist which is used primarily in the treatment of asthma and used as anti-inflammatory agent.
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Serclutamab (Anti-ERBB1 / EGFR / HER1) is a monoclonal antibody targeting epidermal growth factor receptor (EGFR). It can be used in research of advanced solid tumors for advanced glioblastoma. MW :150 KD.
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Serclutamab (Anti-ERBB1 / EGFR / HER1) is a monoclonal antibody targeting epidermal growth factor receptor (EGFR). It can be used in research of advanced solid tumors for advanced glioblastoma. MW :150 KD.
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Selleck Chemicals
Serclutamab (Anti-ERBB1 / EGFR / HER1) is a monoclonal antibody targeting epidermal growth factor receptor (EGFR). It can be used in research of advanced solid tumors for advanced glioblastoma. MW :150 KD.
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Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.
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Serclutamab Talirine (ABBV-321), is an antibody-drug conjugate (ADC) composed of an humanized immunoglobulin G1 anti-EGFR monoclonal antibody conjugated to a pyrrolobenzodiazepine (PBD) dimer via a maleimidocaproyl-valine-alanine linker. Serclutamab Talirine has the potential for use in advanced solid tumors associated with overexpression of the epidermal growth factor receptor (EGFR) or its ligands.
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