Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteQStatin is a potent and selective inhibitor of SmcR (V. harveyi LuxR homologue) with an EC50 of 208.9 nM, binding tightly to SmcR and changes the flexibility of the protein, thereby altering its transcription regulatory activity, which can be a sustainable antivibriosis agent useful in aquacultures.
More Information Supplier PageQuassia Extract is extracted from Quassia, which can be used in the treatment of diabetes and associated dyslipidemia.
More Information Supplier PageQuavonlimab (Anti-CTLA-4 / CD152) is a monoclonal antibody targeting the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). It exhibits efficacy in first-line treatment of advanced non-small-cell lung cancer. MW :144.24 KD.
More Information Supplier PageQuavonlimab (Anti-CTLA-4 / CD152) is a monoclonal antibody targeting the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). It exhibits efficacy in first-line treatment of advanced non-small-cell lung cancer. MW :144.24 KD.
More Information Supplier PageQuavonlimab (Anti-CTLA-4 / CD152) is a monoclonal antibody targeting the cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4). It exhibits efficacy in first-line treatment of advanced non-small-cell lung cancer. MW :144.24 KD.
More Information Supplier PageQuercetagetin (6-Hydroxyquercetin), a flavonoid, is a moderately potent and selective, cell-permeable Pim-1 kinase inhibitor with IC50 of 0.34 μM.
More Information Supplier PageQuercetin, a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.
More Information Supplier PageQuercetin, a natural flavonoid present in vegetables, fruit and wine, is a stimulator of recombinant SIRT1 and also a PI3K inhibitor with IC50 of 2.4-5.4 μM. Quercetin induces mitophagy, apoptosis and protective autophagy. Phase 4.
More Information Supplier PageQuercetin 3-O-β-D-glucose-7-O-β-D-gentiobioside (Quercetin 3-O-β-D-glucose-7-O-β-D-gentiobiosiden, Quercetin-3-O-beta-D-glucose-7-O-beta-D-gentiobioside) is an active constituent of Descurainiae Semen.
More Information Supplier PageQuercetin 3-O-β-D-glucuronide (Miquelianin, Q3GA) is one of the quercetin metabolites with antioxidant activity.
More Information Supplier PageQuercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a natural flavonoid, is a stimulator of recombinant SIRT1 and a PI3K inhibitor with IC50s of 2.4 μM, 3.0 […]
More Information Supplier PageQuercitrin (3-rhamnosyl quercetin, Sophoretin, Meletin, Xanthaurine), a glycoside of quercetin, has been found as a main bioactive constituent in T. sinensis leaves and has antioxidant, anti-inflammatory, and anti-allergic activities.
More Information Supplier PageQuetiapine(ICI204636) is an atypical antipsychotic used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.Quetiapine is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine is a dopamine receptor antagonist with a pIC50 of 6.33 for human D2 receptor. Quetiapine have moderate to high affinity for the human […]
More Information Supplier PageQuetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.
More Information Supplier PageQuetiapine Fumarate (ICI-204636) is an atypical antipsychotic used in the treatment of schizophrenia, bipolar I mania, bipolar II depression, bipolar I depression and shows affinity for various neurotransmitter receptors including serotonin, dopamine, histamine, and adrenergic receptors.
More Information Supplier PageQuetmolimab (Anti-CX3CL1 / Fractalkine) is a humanized monoclonal antibody targeting CX3CL1. MW: 150 KD.
More Information Supplier PageQuetmolimab (Anti-CX3CL1 / Fractalkine) is a humanized monoclonal antibody targeting CX3CL1. MW: 150 KD.
More Information Supplier PageQuetmolimab (Anti-CX3CL1 / Fractalkine) is a humanized monoclonal antibody targeting CX3CL1. MW: 150 KD.
More Information Supplier PageQuillaia Extract is extracted from Quillaja, which may be used as a foaming agent in soft drinks.
More Information Supplier PageQuillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol and shows strong anti-inflammatory activity.
More Information Supplier PageQuinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective phospholipase A2 inhibitor.
More Information Supplier PageQuinacrine 2HCl(Quinacrine dihydrochloride) is a lipophilic cationic drug with multiple actions that is commonly used as an anti-protozoal agent. Quinacrine is an effective phospholipase A2 inhibitor.
More Information Supplier PageQuinacrine (Mepacrine) is a dye of the acridine family that has been widely used as staining agents for DNA and model compounds for intercalators in numerous biophysical studies. It is also an antimalarial drug.
More Information Supplier PageQuinaldic acid is a product of l-tryptophan catabolism, via kynurenic acid, found in human urine.
More Information Supplier PageQuinapril HCl (CI-906, PD-109452-2) is the hydrochloride salt of quinapril that is an angiotensin-converting enzyme inhibitor with a Ki of 20 μM.
More Information Supplier PageQuinestrol (Ethinylestradiol 3-cyclopentyl ether, EE2CPE, W-3566) is a synthetic, steroidal estrogen which is used in hormone replacement therapy and occasionally to treat breast cancer and prostate cancer.
More Information Supplier PageQuinic acid (Chinic acid, Kinic acid) is a crystalline acid obtained from cinchona bark, coffee beans, and other plant products and made synthetically by hydrolysis of chlorogenic acid.
More Information Supplier PageQuinidine hemisulfate hydrate(Chinidin, Pitayine, β-quinine, (+)-quinidine) acts as a blocker of voltage-gated sodium channels, also an antimuscarinic and antimalarial.
More Information Supplier PageQuinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19.9 μM.
More Information Supplier PageQuinidine hydrochloride monohydrate is an anti-arrythmic agent and a potent potassium channel inhibitor with IC50 of 19.9 μM.
More Information Supplier PageQuinine, an alkaloid derived from the bark of the cinchona tree, is an anti-malaria agent and a potassium channel inhibitor that inhibits mSlo3 (KCa 5.1) channel currents evoked by voltage pulses to +100 mV with IC50 of 169 μM.
More Information Supplier PageQuinine HCl Dihydrate is a white crystalline K+ channel blocker, used to treat malaria.
More Information Supplier PageQuinizarin (1,4-Dihydroxyanthraquinone) is a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode. It is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.
More Information Supplier PageQuinizarin (1,4-Dihydroxyanthraquinone) is a part of the anticancer agents such as Doxorubicin, Daunorubicin, and Adriamycin, interacts with DNA by intercalating mode. It is used as a fungicide and pesticide chemical and has shown the ability to inhibit tumor cell growth.
More Information Supplier PageQuinoa Extract is extracted from Chenopodium quinoa Willd., which is used for the prevention and treatment of obesity and obesity-associated disorders.
More Information Supplier PageQuinocetone is a novel veterinary chemicals that is also bacteriocide and potential anti-tumor agent.
More Information Supplier PageQuinoline (1-Azanaphthalene, 1-Benzazine, Benzazabenzene, Benzopyridine) is a heterocyclic aromatic organic compound used in the manufacture of dyes, the preparation of hydroxyquinoline sulfate and niacin.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.
More Information Supplier PageQuinoline-4-carboxylic acid (4-Carboxyquinoline) is a very important structure in a synthetic medicinal chemistry.
More Information Supplier PageQuinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor.
More Information Supplier PageQuinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor.
More Information Supplier PageQuinupristin, a streptogramin antibiotic, blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits.
More Information Supplier PageQuisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
More Information Supplier PageQuisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
More Information Supplier PageQuisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
More Information Supplier PageQuisinostat (JNJ-26481585) 2HCl is a novel second-generation HDAC inhibitor with highest potency for HDAC1 with IC50 of 0.11 nM in a cell-free assay, modest potent to HDACs 2, 4, 10, and 11; greater than 30-fold selectivity against HDACs 3, 5, 8, and 9 and lowest potency to HDACs 6 and 7. Phase 2.
More Information Supplier PageQuizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.
More Information Supplier PageQuizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.
More Information Supplier PageQuizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Quizartinib (AC220) induces apoptosis of tumor cells. Phase 3.
More Information Supplier PageQX-314 chloride directly activates and permeates the human isoforms of TRPV1 and TRPA1 to induce inhibition of sodium channels.
More Information Supplier PageQX-314 chloride directly activates and permeates the human isoforms of TRPV1 and TRPA1 to induce inhibition of sodium channels.
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