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Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

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Onvansertib (NMS-P937) 10mM/1mL  | Purity Not Available

Selleck Chemicals

Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.

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Onvansertib (NMS-P937) 10mg  | Purity Not Available

Selleck Chemicals

Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.

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Onvansertib (NMS-P937) 50mg  | Purity Not Available

Selleck Chemicals

Onvansertib (NMS-P937, PCM-075, NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Onvansertib (NMS-P937) potently causes a mitotic cell-cycle arrest followed by apoptosis in cancer cell lines and inhibits tumor growth. Phase 1.

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Onvatilimab (Anti-B7-H5 / VISTA) 1mg  | Purity Not Available

Selleck Chemicals

Onvatilimab (Anti-B7-H5 / VISTA) is a human IgG1κ monoclonal antibody that targets and bind to VISTA (V-domain immunoglobulin (Ig) suppressor of T-cell activation). It has an anti-tumor activity. MW : 150 KD.

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Onvatilimab (Anti-B7-H5 / VISTA) 1mg*5  | Purity Not Available

Selleck Chemicals

Onvatilimab (Anti-B7-H5 / VISTA) is a human IgG1κ monoclonal antibody that targets and bind to VISTA (V-domain immunoglobulin (Ig) suppressor of T-cell activation). It has an anti-tumor activity. MW : 150 KD.

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Onvatilimab (Anti-B7-H5 / VISTA) 1mg*25  | Purity Not Available

Selleck Chemicals

Onvatilimab (Anti-B7-H5 / VISTA) is a human IgG1κ monoclonal antibody that targets and bind to VISTA (V-domain immunoglobulin (Ig) suppressor of T-cell activation). It has an anti-tumor activity. MW : 150 KD.

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ONX-0914 (PR-957) 25mg  | Purity Not Available

Selleck Chemicals

ONX-0914 (PR-957) is a potent and selective immunoproteasome inhibitor with minimal cross-reactivity for the constitutive proteasome in a cell-free assay.

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ONX-0914 (PR-957) 5mg  | Purity Not Available

Selleck Chemicals

ONX-0914 (PR-957) is a potent and selective immunoproteasome inhibitor with minimal cross-reactivity for the constitutive proteasome in a cell-free assay.

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ONX-0914 (PR-957) 10mM/1mL  | Purity Not Available

Selleck Chemicals

ONX-0914 (PR-957) is a potent and selective immunoproteasome inhibitor with minimal cross-reactivity for the constitutive proteasome in a cell-free assay.

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Oolong tea Extract 5mg  | Purity Not Available

Selleck Chemicals

Oolong Tea Extract is derived from semi-fermented green tea leaves, which includes antioxidants, minerals, vitamins, polyphenols, caffeine that have many health benefits.

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Opaganib (ABC294640) 5mg  | Purity Not Available

Selleck Chemicals

Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

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Opaganib (ABC294640) 25mg  | Purity Not Available

Selleck Chemicals

Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

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Opaganib (ABC294640) 100mg  | Purity Not Available

Selleck Chemicals

Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

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Opaganib (ABC294640) 1g  | Purity Not Available

Selleck Chemicals

Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

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Opaganib (ABC294640) 10mM/1mL  | Purity Not Available

Selleck Chemicals

Opaganib (ABC294640) is an orally bioavailable and selective sphingosine kinase-2 (SphK2) inhibitor with IC50 of approximately 60 μM. Phase 1/2.

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Opevesostat (ODM208) 5mg  | Purity Not Available

Selleck Chemicals

Opevesostat (ODM208) is the first-in-class, selective, nonsteroidal, oral CYP11A1 inhibitor. ODM208 exhibits a rapid, complete, durable, and reversible inhibition of the steroid hormone biosynthesis in an adrenocortical carcinoma cell model in vitro, in adult noncastrated male mice and dogs, and in patients with CRPC.

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Opevesostat (ODM208) 25mg  | Purity Not Available

Selleck Chemicals

Opevesostat (ODM208) is the first-in-class, selective, nonsteroidal, oral CYP11A1 inhibitor. ODM208 exhibits a rapid, complete, durable, and reversible inhibition of the steroid hormone biosynthesis in an adrenocortical carcinoma cell model in vitro, in adult noncastrated male mice and dogs, and in patients with CRPC.

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Ophiopogonin D 5mg  | Purity Not Available

Selleck Chemicals

Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) is a steroidal glycoside isolated from Chinese herb Radix ophiopogonis and shows anti-tumor property. Ophiopogonin D could suppress TGF-β1-mediated metastatic behavior of MDA-MB-231 cells by regulating ITGB1/FAK/Src/AKT/β-catenin/MMP-9 signaling axis. Ophiopogonin D attenuates PM2.5-induced inflammation via suppressing the AMPK/NF-κB pathway in mouse pulmonary epithelial cells.

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Ophiopogonin D 100mg  | Purity Not Available

Selleck Chemicals

Ophiopogonin D (OJV-VI, Deacetylophiopogonin C) is a steroidal glycoside isolated from Chinese herb Radix ophiopogonis and shows anti-tumor property. Ophiopogonin D could suppress TGF-β1-mediated metastatic behavior of MDA-MB-231 cells by regulating ITGB1/FAK/Src/AKT/β-catenin/MMP-9 signaling axis. Ophiopogonin D attenuates PM2.5-induced inflammation via suppressing the AMPK/NF-κB pathway in mouse pulmonary epithelial cells.

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Opicapone 100mg  | Purity Not Available

Selleck Chemicals

Opicapone(BIA 9-1067) is a potent inhibitor of catechol-O-methyltransferase (COMT) with ED50 values of 1.4 mg⋅kg−1 in rat erythrocytes. It has the potential to be used in research of Parkinson’s disease and motor fluctuations.

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Opicapone 5mg  | Purity Not Available

Selleck Chemicals

Opicapone(BIA 9-1067) is a potent inhibitor of catechol-O-methyltransferase (COMT) with ED50 values of 1.4 mg⋅kg−1 in rat erythrocytes. It has the potential to be used in research of Parkinson’s disease and motor fluctuations.

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Opicapone 25mg  | Purity Not Available

Selleck Chemicals

Opicapone(BIA 9-1067) is a potent inhibitor of catechol-O-methyltransferase (COMT) with ED50 values of 1.4 mg⋅kg−1 in rat erythrocytes. It has the potential to be used in research of Parkinson’s disease and motor fluctuations.

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Opicinumab (Anti-LINGO1) 1mg  | Purity Not Available

Selleck Chemicals

Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential applications in acute optic neuritis and relapsed multiple sclerosis. MW: 145.5 kD.

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Opicinumab (Anti-LINGO1) 1mg*5  | Purity Not Available

Selleck Chemicals

Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential applications in acute optic neuritis and relapsed multiple sclerosis. MW: 145.5 kD.

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Opicinumab (Anti-LINGO1) 1mg*25  | Purity Not Available

Selleck Chemicals

Opicinumab (BIIB033) is a monoclonal antibody against LINGO-1 and has potential applications in acute optic neuritis and relapsed multiple sclerosis. MW: 145.5 kD.

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Opnurasib (JDQ-443) 5mg  | Purity Not Available

Selleck Chemicals

Opnurasib (JDQ-443,NVP-JDQ443) , a potent and selective, orally bioavailable covalent inhibitor of GDP-bound KRASG12C with an IC50 of 0.012 µM for inhibition of c-Raf recruitment.

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Opnurasib (JDQ-443) 25mg  | Purity Not Available

Selleck Chemicals

Opnurasib (JDQ-443,NVP-JDQ443) , a potent and selective, orally bioavailable covalent inhibitor of GDP-bound KRASG12C with an IC50 of 0.012 µM for inhibition of c-Raf recruitment.

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Opnurasib (JDQ-443) 100mg  | Purity Not Available

Selleck Chemicals

Opnurasib (JDQ-443,NVP-JDQ443) , a potent and selective, orally bioavailable covalent inhibitor of GDP-bound KRASG12C with an IC50 of 0.012 µM for inhibition of c-Raf recruitment.

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Opoponax oil 500mg  | Purity Not Available

Selleck Chemicals

Opoponax oil is isolated and extracted from Commiphora erythraea (opoponax), with a promising insecticidal property.

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Oportuzumab (Anti-EpCAM / TROP1 / CD326) 1mg  | Purity Not Available

Selleck Chemicals

Oportuzumab (Anti-EpCAM / TROP1 / CD326) is a humanized monoclonal antibody targeting EpCAM. It exhibits potential in treatment of bacillus Calmette-Guérin refractory carcinoma in situ of the bladder. MW :145.4 KD.

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Oportuzumab (Anti-EpCAM / TROP1 / CD326) 1mg*5  | Purity Not Available

Selleck Chemicals

Oportuzumab (Anti-EpCAM / TROP1 / CD326) is a humanized monoclonal antibody targeting EpCAM. It exhibits potential in treatment of bacillus Calmette-Guérin refractory carcinoma in situ of the bladder. MW :145.4 KD.

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Oportuzumab (Anti-EpCAM / TROP1 / CD326) 1mg*25  | Purity Not Available

Selleck Chemicals

Oportuzumab (Anti-EpCAM / TROP1 / CD326) is a humanized monoclonal antibody targeting EpCAM. It exhibits potential in treatment of bacillus Calmette-Guérin refractory carcinoma in situ of the bladder. MW :145.4 KD.

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Oprozomib 5mg  | Purity Not Available

Selleck Chemicals

Oprozomib is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.

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Oprozomib 50mg  | Purity Not Available

Selleck Chemicals

Oprozomib is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.

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Oprozomib 10mM/1mL  | Purity Not Available

Selleck Chemicals

Oprozomib is an orally bioavailable inhibitor for CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM. Phase 1/2.

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Orantinib (SU6668) 5mg  | Purity Not Available

Selleck Chemicals

Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.

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Orantinib (SU6668) 10mM/1mL  | Purity Not Available

Selleck Chemicals

Orantinib (TSU-68, SU6668) has greatest potency against PDGFR autophosphorylation with Ki of 8 nM in a cell-free assay, but also strongly inhibits Flk-1 and FGFR1 trans-phosphorylation, little activity against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2; does not inhibit EGFR. Phase 3.

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Orcinol 25mg  | Purity Not Available

Selleck Chemicals

Orcinol (5-Methylresorcinol; 3,5-ToluenediolOrcin; 5-Methyl-1,3-benzenediol; 3,5-Dihydroxytoluene), occurs in many species of lichens including Roccella tinctoria and Lecanora, exhibits antimutagenic, antioxidant, antibacterial, radical-scavenging effects.

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Orcinol glucoside 5mg  | Purity Not Available

Selleck Chemicals

Orcinol glucoside (OG, Sakakin) is an active constituent isolated from the rhizomes of Curculigo orchioides Gaertn. It shows potent antioxidative and anxiolytic activities without sedative effects.

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Ordesekimab (Anti-IL-15) 1mg  | Purity Not Available

Selleck Chemicals

Ordesekimab (Anti-IL-15) is a fully human monoclonal antibody targeting IL-15 and inhibiting the interaction of IL-15 with the IL-2Rβ. It has the potential for treatment of nonresponsive celiac disease (NRCD). MW :143.82 KD.

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Ordesekimab (Anti-IL-15) 1mg*5  | Purity Not Available

Selleck Chemicals

Ordesekimab (Anti-IL-15) is a fully human monoclonal antibody targeting IL-15 and inhibiting the interaction of IL-15 with the IL-2Rβ. It has the potential for treatment of nonresponsive celiac disease (NRCD). MW :143.82 KD.

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Ordesekimab (Anti-IL-15) 1mg*25  | Purity Not Available

Selleck Chemicals

Ordesekimab (Anti-IL-15) is a fully human monoclonal antibody targeting IL-15 and inhibiting the interaction of IL-15 with the IL-2Rβ. It has the potential for treatment of nonresponsive celiac disease (NRCD). MW :143.82 KD.

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Oregano Extract 5mg  | Purity Not Available

Selleck Chemicals

Oregano Extract is extracted from Origanum vulgare, which has benefits for cardiovascular protection, cancer prevention, and lowers gastrointestinal inflammation.

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