Selleck Chemicals

Selleck Chemicals logo

Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

Company Website

Product Listing

Jujubae Fructus Extract 5mg  | Purity Not Available

Selleck Chemicals

Jujubae Fructus Extract is extracted from fruit of Ziziphus jujuba Mill, which provides an effective treatment for chronic constipation and type 2 diabetes.

More Information Supplier Page

Jujuboside A 5mg  | Purity Not Available

Selleck Chemicals

Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis.

More Information Supplier Page

Jujuboside A 1mg  | Purity Not Available

Selleck Chemicals

Jujuboside A, isolated from Semen Ziziphi Spinosae, exerts anti-oxidant, anti-inflammatory activities, and reduces the cell apoptosis.

More Information Supplier Page

Jujuboside B 1mg  | Purity Not Available

Selleck Chemicals

Jujuboside B, one of the saponins isolated from the seeds of Zizyphus jujuba var. spinosa, is used in traditional chinese medicine for treating cardiovascular diseases and neurodegenerative diseases.

More Information Supplier Page

Junci Medulla Extract 5mg  | Purity Not Available

Selleck Chemicals

Junci Medulla Extract is extracted from Junci Medulla that promotes urination, leaches out dampness and unblocks painful urinary dysfunction, cools the blood and stops bleeding.

More Information Supplier Page

Juniper Berry Extract 5mg  | Purity Not Available

Selleck Chemicals

Juniper Berry Extract is extracted from the fruit of Juniperus communis L., and acts as a chemopreventive dietary agent, inhibiting cell proliferation and inducing apoptosis, which reduces the formation of colon tumours.

More Information Supplier Page

Justicia Gendarussa Extract 5mg  | Purity Not Available

Selleck Chemicals

Justicia Gendarussa Extract is obtained from Justicia gendarussa, which is useful in asthma, rheumatism and colics of children, also may have the potential to be the basis for a birth control pill for men.

More Information Supplier Page

JW55 5mg  | Purity Not Available

Selleck Chemicals

JW55 is a potent and selective inhibitor of the canonical Wnt pathway that functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).

More Information Supplier Page

JW55 25mg  | Purity Not Available

Selleck Chemicals

JW55 is a potent and selective inhibitor of the canonical Wnt pathway that functions via inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2).

More Information Supplier Page

JW642 5mg  | Purity Not Available

Selleck Chemicals

JW642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.

More Information Supplier Page

JW642 25mg  | Purity Not Available

Selleck Chemicals

JW642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.

More Information Supplier Page

JW74 5mg  | Purity Not Available

Selleck Chemicals

JW74 is a specific inhibitor of the canonical Wnt signaling with IC50 790 nM in the ST-Luc assay. It inhibit the growth of tumor cells in both mouse xenograft model of colorectal cancer and in ApcMin mice.

More Information Supplier Page

JW74 25mg  | Purity Not Available

Selleck Chemicals

JW74 is a specific inhibitor of the canonical Wnt signaling with IC50 790 nM in the ST-Luc assay. It inhibit the growth of tumor cells in both mouse xenograft model of colorectal cancer and in ApcMin mice.

More Information Supplier Page

JX06 25mg  | Purity Not Available

Selleck Chemicals

JX06 is a selective covalent inhibitor of PDK1 in cells. JX06 dose-dependently inhibits PDK1, PDK2 and PDK3 with IC50 0.049 μM, 0.101 μM and 0.313 μM, respectively.

More Information Supplier Page

JX06 5mg  | Purity Not Available

Selleck Chemicals

JX06 is a selective covalent inhibitor of PDK1 in cells. JX06 dose-dependently inhibits PDK1, PDK2 and PDK3 with IC50 0.049 μM, 0.101 μM and 0.313 μM, respectively.

More Information Supplier Page

JZL184 50mg  | Purity Not Available

Selleck Chemicals

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

More Information Supplier Page

JZL184 10mg  | Purity Not Available

Selleck Chemicals

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

More Information Supplier Page

JZL184 1g  | Purity Not Available

Selleck Chemicals

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

More Information Supplier Page

JZL184 10mM/1mL  | Purity Not Available

Selleck Chemicals

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

More Information Supplier Page

JZL195 5mg  | Purity Not Available

Selleck Chemicals

JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.

More Information Supplier Page

K 858 5mg  | Purity Not Available

Selleck Chemicals

K858 is a novel and potent inhibitor of Eg5 with an IC50 of 1.3 μM for inhibiting the ATPase activity of Eg5, showing at least 150-fold more selective for Eg5 than other members of the kinesin superfamily.

More Information Supplier Page

K-604 dihydrochloride 5mg  | Purity Not Available

Selleck Chemicals

K-604 dihydrochloride, a potent and selective inhibitor of Acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1), suppresses the development of atherosclerosis in an animal model without affecting plasma cholesterol levels.

More Information Supplier Page

K-975 5mg  | Purity Not Available

Selleck Chemicals

K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma.

More Information Supplier Page

K-975 25mg  | Purity Not Available

Selleck Chemicals

K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma.

More Information Supplier Page

K-975 100mg  | Purity Not Available

Selleck Chemicals

K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma.

More Information Supplier Page

K-975 1g  | Purity Not Available

Selleck Chemicals

K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma.

More Information Supplier Page

K-975 10mM/1mL  | Purity Not Available

Selleck Chemicals

K-975 is a potent, selective and orally active TEAD inhibitor that directly inhibits YAP/TAZ-TEAD protein-protein interaction and shows a potent anti-tumor effect in malignant pleural mesothelioma.

More Information Supplier Page

K-Ras-IN-1 25mg  | Purity Not Available

Selleck Chemicals

K-Ras-IN-1 (MDK-3017) inhibits K-Ras by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.

More Information Supplier Page

K-Ras-IN-1 5mg  | Purity Not Available

Selleck Chemicals

K-Ras-IN-1 (MDK-3017) inhibits K-Ras by binding to K-Ras in a hydrophobic pocket that is occupied by Tyr-71 in the apo-Ras crystal structure.

More Information Supplier Page

K02288 1g  | Purity Not Available

Selleck Chemicals

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

More Information Supplier Page

K02288 10mM/1mL  | Purity Not Available

Selleck Chemicals

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

More Information Supplier Page

K02288 10mg  | Purity Not Available

Selleck Chemicals

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

More Information Supplier Page

K02288 50mg  | Purity Not Available

Selleck Chemicals

K02288 is a potent, and selective type I BMP receptor inhibitor with IC50 of 1.1, 1.8, 6.4 nM for ALK2, ALK1 and ALK6, showing weaker inhibition on other ALKs (3, 4, 5) and ActRIIA.

More Information Supplier Page

K03861 (AUZ454) 5mg  | Purity Not Available

Selleck Chemicals

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

More Information Supplier Page

K03861 (AUZ454) 25mg  | Purity Not Available

Selleck Chemicals

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

More Information Supplier Page

K03861 (AUZ454) 100mg  | Purity Not Available

Selleck Chemicals

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

More Information Supplier Page

K03861 (AUZ454) 1g  | Purity Not Available

Selleck Chemicals

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

More Information Supplier Page

K03861 (AUZ454) 10mM/1mL  | Purity Not Available

Selleck Chemicals

K03861 (AUZ454) is a type II CDK2 inhibitor with Kd of 50 nM, 18.6 nM, 15.4 nM, and 9.7 nM for CDK2(WT), CDK2(C118L), CDK2(A144C), and CDK2(C118L/A144C), respectlvely.

More Information Supplier Page

K145 5mg  | Purity Not Available

Selleck Chemicals

K145 is a selective, substrate-competitive and orally active sphingosine kinase-2 (SphK2) inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM in biochemical assays.

More Information Supplier Page

K145 25mg  | Purity Not Available

Selleck Chemicals

K145 is a selective, substrate-competitive and orally active sphingosine kinase-2 (SphK2) inhibitor with an IC50 of 4.3 µM and a Ki of 6.4 µM in biochemical assays.

More Information Supplier Page

K6PC-5 5mg  | Purity Not Available

Selleck Chemicals

K6PC-5, a ceramide derivative, is a sphingosine kinase 1 (SPHK1) activator and elicits a rapid transient increase in intracellular calcium levels.

More Information Supplier Page

K6PC-5 25mg  | Purity Not Available

Selleck Chemicals

K6PC-5, a ceramide derivative, is a sphingosine kinase 1 (SPHK1) activator and elicits a rapid transient increase in intracellular calcium levels.

More Information Supplier Page

KA2507 5mg  | Purity Not Available

Selleck Chemicals

KA2507, a potent, orally active and selective HDAC6 inhibitor with IC50 of 2.5 nM, shows antitumor activities and immune modulatory effects in preclinical models.

More Information Supplier Page

KA2507 25mg  | Purity Not Available

Selleck Chemicals

KA2507, a potent, orally active and selective HDAC6 inhibitor with IC50 of 2.5 nM, shows antitumor activities and immune modulatory effects in preclinical models.

More Information Supplier Page