Ac-YVAD-cmk (Caspase-1 Inhibitor II) is a selective IL-1β converting enzyme (ICE) inhibitor with neuroprotective and anti-inflammatory effects, effectively suppresses the expression of IL-1β and IL-18.

AC1903 (compound 2) is a specific and selective TRPC5 (transient receptor potential canonical channel 5) inhibitor with IC50 of 4.06 μM.

AC1903 (compound 2) is a specific and selective TRPC5 (transient receptor potential canonical channel 5) inhibitor with IC50 of 4.06 μM.

AC480 (BMS-599626) is a selective and efficacious inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM, ~8-fold less potent to HER4, >100-fold to VEGFR2, c-Kit, Lck, MET etc. Phase 1.

Acacetin (Linarigenin, 5,7-dihydroxy-4′-methoxyflavone, 4′-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.

Acacetin (Linarigenin, 5,7-dihydroxy-4′-methoxyflavone, 4′-Methoxyapigenin) is a flavonoid compound that has been shown to have anti-cancer, anti-mutagenic, anti-inflammatory and anti-peroxidative effects.

Acalabrutinib (ACP-196) is a selective second-generation Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, […]

Acalabrutinib (ACP-196) is a selective second-generation Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, […]

Acalabrutinib (ACP-196) is a selective second-generation Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, […]

Acalabrutinib (ACP-196) is a selective second-generation Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, […]

Acalabrutinib (ACP-196) is a selective second-generation Bruton’s tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity over ibrutinib with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, […]

Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.

Acalisib (GS-9820, CAL-120) is a highly selective and potent p110δ inhibitor (IC50 = 14 nM) with 114- to 400-fold selectivity over the other class I PI3K enzymes and no activity against Class II and III PI3K family members or other PI3K-related proteins including mTOR and DNA-PK.

Acamprosate (N-Acetylhomotaurine, Calcium acetylhomotaurinate,N-acetylhomotaurinate) is a synthetic compound with a chemical structure similar to the amino acid neurotransmitter gamma-aminobutyric acid (GABA) and the amino acid neuromodulator taurine.

Acamprosate (N-Acetylhomotaurine, Calcium acetylhomotaurinate,N-acetylhomotaurinate) is a synthetic compound with a chemical structure similar to the amino acid neurotransmitter gamma-aminobutyric acid (GABA) and the amino acid neuromodulator taurine.

Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.

Acarbose(BAY g 5421,Prandase, Precose, Glucobay, Bay-g 5421) is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.

ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis.

Acebutolol is a β-adrenergic receptors antagonist used in the treatment of hypertension, angina pectoris and cardiac arrhythmias.

Aceclofenac (Preservex, Airtal) is a non-steroidal anti-inflammatory drug (NSAID) with anti-inflammatory and analgesic properties.

Aceglutamide (α-N-Acetyl-L-glutamine, N2-Acetylglutamine) is a psychostimulant, nootropic agent which functions as a prodrug to glutamine with improved potency and stability.

Acelarin (NUC-1031, CPF-31, MTL-007, GTPL7389) is a DNA synthesis inhibitor with EC50 of 0.2 nM.

Acelarin (NUC-1031, CPF-31, MTL-007, GTPL7389) is a DNA synthesis inhibitor with EC50 of 0.2 nM.

Acetamide (ethanamide, Acetic acid amide) is an organic compound that can be used as a plasticizer and an industrial solvent.

Acetanilide(Antifebrin,N-phenylacetamide, Acetanil, Acetamidobenzene, Acetylaniline, NSC 7636) is an aniline derivative and has possess analgesic.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.

Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).

Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).

Acetazolamide (Diamox), a potent carbonic anhydrase (CA) inhibitor, is commonly used in clinical practice as an immediate and readily available option for acute reduction of intraocular pressure(IOP).

Acetic acid octyl ester (Octyl acetate) is one of the major components of essential oils in the vittae, or oil tubes, of the wild parsnip (Pastinaca sativa). Acetic acid octyl ester exhibits antioxidant activity.

Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.

Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea with hypoglycemic activity. It exerts the blood-glucose-lowering effects by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently.

Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.

Acetohydroxamic acid is an Urease Inhibitor. In the urine, it acts as an antagonist of the bacterial enzyme urease.

Acetoin is an important physiological metabolite excreted by many microorganisms. It is widely used in food and cosmetic industry as taste and fragrance enhancer.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing.

Acetophenone (Methyl phenyl ketone, Phenylethanone) is an organic compound used as fragrances and a raw material for the synthesis of some pharmaceuticals.

Acetophenone (Methyl phenyl ketone, Phenylethanone) is an organic compound used as fragrances and a raw material for the synthesis of some pharmaceuticals.