Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteGarivulimab (Anti-B7-H1 / PD-L1 / CD274) is a humanized immunoglobulin G1 (IgG1)-variant monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 144.3 KD.
More Information Supplier PageGarivulimab (Anti-B7-H1 / PD-L1 / CD274) is a humanized immunoglobulin G1 (IgG1)-variant monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW: 144.3 KD.
More Information Supplier PageGarlic chives Extract is extracted from Allium tuberosum, which provides a new therapeutic in the treatment of NLRP3 inflammasome-driven diseases.
More Information Supplier PageGarlic Extract is extracted from Allium sativum, which has anti-hypertensive, anti-hyperlipidemic, and hypoglycemic effects.
More Information Supplier PageGarlic Extract (1%) is extracted from Allium sativum, which can be used in the treatment of conventional antihypertensive therapy.
More Information Supplier PageGarlic oil blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis by inducing phase II drug-metabolizing enzymes.
More Information Supplier PageGarsorasib (D-1553 ) is a potent and selective oral KRASG12C inhibitor with antitumor activity. It has the potential to treat KRAS G12C-mutated non-small cell lung cancer (NSCLC).
More Information Supplier PageGarsorasib (D-1553 ) is a potent and selective oral KRASG12C inhibitor with antitumor activity. It has the potential to treat KRAS G12C-mutated non-small cell lung cancer (NSCLC).
More Information Supplier PageGastrin Tetrapeptide (Cholecystokinin tetrapeptide, tetragastrin, CCK-4) is the C-terminal tetrapeptide of gastrin, can stimulate gastric secretion, also is a cholecystokinin (CCK)-4 receptor agonist, with the effect of gastric mucosal protection.
More Information Supplier PageGastrodenol (Bismuth tripotassium dicitrate) is used to treat certain conditions caused by too much acid being produced in the stomach, such as stomach ulcers and ulcers of the upper part of the intestine (duodenal ulcers).
More Information Supplier PageGastrodenol (Bismuth tripotassium dicitrate) is used to treat certain conditions caused by too much acid being produced in the stomach, such as stomach ulcers and ulcers of the upper part of the intestine (duodenal ulcers).
More Information Supplier PageGastrodia Rhizome Extract is derived from the rhizome of Gastrodia elata Blume, which is extensively used in traditional Chinese herbal medicine to treat brain-related diseases (e.g., headache, migraine, dizziness, epilepsy, infantile convulsion, Alzheimer’s disease, and stroke).
More Information Supplier PageGastrodin (Gastrodine), an anti-inflammatory polyphenol extracted from Chinese natural herbal Gastrodia elata Blume., benefits neurodegenerative diseases.
More Information Supplier PageGatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase andtopoisomerase IV.
More Information Supplier PageGatifloxacin (AM-1155, CG5501, BMS-206584) is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase andtopoisomerase IV.
More Information Supplier PageGatifloxacin (AM-1155, CG5501, BMS-206584, PD135432) hydrochloride is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases with IC50 of 13.8 μg/ml and 0.109 μg/ml for S. aureus topoisomerase IV and E. coli DNA gyrase, respectively.
More Information Supplier PageGatipotuzumab (Anti-MUC1) is a humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1) with potential antineoplastic activity. MW: 146.58 KD.
More Information Supplier PageGatipotuzumab (Anti-MUC1) is a humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1) with potential antineoplastic activity. MW: 146.58 KD.
More Information Supplier PageGatipotuzumab (Anti-MUC1) is a humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1) with potential antineoplastic activity. MW: 146.58 KD.
More Information Supplier PageGatralimab (Anti-CD52) is an IgG1 anti-CD52 monoclonal antibody with the potential to treat Symptomatic Osteoarthritis. MW : 145.0 KD.
More Information Supplier PageGatralimab (Anti-CD52) is an IgG1 anti-CD52 monoclonal antibody with the potential to treat Symptomatic Osteoarthritis. MW : 145.0 KD.
More Information Supplier PageGatralimab (Anti-CD52) is an IgG1 anti-CD52 monoclonal antibody with the potential to treat Symptomatic Osteoarthritis. MW : 145.0 KD.
More Information Supplier PageGB1107 is a potent, selective, inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3.
More Information Supplier PageGB1107 is a potent, selective, inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3.
More Information Supplier PageGB1107 is a potent, selective, inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3.
More Information Supplier PageGboxin is an inhibitor of oxidative phosphorylation in cancer cells. Gboxin inhibits the activity of F0F1 ATP synthase. It specifically inhibits the growth of primary mouse and human glioblastoma cells but not that of mouse embryonic fibroblasts or neonatal astrocytes.
More Information Supplier PageGboxin is an inhibitor of oxidative phosphorylation in cancer cells. Gboxin inhibits the activity of F0F1 ATP synthase. It specifically inhibits the growth of primary mouse and human glioblastoma cells but not that of mouse embryonic fibroblasts or neonatal astrocytes.
More Information Supplier PageGC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
More Information Supplier PageGC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
More Information Supplier PageGC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
More Information Supplier PageGC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
More Information Supplier PageGC376 is a 3CLpro (3C-like protease) inhibitor with IC50 of ~ 1.11 μM for the PEDV 3CLpro. GC376 is active against the 3CLpro of multiple coronaviruses, including SARS-CoV.
More Information Supplier PageGC7 (N1-guanyl-1,7-diaminoheptane) Sulfate is an inhibitor of deoxyhypusine synthase (DHPS). GC7 inhibits Neuroblastoma (NB) cell proliferation in a dose-dependent manner, through induction of the cell cycle inhibitor p21 and reduction of total and phosphorylated Rb proteins.
More Information Supplier PageGC7 (N1-guanyl-1,7-diaminoheptane) Sulfate is an inhibitor of deoxyhypusine synthase (DHPS). GC7 inhibits Neuroblastoma (NB) cell proliferation in a dose-dependent manner, through induction of the cell cycle inhibitor p21 and reduction of total and phosphorylated Rb proteins.
More Information Supplier PageGCN2iB is an ATP-competitive serine/threonine-protein kinase general control nonderepressible 2 (GCN2) inhibitor with IC50 of 2.4 nM.
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GCN2iB is an ATP-competitive serine/threonine-protein kinase general control nonderepressible 2 (GCN2) inhibitor with IC50 of 2.4 nM.
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GCN2iB is an ATP-competitive serine/threonine-protein kinase general control nonderepressible 2 (GCN2) inhibitor with IC50 of 2.4 nM.
More Information Supplier PageGCN2iB is an ATP-competitive serine/threonine-protein kinase general control nonderepressible 2 (GCN2) inhibitor with IC50 of 2.4 nM.
More Information Supplier PageGDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
More Information Supplier PageGDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
More Information Supplier PageGDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
More Information Supplier PageGDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM in cell-free assays, respectively; less affinity shown to cIAP1-BIR2 and cIAP2-BIR2. Phase 1.
More Information Supplier PageGDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.
More Information Supplier PageGDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.
More Information Supplier PageGDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.
More Information Supplier PageGDC-0326 is a potent and selective inhibitor of PI3Kα with Ki value of 0.2 nM; remarkably selective over the other class I isoforms in enzymatic assays.
More Information Supplier PageGDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
More Information Supplier PageGDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
More Information Supplier PageGDC-0575 is a potent and selective CHK1 inhibitor with an IC50 of 1.2 nM.
More Information Supplier PageGDC-0575 is a potent and selective CHK1 inhibitor with an IC50 of 1.2 nM.
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