Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteA unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD).
More Information Supplier PageFramycetin sulfate (Neomycin B sulfate), an aminoglycoside antibiotic, is a potent RNase P cleavage activity inhibitor with a Ki of 35 μM, and competes for specific divalent metal ion binding sites in RNase P RNA, also inhibits hammerhead ribozyme with a Ki of 13.5 μM.
More Information Supplier PageFRAX-1036 is a potent and selective PAK inhibitor with biochemical potency (Ki) of 23.3 nM and 72.4 nM against PAK1 and PAK2.
More Information Supplier PageFRAX-1036 is a potent and selective PAK inhibitor with biochemical potency (Ki) of 23.3 nM and 72.4 nM against PAK1 and PAK2.
More Information Supplier PageFRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
More Information Supplier PageFRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
More Information Supplier PageFRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
More Information Supplier PageFRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.
More Information Supplier PageFRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.
More Information Supplier PageFRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.
More Information Supplier PageFRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.
More Information Supplier PageFRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.
More Information Supplier PageFraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
More Information Supplier PageFraxetin (7,8-dihydroxy-6-methoxy coumarin), found in Fraxinus rhynchophylla, shows potent antioxidant activity.fraxetin alleviates lipid peroxidation, enhances hepatic antioxidant capabilities, inhibits CYP2E1 activity, and reduced the inflammatory mediators, including TNF-α and IL-1β via up-regulation of hemeoxygenase-1 (HO-1) protein.
More Information Supplier PageFraxin (Fraxetin-8-O-glucoside), a main active component isolated from Cortex Fraxini, possesses a variety of bioactivities such as anti-inflammatory, antioxidant, analgesic, antimicrobial, antiviral, immunomodulatory, anti-hyperuricemia and diuresis.
More Information Supplier PageFraxinellone is a natural product isolated from the D. dasycarpus plant, which has been shown to exhibit neuroprotective and anti-inflammatory activities.
More Information Supplier PageFremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.
More Information Supplier PageFremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.
More Information Supplier PageFremanezumab (Anti-CALCA / CGRP) is a humanized IgG2a monoclonal antibody that selectively and potently targets calcitonin gene-related peptide (CGRP). Fremanezumab has the potential for chronic migraine research.. MW: 145.5 kD.
More Information Supplier PageFrentizole (Frentizol) is a novel inhibitor of amyloid beta peptide (Abeta) binding alcohol dehydrogenase (ABAD) interaction with IC50 of 200 μM. Frentizole is a nontoxic antiviral and immunosuppressive agent used clinically in rheumatoid arthritis and systemic lupus erythematosus.
More Information Supplier PageFresolimumab (Anti-TGFb1) is a pan-specific, recombinant, fully human monoclonal antibody directed against human transforming growth factor (TGF) beta 1, 2, and 3 with potential antineoplastic activity. MW : 145.5 KD.
More Information Supplier PageFresolimumab (Anti-TGFb1) is a pan-specific, recombinant, fully human monoclonal antibody directed against human transforming growth factor (TGF) beta 1, 2, and 3 with potential antineoplastic activity. MW : 145.5 KD.
More Information Supplier PageFresolimumab (Anti-TGFb1) is a pan-specific, recombinant, fully human monoclonal antibody directed against human transforming growth factor (TGF) beta 1, 2, and 3 with potential antineoplastic activity. MW : 145.5 KD.
More Information Supplier PageFringed Pink Extract is extracted from Dianthus superbus, which has anti-inflammatory activity.
More Information Supplier PageFritillaria Cirrhosa Seed Extract is extracted from the seeds of Fritillaria Cirrhosa, which is famous for its antitussive, expectorant, anti-asthma and anti-inflammatory properties, and is widely used to treat respiratory diseases.
More Information Supplier PageFritillariae Cirrhosae Bulbus Extract is obtained from Fritillariae cirrhosae, mediates apoptosis through a STAT1 and STAT4-mediated co-regulatory network, which may be the key novel mechanism for its antitumor activity.
More Information Supplier PageFritillariae Thunbergii Bulbus Extract is extracted from Fritillariae thunbergii bulbus, which is used to treat symptoms of cough and airway congestion in the chest due to pathological colds and damp phlegm.
More Information Supplier PageFrovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
More Information Supplier PageFrovatriptan Succinate(SB 209509 Succinate,VML 251 Succinate) is the succinate salt form of frovatriptan, a synthetic triptan with serotonin (5-HT) receptor agonist activity especially for the 5-HT1B/1D receptors.
More Information Supplier PageFrovocimab (Anti-PCSK9) is a humanized IgG4 monoclonal antibody that neutralizes proprotein convertase subtilisin-kexin type 9 (PCSK9). MW: 146.88 KD.
More Information Supplier PageFrovocimab (Anti-PCSK9) is a humanized IgG4 monoclonal antibody that neutralizes proprotein convertase subtilisin-kexin type 9 (PCSK9). MW: 146.88 KD.
More Information Supplier PageFrovocimab (Anti-PCSK9) is a humanized IgG4 monoclonal antibody that neutralizes proprotein convertase subtilisin-kexin type 9 (PCSK9). MW: 146.88 KD.
More Information Supplier PageFructose (D-(-)-Fructose, Fruit sugar, levulose, fructosteril, D-fructofuranose, D-arabino-hexulose) is a simple ketonic monosaccharide found in many plants.
More Information Supplier PageFructus Akebiae Extract is extracted from Fructus akebiae, which is used for the treatment of mental disorders.
More Information Supplier PageFructus Anisi Stellati Extract is extracted from the fruit of Illicium verum, which involves in signalling pathways that target cancer cell apoptosis, proliferation, and tumour metastasis in Gastric cancer cells.
More Information Supplier PageFructus Chebulae Extract is extracted from the mature fruit of Terminalia chebula Retz., which can rescue neuronal cell death against ischemia-related damage.
More Information Supplier PageFructus mume Extract is obtained from the processed fruit of Fructus mume Sieb. et Zucc., which effectively improves cognitive impairment in familial Alzheimer’s disease, scopolamine-induced memory impairment, and chronic cerebral hypoperfusion-induced cognitive impairment.
More Information Supplier PageFruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
More Information Supplier PageFruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
More Information Supplier PageFruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
More Information Supplier PageFSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. It triggers iron death in cancer cells by inhibiting FSP1 and can be used in research of cancer.
More Information Supplier PageFSEN1 is a potent and non-competitive FSP1 inhibitor with an IC50 value of 313 nM. It triggers iron death in cancer cells by inhibiting FSP1 and can be used in research of cancer.
More Information Supplier PageFSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
More Information Supplier PageFSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
More Information Supplier PageFSL-1, a bacterial-derived toll-like receptor 2/6 (TLR2/6) agonist, enhances resistance to experimental HSV-2 infection.
More Information Supplier PageFSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
More Information Supplier PageFSLLRY-NH2 TFA (FSY-NH2) is a selective protease-activated receptor 2 (PAR2) inhibitor with an ic50 of 50 µM in PAR2-KNRK cells.
More Information Supplier PageFT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM.
More Information Supplier PageFT113 is a potent inhibitor of fatty acid synthase (FAS/FASN) with ic50 of 213 nM.
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