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Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.

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5′-Cytidylic acid 25mg  | Purity Not Available

Selleck Chemicals

5′-Cytidylic acid (Cytidine monophosphate, Cytidine 5′-phosphate) is a nucleotide that is used as a monomer in RNA.

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5′-Deoxy-5′-(methylthio)adenosine 25mg  | Purity Not Available

Selleck Chemicals

5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of 0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively.

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5′-Deoxy-5′-(methylthio)adenosine 100mg  | Purity Not Available

Selleck Chemicals

5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine, MTA) is a naturally occurring sulfur-containing nucleoside produced by the decarboxylation of S-adenosylmethionine. This nucleoside is a potent agonist of adenosine receptors with Ki of 0.15, 1.13, 13.9, and 0.68 μM for A1, A2A, A2B, and A3, respectively.

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5′-N-Ethylcarboxamidoadenosine (NECA) 5mg  | Purity Not Available

Selleck Chemicals

5′-N-Ethylcarboxamidoadenosine (NECA, 5′-(N-Ethylcarboxamido)adenosine, Adenosine-5’N-ethylcarboxamide, 5′-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5′-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54)), and blocking activation of the JNK-MAPK pathway.

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5′-N-Ethylcarboxamidoadenosine (NECA) 25mg  | Purity Not Available

Selleck Chemicals

5′-N-Ethylcarboxamidoadenosine (NECA, 5′-(N-Ethylcarboxamido)adenosine, Adenosine-5’N-ethylcarboxamide, 5′-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5′-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54)), and blocking activation of the JNK-MAPK pathway.

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5′-N-Ethylcarboxamidoadenosine (NECA) 10mM/1mL  | Purity Not Available

Selleck Chemicals

5′-N-Ethylcarboxamidoadenosine (NECA, 5′-(N-Ethylcarboxamido)adenosine, Adenosine-5’N-ethylcarboxamide, 5′-Ethylcarboxamidoadenosine) is a stable, nonselective adenosine receptor agonist. 5′-N-Ethylcarboxamidoadenosine acts via multiple mechanisms including: reducing diabetes-induced oxidative stress, inhibiting gene expression of IL-18, TNF-α and ICAM-1 (intercellular adhesion molecule 1 (CD54)), and blocking activation of the JNK-MAPK pathway.

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5% Artichoke Leaf EXTRACT 5mg  | Purity Not Available

Selleck Chemicals

5% Artichoke Leaf EXTRACT is extracted from Cynara scolymus, which has antioxidant, choleretic, hepatoprotective, bile-enhancing, and lipid-lowering effects.

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5a-Pregnane-3,20-dione 100mg  | Purity Not Available

Selleck Chemicals

5a-Pregnane-3,20-dione (5alphaP, 5-a-dihydroprogesterone, 3,20-allopregnanedione, 5-Alpha-Dihydro Progesterone) is the endogenous progesterone metabolite. 5a-Pregnane-3,20-dione depolymerizes actin and decreases expression of actin and vinculin. 5a-Pregnane-3,20-dione is involved in promoting breast neoplasia and metastasis by affecting adhesion and cytoskeletal molecules.

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6-(Dimethylamino)purine 25mg  | Purity Not Available

Selleck Chemicals

6-Dimethylaminopurine (N,N-Dimethyladenine) is a serine threonine protein kinase inhibitor. It inhibits the germinal vesicle breakdown and the meiotic maturation of oocytes.

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6-Aminopenicillanic acid 25mg  | Purity Not Available

Selleck Chemicals

6-Aminopenicillanic acid (6-APA) is the central component of penicillin β-lactam antibiotics which are generated by Penicillium. It is used as precursor for antibiotic compounds ampicillin and amoxicillin.

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6-Benzylaminopurine 100mg  | Purity Not Available

Selleck Chemicals

6-Benzylaminopurine is a first-generation synthetic cytokinin which could regulate the activities of the antioxidant defense system of plants.Its treatment elicits plant growth and development.

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6-Benzylaminopurine 500mg  | Purity Not Available

Selleck Chemicals

6-Benzylaminopurine is a first-generation synthetic cytokinin which could regulate the activities of the antioxidant defense system of plants.Its treatment elicits plant growth and development.

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6-Biopterin 5mg  | Purity Not Available

Selleck Chemicals

6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects.

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6-Biopterin 25mg  | Purity Not Available

Selleck Chemicals

6-Biopterin ( L-Biopterin, L-Erythro-Biopterin) is a natural product that has been considered as a growth factor for some insects.

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6-Bromo-2-hydroxy-3-methoxybenzaldehyde 25mg  | Purity Not Available

Selleck Chemicals

6-Bromo-2-hydroxy-3-methoxybenzaldehyde is a bromobenzaldehyde derivative that participates in the synthesis of (±)-norannuradhapurine. 6-Bromo-2-hydroxy-3-methoxybenzaldehyde is an IRE-1α inhibitor with an IC50 of 0.08 μM.

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6-Chloropurine 25mg  | Purity Not Available

Selleck Chemicals

6-Chloropurine is used in the preparation of 9-alkylpurines through alkylation with various substituted alkyl halides in dimethyl sulfoxide.

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6-Diazo-5-oxo-L-norleucine 2mg  | Purity Not Available

Selleck Chemicals

6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1  mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.

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6-Diazo-5-oxo-L-norleucine 5mg  | Purity Not Available

Selleck Chemicals

6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1  mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.

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6-Diazo-5-oxo-L-norleucine 25mg  | Purity Not Available

Selleck Chemicals

6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1  mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.

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6-Diazo-5-oxo-L-norleucine 100mg  | Purity Not Available

Selleck Chemicals

6-Diazo-5-oxo-L-norleucine (Diazooxonorleucine, L-6-Diazo-5-oxonorleucine, DON), an antibiotic isolated from Streptomyces, is a glutaminase antagonist with IC50 of ~1  mM for cKGA (kidney-type glutaminase). 6-Diazo-5-oxo-L-norleucine exhibits analgesic, antibacterial, antiviral and anticancer properties.

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6-Gingerol 5mg  | Purity Not Available

Selleck Chemicals

6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

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6-Gingerol 25mg  | Purity Not Available

Selleck Chemicals

6-Gingerol is the active constituent of fresh ginger known to exhibit a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

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6-Hydroxyflavone (6-HF) 25mg  | Purity Not Available

Selleck Chemicals

6-Hydroxyflavone, a naturally occurring flavonoid, binds to GABAA receptors with moderate affinity and acts as a partial agonist of GABAA receptors.

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6-Hydroxyindole 25mg  | Purity Not Available

Selleck Chemicals

6-Hydroxyindole (1H-indol-6-ol) is an endogenous potent and long-lasting OATP1B1 inhibitor with IC50 of ~10 μM.

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6-Maleimidohexanoic acid N-hydroxysuccinimide ester 50mg  | Purity Not Available

Selleck Chemicals

6-Maleimidohexanoic acid N-hydroxysuccinimide ester (EMCS) is a heterobifunctional cross-linking reagent. EMCS is used as a unique and useful reagent for preparation of hapten conjugate and enzyme immunoconjugates.

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6-Mercaptopurine (6-MP) Monohydrate 200mg  | Purity Not Available

Selleck Chemicals

6-Mercaptopurine (6-MP) Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

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6-Mercaptopurine (6-MP) Monohydrate 500mg  | Purity Not Available

Selleck Chemicals

6-Mercaptopurine (6-MP) Monohydrate is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.

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6-Methoxydihydrosanguinarine 1mg  | Purity Not Available

Selleck Chemicals

6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.

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6-Methoxydihydrosanguinarine 5mg  | Purity Not Available

Selleck Chemicals

6-Methoxydihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxydihydrosanguinarine shows strong cytotoxicity against MCF-7 and SF-268 cell lines with IC50 values of 0.61 μM and 0.54 μM, respectively.

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6-Methylcoumarin 25mg  | Purity Not Available

Selleck Chemicals

6-Methylcoumarin (Toncarine), a synthetic fragrance widely used in cosmetics, belongs to the class of organic compounds known as coumarins and derivatives.

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6-OAU 25mg  | Purity Not Available

Selleck Chemicals

6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay. 6-OAU (GTPL5846, 6-n-octylaminouracil) increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512 nM.

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6-OAU 5mg  | Purity Not Available

Selleck Chemicals

6-OAU (GTPL5846, 6-n-octylaminouracil) is a surrogate agonist of G protein-coupled receptor 84 (GPR84) that activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with EC50 of 105 nM in the PI assay. 6-OAU (GTPL5846, 6-n-octylaminouracil) increases [35S]GTPγS incorporated in Sf9 cell membranes expressing human GPR84-Gαi fusion protein with EC50 of 512 nM.

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6-OHDA (Oxidopamine hydrobromide) 25mg  | Purity Not Available

Selleck Chemicals

6-OHDA (Oxidopamine hydrobromide) is a neurotoxic synthetic organic compound that acts as an antagonist of the neurotransmitter dopamine with potential antineoplastic activity. Solutions are unstable and should be fresh-prepared.

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6-OHDA (Oxidopamine hydrobromide) 100mg  | Purity Not Available

Selleck Chemicals

6-OHDA (Oxidopamine hydrobromide) is a neurotoxic synthetic organic compound that acts as an antagonist of the neurotransmitter dopamine with potential antineoplastic activity. Solutions are unstable and should be fresh-prepared.

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6-Paradol 25mg  | Purity Not Available

Selleck Chemicals

6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities. Paradol is an inhibitor of cyclooxygenase (COX)-2.

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6-Paradol 1g  | Purity Not Available

Selleck Chemicals

6-Paradol is a minor constituent of ginger, mainly formed from 6-gingerol via 6-shogaol, and exhibits a variety of biological activities including anti-cancer, anti-inflammatory, and anti-oxidative activities. Paradol is an inhibitor of cyclooxygenase (COX)-2.

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6-Shogaol 1mg  | Purity Not Available

Selleck Chemicals

6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties.,

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6-Shogaol 5mg  | Purity Not Available

Selleck Chemicals

6-Shogaol, a naturally occuring product found in ginger, has anti-inflammatory and anticancer properties.,

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