Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteDeoxycorticosterone acetate (11-Deoxycorticosterone, DOC, Cortexone) is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
More Information Supplier PageDeoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignin from Anthriscus sylvestris with potent antimitotic, anti-inflammatory and antiviral activities.
More Information Supplier PageDeoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignin from Anthriscus sylvestris with potent antimitotic, anti-inflammatory and antiviral activities.
More Information Supplier PageDeoxyribonucleic acid, single-stranded from salmon testes, is a ready-to-use solution of a high-quality, sonicated, single-stranded template nonspecific DNA blocking agent that reduces background in nucleic acid hybridization.
More Information Supplier PageDeoxyribonucleic acid, single-stranded from salmon testes, is a ready-to-use solution of a high-quality, sonicated, single-stranded template nonspecific DNA blocking agent that reduces background in nucleic acid hybridization.
More Information Supplier PageDepatuxizumab (anti-ERBB1/ EGFR / HER1) is a humanized monoclonal antibody (MoAb) against the human epidermal growth factor receptor (EGFR) with antineoplastic activity. MW: 144.54 KD.
More Information Supplier PageDepatuxizumab (anti-ERBB1/ EGFR / HER1) is a humanized monoclonal antibody (MoAb) against the human epidermal growth factor receptor (EGFR) with antineoplastic activity. MW: 144.54 KD.
More Information Supplier PageDepatuxizumab (anti-ERBB1/ EGFR / HER1) is a humanized monoclonal antibody (MoAb) against the human epidermal growth factor receptor (EGFR) with antineoplastic activity. MW: 144.54 KD.
More Information Supplier PageDepatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).
More Information Supplier PageDepatuxizumab Mafodotin (Depatux-M, ABT-414) is an antibody-drug conjugate consisting of an EGFR IGg1 monoclonal antibody conjugated to the tubulin inhibitor monomethyl auristatin F via a stable maleimidocaproyl link. Depatuxizumab Mafodotin is used in the treatment of recurrent EGFR-amplified Glioblastoma (GBM).
More Information Supplier PageDepemokimab (Anti-IL-5) is a humanized monoclonal antibody (IgG1, kappa) directed against IL-5. Depemokimab can be used for research of asthma. MW : 145.8 KD.
More Information Supplier PageDepemokimab (Anti-IL-5) is a humanized monoclonal antibody (IgG1, kappa) directed against IL-5. Depemokimab can be used for research of asthma. MW : 145.8 KD.
More Information Supplier PageDepemokimab (Anti-IL-5) is a humanized monoclonal antibody (IgG1, kappa) directed against IL-5. Depemokimab can be used for research of asthma. MW : 145.8 KD.
More Information Supplier PageDequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.
More Information Supplier PageDequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.
More Information Supplier PageDeracoxib (SC-046) is a COX-2 inhibitor with >48-fold selectivity over COX-1. It also exhibits inhibitory activity against phosphodiesterase (Ki = 3.6 μM against human PDE4D3).
More Information Supplier PageDerazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
More Information Supplier PageDerazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
More Information Supplier PageDerazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
More Information Supplier PageDerazantinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with IC50 values of 1.8 nM for FGFR2, and 4.5 nM for FGFR1 and 3, showing lower potency for FGFR4 (IC50=34 nM). It also inhibits RET, DDR2, PDGFRβ, VEGFR and KIT.
More Information Supplier PageDerenofylline (SLV320) is a selective and potent adenosine A1 antagonist with Ki of 1 nM. Derenofylline shows selective for adenosine A1 over A2A, A2B, and A3 receptors with Ki of 398 nM, 3981 nM, and 200 nM, respectively.
More Information Supplier PageDerlotuximab is a recombinant human monoclonal antibody that targets DNA/histone (H1) complex. It is potentially used in the treatment of Glioblastoma multiforme (GBM), Cancers, brain, malignant glioma, Solid tumors. It is also used in certain immunoassay techniques. MW: 145.5 KD.
More Information Supplier PageDerlotuximab is a recombinant human monoclonal antibody that targets DNA/histone (H1) complex. It is potentially used in the treatment of Glioblastoma multiforme (GBM), Cancers, brain, malignant glioma, Solid tumors. It is also used in certain immunoassay techniques. MW: 145.5 KD.
More Information Supplier PageDerlotuximab is a recombinant human monoclonal antibody that targets DNA/histone (H1) complex. It is potentially used in the treatment of Glioblastoma multiforme (GBM), Cancers, brain, malignant glioma, Solid tumors. It is also used in certain immunoassay techniques. MW: 145.5 KD.
More Information Supplier PageDeruxtecan is an ADC drug-linker conjugate composed of the cleavable glycine-glycine-phenylalanine-glycine tetrapeptide-based linker, a self-immolative amino methylene spacer, and a novel topoisomerase 1 inhibitor payload that is a derivative of exatecan (DX-8951).
More Information Supplier PageDeschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
More Information Supplier PageDeschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
More Information Supplier PageDeschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
More Information Supplier PageDeschloroclozapine, a metabolite of Clozapine, is a highly potent muscarinic DREADDs (muscarinic Designer Receptors Exclusively Activated by Designer Drugs) agonist, and binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively.
More Information Supplier PageDesciclovir (DCV, 6-Deoxyacyclovir, BW A515U) is a prodrug of the antiherpetic agent acyclovir (ACV) that converted into ACV by xanthine oxidase in humans.
More Information Supplier PageDescolor Cinquefoil Herb Extract is extracted from Potentilla, which has anti-diabetic efficacy and may have beneficial effects on improving glucose uptake.
More Information Supplier PageDescurainiae Semen Lepidii Semen Extract is obtained from the dried ripe seeds of Descurainia sophia (L.) Webb ex Prantl or Lepidium apetalum Willd. (Brassicaceae), which has anti-inflammatory, analgesic, antipyretic, anticancer, and antioxidant properties, and is also used to treat functional constipation.
More Information Supplier PageDeserpidine (Harmonyl), an alkaloid isolated from the roots of Rauwolfia canescens, is a competitive angiotensin converting enzyme (ACE) inhibitor, also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.
More Information Supplier PageDesertliving Cistanche Herb Extract is extracted from Cistanche deserticola, which can regulate bone metabolism.
More Information Supplier PageDesidustat (ZYAN1, ZYAN1-1001), an antianaemic drug candidate, is an orally active hypoxia-inducible factor (HIF) prolyl hydroxylase (PHD) inhibitor (HIF-PHI) that stimulates erythropoiesis.
More Information Supplier PageDesipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.
More Information Supplier PageDesipramine hydrochloride (Desmethylimipramine, Norimipramine, EX-4355, G-35020, JB-8181, NSC-114901) is a dibenzazepine-derivative tricyclic antidepressant that acts as a selective norepinephrine reuptake inhibitor. It also shows weak serotonin reuptake inhibitory, α1-blocking, antihistamine, and anticholinergic effects.
More Information Supplier PageDeslanoside(Desacetyllanatoside C) is a cardenolide glycoside, has the effects of anti-arrhythmia and cardiotonic, also is used as an EC 3.6.3.9 (Na+/K+-transporting ATPase) inhibitor.
More Information Supplier PageDeslanoside(Desacetyllanatoside C) is a cardenolide glycoside, has the effects of anti-arrhythmia and cardiotonic, also is used as an EC 3.6.3.9 (Na+/K+-transporting ATPase) inhibitor.
More Information Supplier PageDeslanoside(Desacetyllanatoside C) is a cardenolide glycoside, has the effects of anti-arrhythmia and cardiotonic, also is used as an EC 3.6.3.9 (Na+/K+-transporting ATPase) inhibitor.
More Information Supplier PageDesloratadine (SCH-34117, NSC 675447) is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
More Information Supplier PageDesloratadine (SCH-34117, NSC 675447) is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
More Information Supplier PageDesloratadine (SCH-34117, NSC 675447) is a potent antagonist for human histamine H1 receptor with IC50 of 51 nM.
More Information Supplier PageDesmethyl Celecoxib (compound 3b), an analog of Celecoxib with the optimal yield of 75%, is a selective inhibitor of cyclooxygenase-2 (COX-2) with anti-inflammatory activities.
More Information Supplier PageDesMethyl Erlotinib (OSI-420) HCl is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM).
More Information Supplier PageDesmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor.
More Information Supplier PageDesmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).
More Information Supplier PageDesmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).
More Information Supplier PageDesmopressin is a synthetic octapeptide, and an analogue of human hormone arginine vasopressin with antidiuretic and coagulant activities. It is a selective agonist for the vasopressin V2 receptor (V2R).
More Information Supplier PageDesogestrel (Cerazette, Desogen, Desogestrelum, Org-2969) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.
More Information Supplier Page
