Selleck Chemicals supplies over 3,000 inhibitors used in the study of cell signaling pathways. We actively tracks the latest science so our customers can rely on us to be the leading supplier of the newest inhibitors.
Company WebsiteCosibelimab (Anti-B7-H1 / PD-L1 / CD274) is an immunoglobulin G1 (IgG1), human monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 144.64 KD.
More Information Supplier PageCosibelimab (Anti-B7-H1 / PD-L1 / CD274) is an immunoglobulin G1 (IgG1), human monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 144.64 KD.
More Information Supplier PageCosibelimab (Anti-B7-H1 / PD-L1 / CD274) is an immunoglobulin G1 (IgG1), human monoclonal antibody directed against the immunosuppressive ligand programmed cell death-1 ligand 1 (PD-L1; cluster of differentiation 274; CD274), with potential immune checkpoint inhibitory and antineoplastic activities. MW : 144.64 KD.
More Information Supplier PageCostunolide (NSC 106404), a natural sesquiterpene compound with multiple biological activities; inhibits FPTase with IC50 of 20 μM, also inhibits telomerase with IC50 of 65-90 μM.
More Information Supplier PageCostustoot Extract is extracted from the roots of costus, which has antibacterial properties and serves an inhibitory role in the regeneration of gut bacteria.
More Information Supplier PageCOTI-2 is an orally available third generation thiosemicarbazone and activator of mutant forms of the p53 protein, with potential antineoplastic activity.
More Information Supplier PageCOTI-2 is an orally available third generation thiosemicarbazone and activator of mutant forms of the p53 protein, with potential antineoplastic activity.
More Information Supplier PageCoumalic acid is a valuable platform compound which can be prepared from malic acid, can be used in the flavours, fragrances and cosmetics industries, as polymer components, and as pharmaceutical scaffolds displaying anti-bronchial and -malarial activity.
More Information Supplier PageCoumarin is a secondary phytochemical with hepatotoxic and carcinogenic properties.
More Information Supplier PageCoumarin 151 (7-Amino-4-(trifluoromethyl)coumarin) is a fluorescent tracer used for the detection of proteinases.
More Information Supplier PageCoumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.
More Information Supplier PageCoumarin-3-carboxylic acid is used as a detector for hydroxyl radicals (.OH) in aqueous solution.
More Information Supplier PageA unique collection of 843 covalent inhibitors or small molecule compounds with covalently reactive groups
More Information Supplier PageCp 43 (Compound 43, TAO Kinase inhibitor 1, TAOK inhibitor 43) is a ATP-competitive and selective TAO Kinase inhibitor with IC50s of 11 nM and 15 nM for TAOK1 and TAOK2, respectively.
More Information Supplier PageCp 43 (Compound 43, TAO Kinase inhibitor 1, TAOK inhibitor 43) is a ATP-competitive and selective TAO Kinase inhibitor with IC50s of 11 nM and 15 nM for TAOK1 and TAOK2, respectively.
More Information Supplier PageCp 43 (Compound 43, TAO Kinase inhibitor 1, TAOK inhibitor 43) is a ATP-competitive and selective TAO Kinase inhibitor with IC50s of 11 nM and 15 nM for TAOK1 and TAOK2, respectively.
More Information Supplier PageCP 640186 is an isozyme-nonselective ACC (Acetyl-CoA carboxylase) inhibitor with IC50 values of 53 and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2, respectively.
More Information Supplier PageCP-24879, an aniline derivative, is a potent, selective inhibitor of Delta(5)/Delta(6) desaturase.
More Information Supplier PageCP-24879, an aniline derivative, is a potent, selective inhibitor of Delta(5)/Delta(6) desaturase.
More Information Supplier PageCP-31398 Dihydrochloride stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.
More Information Supplier PageCP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells.
More Information Supplier PageCP-466722 is a potent and reversible ATM inhibitor, does not affect ATR and inhibits PI3K or PIKK family members in cells.
More Information Supplier PageCP-671305 is a potent, selective and orally active inhibitor of phosphodiesterase-4-D (PDE4-D) with IC50 of 3 nM.
More Information Supplier PageCP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity.
More Information Supplier PageCP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity.
More Information Supplier PageCP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity.
More Information Supplier PageCP-673451 is a selective inhibitor of PDGFRα/β with IC50 of 10 nM/1 nM in cell-free assays, exhibits >450-fold selectivity over other angiogenic receptors, has antiangiogenic and antitumor activity.
More Information Supplier PageCP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
More Information Supplier PageCP-724714 is a potent, selective inhibitor of HER2/ErbB2 with IC50 of 10 nM, >640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met etc in cell-free assays. Phase 2.
More Information Supplier PageCP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
More Information Supplier PageCP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
More Information Supplier PageCP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.
More Information Supplier PageCP2 is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively.
More Information Supplier PageCP2 is a cyclic peptide that inhibits the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively.
More Information Supplier PageCp2-SO4 is a phenylalanine derivative which reverses interleukin 4 induced 1 (IL4I1)-dependet inhibition of T-cell proliferation with Ki of 21.2 µM.
More Information Supplier PageCp2-SO4 is a phenylalanine derivative which reverses interleukin 4 induced 1 (IL4I1)-dependet inhibition of T-cell proliferation with Ki of 21.2 µM.
More Information Supplier PageCP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.
More Information Supplier PageCP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.
More Information Supplier PageCP21R7 is a potent and selective GSK-3β inhibitor that can potently activate canonical Wnt signalling.
More Information Supplier PageCPI-1189 (REN 1654, REN 1189) is the proapoptotic cytokine tumor necrosis factor (TNF) alpha inhibitor. CPI-1189 intracellularly inhibits the p38 mitogen-activated protein kinase phosphoactivation and shows neuroprotective effects.
More Information Supplier PageCPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
More Information Supplier PageCPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
More Information Supplier PageCPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
More Information Supplier PageCPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
More Information Supplier PageCPI-169 is a potent, and selective EZH2 inhibitor with IC50 of 0.24 nM, 0.51 nM, and 6.1 nM for EZH2 WT, EZH2 Y641N, and EZH1, respectively.
More Information Supplier PageCPI-203 is a potent BET bromodomain inhibitor with IC50 of 37 nM for BRD4.
More Information Supplier PageCPI-203 is a potent BET bromodomain inhibitor with IC50 of 37 nM for BRD4.
More Information Supplier PageCPI-203 is a potent BET bromodomain inhibitor with IC50 of 37 nM for BRD4.
More Information Supplier PageCPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.
More Information Supplier PageCPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases.
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