Safinamide is a dopamine reuptake inhibitor by being a highly selective inhibitor of MAO-B (IC50 = 98 nM. Additionally, this compound has a high affinity for Na+ channels (IC50 = 8 μM.

Saikosaponin A, a triterpenoid glycoside, induces apoptotic mechansims in human breast cancer cell lines. It also displays an inhibitory activity against allergic asthma. It mediates the inflammatory response by inhibiting the MAPK and NF-κB pathways in LPS-stimulated RAW 264.7 cells. It as antioxidants improve antioxidant status.

Saikosaponin C is extracted from the root of Bupleurum chinense DC. It efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation. It exhibits anti-HBV activity. It may have the potential for therapeutic angiogenesis but is not suitable for cancer therapy.

Saikosaponin D is extracted from the root of Bupleurum chinense DC. It protects against acetaminophen-induced hepatotoxicity by inhibiting NF-κB and STAT3 signaling. It possesses potent cytotoxicity against human hepatocellular carcinoma cells. It inhibits cell growth of human cancer cells by inducing apoptosis and blocking cell cycle progression in the G1 phase. It was found to […]

A short-acting beta-2 adrenergic agonist that is primarily used as a bronchodilator agent to treat ASTHMA.

Salcaprozate sodium (SNAC), an oral absorption promoter, and has the potential as a delivery agent for oral forms of heparin and insulin. Salcaprozate sodium could increase passive transcellular permeation across small intestinal epithelia based on increased lipophilicity arising from non-covalent macromolecule complexation.

Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea, has been reported to have a broad spectrum of pharmacological properties. Salidroside has whitening and anti-radiation effects, thus can be used in cosmetics material.

A selective ADRENERGIC BETA-2 RECEPTOR agonist that functions as a BRONCHODILATOR when administered by inhalation. It is used to manage the symptoms of ASTHMA and CHRONIC OBSTRUCTIVE PULMONARY DISEASE.

Calcitonin, Salmon is a calcium regulating hormone which exhibits hypocalcaemic and hypophosphatemic properties

Salvianolic acid A is extracted from the root of Salvia miltiorrhiza Bge. It has anti-oxidative capabilities. It can reverse paclitaxel resistance through suppressing transgelin 2 expression by mechanisms involving attenuation of PI3 K/Akt pathway activation and ABC transporter up-regulation. It has inhibitory effect on Cu2+ mediated human LDL oxidation through chelating Cu2+ and scavenging free […]

Salvianolic acid B is a natural product found in Salvia miltiorrhiza, Canna indica, and other organisms with data available.

Sanguinarine Chloride is also known as bloodwort redroot, red puccoon,and sometimes pauson. It has also been known as tetterwort,although that name is also used to refer to Chelidonium majus. Plants are variable in leaf and flower shape and have in the past been separated out as different subspecies due to these variable shapes. Currently most […]

Alpha-santonin is a santonin that is 3a,5,5a,9b-tetrahydronaphtho[1,2-b]furan-2,8(3H,4H)-dione substituted by methyl groups at positions 3, 5a and 9. It has a role as a plant metabolite. It is a botanical anti-fungal agent and a santonin.

Saponin is a surfactant that acts as a hemolytic agent.

It has a role as a coenzyme, a diagnostic agent, a human metabolite and a cofactor.

Sarolaner is an antiparasitic agent. It is used as veterinary drug.

Sarsasapogenin, that can be found in the rhizomes of Anemarrhena asphodeloides Bunge, exhibited antitumor activity by inducing apoptosis in vitro as determined by Hoechst staining analysis and double staining of Annexin V-FITC/PI. Most of the Sarsasapogenin derivatives displayed excellent selective cytotoxicity toward the cancer cell lines.

Used in its monohydrate form for the treatment of Type II diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor.

Used for the treatment of Type II diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. It contains a saxagliptin.

Schisandrol A has various therapeutic effects on a range of medical conditions such as anti-asthmatic, anti-cancer, and anti-inflammatory effects.

Sclareol is a labdane diterpenoid that is labd-14-ene substituted by hydroxy groups at positions 8 and 13. It has been isolated from Salvia sclarea. It has a role as an antimicrobial agent, an apoptosis inducer, a fragrance, an antifungal agent and a plant metabolite.

Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco. Sclareolide can increase and improve the sensory of food, so it has been widely used in the food industry.

Sclerotium Gum is a water soluble, nature-derived polysaccharide producedby fermentation of the filamentous fungus Sclerotium rolfsii. It is a highlyversatile ingredient, which improves the sensory characteristic of personalcare products. Scleroglucan has rheological properties, and unlike mostnatural and synthetic gums, has high thermal stability, is resistant tohydrolysis and retains skin moisture.

Scoparone is a member of the class of coumarins that is esculetin in which the two hydroxy groups at positions 6 and 7 are replaced by methoxy groups. It is a major constituent of the Chinese herbal medicine Yin Chen Hao, and exhibits a variety of pharmacological activities such as anti-inflammatory, anti-allergic, and anti-tumor activities. […]

It has a role as a muscarinic antagonist, an antiemetic, an adjuvant, a mydriatic agent, an antispasmodic drug, an anaesthesia adjuvant, an antidepressant and a metabolite.

Antimuscarinic quaternary ammonium derivative of scopolamine used to treat cramps in gastrointestinal, urinary, uterine, and biliary tracts, and to facilitate radiologic visualization of the gastrointestinal tract.

The agent is used to cause mydriasis, cycloplegia, to control the secretion of saliva and gastric acid, to slow gut motility, and prevent vomiting.

Scutellarin is the glycosyloxyflavone which is the 7-O-glucuronide of scutellarein. It has a role as an antineoplastic agent and a proteasome inhibitor. It is a glycosyloxyflavone, a glucosiduronic acid, a trihydroxyflavone and a monosaccharide derivative. It is functionally related to a scutellarein. It is a conjugate acid of a scutellarin(1-).

Sebacic acid is an alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. It has a role as a human metabolite and a plant metabolite. It is an alpha,omega-dicarboxylic acid and a dicarboxylic fatty acid. It is a conjugate acid of a sebacate(2-) and a sebacate. It derives from a hydride of a decane.

Secnidazole is a second-generation 5-nitroimidazole antimicrobial agent.

It finds its use in the manufacturing of pharma intermediates, lube additives and in paints & lacquer industries.

Selamectin is a topical parasiticide and antihelminthic used on dogs and cats to treat and prevent infections of heartworms, fleas, ear mites, sarcoptic mange, and certain types of ticks in dogs as well as prevent heartworms, fleas, ear mites, hookworms, and roundworms in cats. It also removes 2 types of lungworm in cats and one […]

It has a role as an orphan drug, a prostacyclin receptor agonist, a platelet aggregation inhibitor, a vasodilator agent and a prodrug.

Semaglutide is used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. It also works by slowing the movement of food through the stomach and may decrease appetite and cause weight loss.

Semaglutide is an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes. It reduces blood sugar via increasing the production of insulin. On Oct 18, 2017, Novo Nordisk received positive 16-0 vote from FDA Advisory Committee in favor of approval for Semaglutide.

Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.

(+)-sesamin is a lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity. It has a role as an antineoplastic agent, a neuroprotective agent and a plant metabolite. It is a lignan, a member of benzodioxoles and a furofuran.

Sesamol (CAS# 533-31-3) is a natural component of sesame oil with antioxidant activity. Sesamol has potential protective effects against free radicals as well as some antifungal activity. Sesamol can also be used as an intermediate in the preparation of antidepressants such as Paroxetine (P205750).

A polymeric amine that binds phosphate and is used to treat HYPERPHOSPHATEMIA in patients with kidney disease.

Sevelamer Hcl is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.

Sevofurane is a noncompetitive inhibitor of the 5-HT3 receptor and can be used as an inhaled anesthetic with low solubility.

Intermediate for Oseltamivir Phosphate

Naturally occurring (-)-form is a major biosynthetic precursor of phenylalanine, tyrosine, and tryptophan and hence of the majority of plant alkaloids. Shikimic acid is also involved in the biosynthesis of lignin, flavonpids and other important aromatic compounds.

Silibinin has been used to study its effect on gene expression levels of various proteins involved in chromatin regulations of prostate cancer.

Transparent to gray, odorless powder. Irritating to the skin and eyes on contact. Inhalation will cause irritation in the respiratory tract. [Note: Amorphous silica is the non-crystalline form of SiO2.]