Docusate Sodium
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Doxacurium chloride is a potent non-depolarizing neuromuscular blocking agent. Doxacurium chloride binds to cholinergic receptors to antagonize acetylcholine, resulting in a block of neuromuscular transmission. Doxacurium chloride can be used for the research of neurological diseases.
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Dolutegravir
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Dolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI). The effect of this drug has no homology in human host cells, which gives it excellent tolerability and minimal toxicity.
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Donepezil
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Donepezil is a racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer’s disease where it is used to increase cortical acetylcholine. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a nootropic agent and an EC 3.1.1.8 (cholinesterase) inhibitor.
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5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone is one of Donepezil impurities. Donepezil, a highly specific reversible acetylcholinesterase (AChE) inhibitor, is used to treat moderate to severe Alzheimer’s disease.
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Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil, which is a centrally acting reversible acetyl cholinesterase inhibitor for the treatment of moderate to severe Alzheimer’s disease.
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An indan and piperidine derivative that acts as a selective and reversible inhibitor of ACETYLCHOLINESTERASE. Donepezil is highly selective for the central nervous system and is used in the management of mild to moderate DEMENTIA in ALZHEIMER DISEASE.
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DOPC
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DOPC is a phospholipid containing unsaturated long-chain oleic acid, and it is commonly used alone or in combination with other components for the generation of micelles, liposomes, lipid vesicles, and artificial membranes.
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DOPE
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Doramectin
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Doramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle.
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DOTA
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Gadobutrol Impurity 9 is an impurity of Gadobutrol, which is a nonionic, paramagnetic contrast agent developed for tissue contrast enhancement in magnetic resonance imaging (MRI).
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DOTA
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Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals.
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Tetraxetan is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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DOTAP
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DOTAP is a potent cationic lipid used as a liposomal transfection reagent. DOTAP can be used for in vivo and in vitro protein and accounting delivery.
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Doxazosin
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An antihypertensive agent, it is used in the treatment of high blood pressure. It has a role as an antihypertensive agent, an alpha-adrenergic antagonist, an antineoplastic agent, a vasodilator agent and an antihyperplasia drug.
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Doxazosin mesylate selectively antagonizes alpha-1-adrenergic receptors in smooth muscle of the bladder neck and prostate, thereby relaxing the smooth muscle and decreasing the obstruction and urethral resistance seen with benign prostate hyperplasia (BPH). This may improve BPH symptoms. This agent also blocks alpha-1-adrenergic receptors in peripheral vascular smooth muscle, which leads to vasodilatation and a […]
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Doxercalciferol
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It is used to treat secondary hyperparathyroidism, a condition in which the body produces excess parathyroid hormone (PTH; a natural substance needed to control the amount of calcium in the blood) in certain people with chronic kidney disease. It has a role as a provitamin, a bone density conservation agent and a prohormone.
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Doxofylline
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Doxorubicin hydrochloride (liposomal) is an antineoplastic prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain types of cancer, including ovarian cancer, multiple myeloma, and AIDS-related Kaposi sarcoma.
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Doxycycline Hyclate is the hyclate salt form of doxycycline, a synthetic, broad-spectrum tetracycline antibiotic exhibiting antimicrobial activity. Doxycycline hyclate binds reversibly to the 30S ribosomal subunit, possibly to the 50S ribosomal subunit as well, thereby blocking the binding of aminoacyl-tRNA to the mRNA-ribosome complex. This leads to an inhibition of protein synthesis. In addition, this […]
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Drospirenone
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Drospirenone is a steroid lactone and a 3-oxo-Delta(4) steroid. It has a role as a contraceptive drug, an aldosterone antagonist and a progestin.
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Drostanolone enanthate is an anabolic steroid that belongs to the class of androgenic hormones. It is a synthetic derivative of dihydrotestosterone (DHT) and has potent anticancer activity against prostate carcinoma cells. Drostanolone enanthate inhibits the growth of cancer cells by binding to the androgen receptor, which is located in the cytoplasm. This causes a conformational […]
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Drostanolone propionate is a synthetic anabolic steroid that has been shown to inhibit the growth of renal cell cancer cells. It is used as a component of isotonic solutions for sample preparation in mouse tumor studies. Drostanolone propionate also has a role in the treatment of radiation-induced bowel disease and may be useful in the […]
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DSPA
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DSPC
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DSPC is a phospholipid containing saturated long-chain stearic acid, which is mainly used in the preparation of liposomes for drug delivery system research.
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DSPE-PEG
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DSPE-PEG is a polyethylene glycol/phosphatidylethanolamine conjugate that can be used primarily in drug delivery systems.
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5′-O-DMT-thymidine 3′-CE phosphoramidite is an immensely critical compound employed in the solid-phase synthesis of oligonucleotides, the building blocks of DNA. The chemical is a phosphoramidite derivative of thymidine, which dutifully incorporates into the growing strand of DNA during synthesis, and crucially, in turn, dictates the eventual structure of the resultant chemical entity.
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dTTP
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Duloxetine
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(S)-3-(dimethylamino)-1-(thiophen-2-yl)propan-1-ol is an impurity of Duloxetine, an antidepressant medication used to treat major depressive disorder.
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dUMP. Na2
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dUMP. Na2 is an indispensable precursor within the nucleotide research and development pathway, assuming a pivotal role in facilitating the comprehension of intricate DNA replication and repair mechanisms.
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Dutasteride
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Dutasteride is used for the treatment of symptomatic benign prostatic hyperplasia in men with an enlarged prostate gland. It has a role as an EC 1.3.1.22 [3-oxo-5alpha-steroid 4-dehydrogenase (NADP(+))] inhibitor and an antihyperplasia drug.
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dUTP
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dUTP is a deoxynucleoside triphosphate (dNTP) that acts as a substrate for several enzymes. It can be used in PCR and qPCR.
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DUTP is a deoxyuridine phosphate having a triphosphate group at the 5′-position. It has a role as a human metabolite, an Escherichia coli metabolite, a mouse metabolite and an Arabidopsis thaliana metabolite. It is a pyrimidine 2′-deoxyribonucleoside 5′-triphosphate and a deoxyuridine phosphate. It is a conjugate acid of a dUTP(3-).
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Dyclonine Hydrochloride is the hydrochloride salt of Dyclonine, an unclassified compound with local anesthetic effect.
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