Deferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.

Deflazacort, also known as Emflaza, is a corticosteroid prodrug used as an agent to manage Duchenne Muscular Dystrophy (DMD).

Degarelix is used for the treatment of advanced prostate cancer. Degarelix is a synthetic peptide derivative drug which binds to gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland and blocks interaction with GnRH.

Degarelix Acetate is the acetate form of a long-acting, synthetic peptide with gonadotrophin-releasing hormone (GnRH) antagonistic properties. Degarelix targets and blocks GnRH receptors located on the surfaces of gonadotroph cells in the anterior pituitary, thereby reducing secretion of luteinizing hormone (LH) by pituitary gonadotroph cells and so decreasing testosterone production by interstitial (Leydig) cells in […]

It has a role as a metabolite, a trypanocidal drug, an antineoplastic agent, a cyclooxygenase 2 inhibitor, an antimycobacterial drug and an apoptosis inducer. It is a sesquiterpene lactone, a guaiane sesquiterpenoid, an organic heterotricyclic compound and a gamma-lactone.

Delafloxacin meglumine is a fluoroquinolone that can be used to treat acute bacterial skin and skin structure infections (ABSSSI) in adult patients. Studies indicated that it has excellent tolerance and low toxicity to liver and kidney.

An impurity in the synthesis of Fluorometholone, a glucocorticoid used for the treatment of eye conditions caused by inflammation.

A tetracycline antibiotic, it is used (mainly as the hydrochloride) for the treatment of Lyme disease, acne and bronchitis, as well as for hyponatraemia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective. It has a role as an antibacterial drug and an aquaretic. […]

Dendrobine, that can be found in the herb of Dendrobium nobile Lindl, produces moderate hyperglycemia, diminishes cardiac activity in large doses, lowers the blood pressure. Dendrobine on the electrical activity and on amino acid-induced depolarizations of primary afferent terminals were tested on the frog isolated spinal cord.

DeoxyArbutin is a reversible tyrosinase inhibitor, inhibiting tyrosinase activity with IC50 of 50 nM.

It has a role as a human blood serum metabolite.

Deoxycorticosterone acetate is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as a precursor to aldosterone.

DEPBT is a peptide coupling reagent used in peptide synthesis. It shows remarkable resistance to racemization.

Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations.

Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.

Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body.

Antidiuretic

A synthetic analog of the pituitary hormone, ARGININE VASOPRESSIN. Its action is mediated by the VASOPRESSIN receptor V2. It has prolonged antidiuretic activity, but little pressor effects. It also modulates levels of circulating FACTOR VIII and VON WILLEBRAND FACTOR

Desogestrel is a 17beta-hydroxy steroid and a terminal acetylenic compound. It has a role as a contraceptive drug, a progestin and a synthetic oral contraceptive.

A nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.

Desvenlafaxine succinate hydrate is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI).

The acetate-protect form of Dexamethasone which is a glucocorticoid and could be used as an anti-inflammatory agent. It can be used for various inflammations, allergic diseases, bovine ketoneemia, sheep pregnancy toxemia, and can also be used for the simultaneous delivery of female animals.

a glucocorticoid receptor agonist

Dexibuprofen is used as an antipyretic analgesic.

Non-steroid anti-inflammatory

Dexrazoxane, also referred to as ADR-529, is an organo-metallic compound widely employed in scientific research. It inhibits Topo II (DNA topoisomerase II) without inducing DNA strand breaks. Dexrazoxane is a (+)enantiomer of razoxane (sc-253425). Dexrazoxane also decreases formation of reactive oxygen species (ROS) and activates the PI3K/Akt survival pathway. Furthermore, dexrazoxane is thought to inhibit […]

A group of glucose polymers made by certain bacteria. Dextrans are used therapeutically as plasma volume expanders and anticoagulants. They are also commonly used in biological experimentation and in industry for a wide variety of purposes.

Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors […]

A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.

D-glutamic acid is an optically active form of glutamic acid having D-configuration. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a D-alpha-amino acid and a glutamic acid. It is a conjugate acid of a D-glutamate(1-). It is an enantiomer of a L-glutamic acid.

2′-Deoxyguanosine-5′-monophosphate, a nucleotide molecule and a key player in DNA synthesis, holds immense potential in the development of antiviral drugs as well as in treating various cancers. This biochemical marker is additionally crucial in detecting and measuring DNA damage, a necessary step in studying the complex mechanisms of DNA replication and repair.

dGTP is a stable nucleotide used in the in vivo synthesis of DNA.

dGTP is a stable nucleotide used in the in vivo synthesis of DNA.

Docosahexaenoic acid is found in fish oils in nature. It is alsocommercially manufactured from microalgae; Crypthecodiniumcohnii and Schizochytrium.

Di-1-adamantylphosphine is a useful research chemical.

Tert-butoxycarbonyl anhydride is an acyclic carboxylic anhydride. It is functionally related to a dicarbonic acid.

A useful reagent for the efficient phosphorylative conversion of alcohols into their corresponding dibenzylphosphorotriesters. It is applied as a phosphitylating agent in water-soluble phosphate prodrugs of 1-propargyl-8-styrylxanthine derivatives, a2a-selective adenosine receptor antagonists.

Di-tert-butyl phosphite is used as a solvent, as an antioxidant, and as an intermediate.

Di-tert-butyl(methyl)phosphonium tetrafluoroborate can be used in the preparation of a precursor for nantenine analogs bearing a C4 phenyl substituent, which shows an affinity for 5-HT2B receptor.

Phosphonium salts are ligand precursors for the palladium-catalyzed amination, and Suzuki coupling.