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Botulinum Toxin A reduces muscle tension by blocking the release of acetylcholine from nerve endings. Clinically, Botulinum Toxin A is used to treat blepharospasm, dystonia and other diseases.
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Br-U
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Br-U is a building block for oligonucleotide union and holds immense potential in therapies for diseases like cancer and viral infections. Notably, owing to its distinctive chemical features, it can tinker with the structure and function of nucleic acids, facilitating precise treatment, and improved delivery of medications.
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BrettPhos Pd G3
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BrettPhos Pd G3 can be used for C-N coupling reactions between monosubstituted ureas and 1,2 dihalogenated aromatic systems to generate benzo imidazolones.
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Brexpiprazole
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Brimonidine
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Brinzolamide
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Bromomethyl cyclopentane is an alkyl cyclopentyl core analog, which can be used as an organic chemical synthesis intermediate.
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Bruceantin
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Bruceantin is a triterpene quassinoid antineoplastic antibiotic isolated from the plant Brucea antidysenterica. Bruceantin inhibits the peptidyl transferase elongation reaction, resulting in decreased protein and DNA synthesis. Bruceantin also has antiamoebic and antimalarial activity. (NCI04)
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Bruceine A
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Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical […]
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Bumetanide
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Bumetanide is a Loop Diuretic. The physiologic effect of bumetanide is by means of Increased Diuresis at Loop of Henle.
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Bupivacaine
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Bupivacaine HCL
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Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
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Bupivacaine Hydrochloride is a long-acting, amide-type local anesthetic. Bupivicaine reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation.
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Bupropion HCl
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An anxiolytic agent and serotonin receptor agonist belonging to the azaspirodecanedione class of compounds. Its structure is unrelated to those of the BENZODIAZAPINES, but it has an efficacy comparable to DIAZEPAM.
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Butenafine hydrochloride is the hydrochloride salt of butenafine. An inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, it is used for treatment of dermatological fungal infections. It has a role as an EC 1.14.13.132 (squalene monooxygenase) inhibitor and an antifungal drug.
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Butyl Acrylate
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Ufenamate is a topical analgesic.Target:Ufenamate is an anthranilic acid-based anti-inflammatory drug developed for skin diseases, such as acute and chronic eczema, contact dermatitis, diaper dermatitis, miliaria and atopic dermatitis.
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BHA, commonly known as butyl hydroxyanisole, is a mixture of two isomers of 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.It has excellent solubility in oils and fats and excellent “carry in” capability in baked and fried foods. BHA provides excellent stability for a variety of foods, fats, oils and food packaging materials.
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Butyl levulinate (CAS# 2052-15-5) is used in preparation and application of magnetic nano-solid acid catalyst iron oxide-polydopamine-sulfonic acid.
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CataCXium A is an electron-rich phosphine ligand used for palladium catalyzed cross-coupling reactions like Heck and Suzuki coupling reactions.
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5′-O-DMT-N6-Benzoyl-2′-deoxyadenosine 3′-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology.
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5′-O-DMT-N4-Benzoyl-2′-deoxycytidine 3′-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2′-deoxycytidine in modified DNA oligonucleotides.
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Bz-rA
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N6-Benzoyladenosine is a purine nucleoside that is synthesized from uridine and has a high resistance to phosphorylation. It is found in the mitochondrial matrix of rat hepatocytes and can be used as a specific agent for the treatment of symptoms related to Parkinson’s disease. N6-Benzoyladenosine inhibits protein synthesis by inhibiting the catalytic subunit of guanine […]
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N-Benzoyl-5′-O-(4,4-Dimethoxytrityl)-2′-O-[(tert-butyl)dimethylsilyl]adenosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used to incorporate nucleoside A into the synthesis of oligonucleotides.
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Acts as a microtubule inhibitor, binds tubulin and promotes microtubule assembly and simultaneously inhibits disassembly. It has a role as an antineoplastic agent and a microtubule-stabilising agent. It is functionally related to a 10-deacetylbaccatin III.
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Cabazitaxel
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Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity.
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Cabozantinib
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A multi-tyrosine kinase inhibitor, used (as its malate salt) for the treatment of progressive, metastatic, medullary thyroid cancer. It has a role as a tyrosine kinase inhibitor and an antineoplastic agent.
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A multi-tyrosine kinase inhibitor, used for the treatment of progressive, metastatic, medullary thyroid cancer. It has a role as a tyrosine kinase inhibitor, an antineoplastic agent and a prodrug.
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Caffeic acid
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It exists in cis and trans forms; the latter is the more common. It has a role as a plant metabolite, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an EC 2.5.1.18 (glutathione transferase) inhibitor, an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor, an antioxidant and an EC 3.5.1.98 (histone deacetylase) inhibitor. It is a hydroxycinnamic acid and a […]
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It has a role as an antineoplastic agent, an anti-inflammatory agent, an immunomodulator, a metabolite, an antioxidant, a neuroprotective agent, an antiviral agent and an antibacterial agent.
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It has a role as a central nervous system stimulant, an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor, an adenosine receptor antagonist, an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor, a ryanodine receptor agonist, a fungal metabolite, an adenosine A2A receptor antagonist, a psychotropic drug, a diuretic, a food additive, an adjuvant, a plant metabolite, an […]
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Calcifediol
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The major circulating metabolite of vitamin D3 (cholecalciferol). It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of rickets and osteomalacia, both in azotemic and non-azotemic patients. Calcifediol also has mineralizing properties.
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Calcifediol
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25-Hydroxyvitamin D3, also called Calcifediol, is a major metabolite of vitamin D formed by hydroxylation in the liver. Of all the circulating forms of Vitamin D3, 25-Hydroxyvitamin D3 is the principal form. It plays a critical role in calcium metabolism, bone health, and immune function. It has also been found to have anti-inflammatory, anti-cancer, and […]
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Calcipotriol
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It is used (as its hydrate) in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients. It has a role as a drug allergen and an antipsoriatic.
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Calcipotriol hydrate is a hydrate that is the monohydrate form of calcipotriol. It is used in combination with betamethasone dipropionate, a corticosteroid, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic.
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Calcitriol
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It has a role as a bone density conservation agent, an antipsoriatic, an immunomodulator, an antineoplastic agent, a calcium channel modulator, a nutraceutical, a calcium channel agonist, a metabolite, a hormone, a human metabolite and a mouse metabolite.
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Calcium acetate
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Calcium Acetate is a calcium salt of acetic acid. Calcium is a mineral essential for many cellular functions including nerve impulse transmission, muscle contraction, cardiac function, bone formation, and capillary and cell membrane permeability. Calcium acetate is administered orally to prevent or treat calcium deficiency and to treat hyperphosphatemia due to its phosphate-binding properties.
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