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6-Methylnicotinic acid is an intermediate of the drug etoricoxib (a non- steroidal anti-inflammatory drug for the treatment of arthritis and osteoarthritis). It is also used as organic intermediates.
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6-VIC phosphoramidite is an asymmetrical xanthene dye widely used to prepare fluorescence-labeled oligonucleotides and design qPCR probes, such as TaqMan, Molecular Beacon, and Scorpion. Its spectral characteristics are similar to HEX and JOE, emitting fluorescence in the green-yellow range. 6-VIC phosphoramidite can efficiently label oligonucleotides at their 5′-end using standard or automated synthesis protocols. Protecting […]
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7-ACA
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7beta-aminocephalosporanic acid is the alpha,beta-unsaturated monocarboxylic acid that is the active nucleus for the synthesis of cephalosporins and intermediates. It is functionally related to a cephalosporanic acid. It is a tautomer of a 7beta-aminocephalosporanic acid zwitterion.
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7-AMCA
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7-Azaspiro[3.5]nonane-2,7-dicarboxylic acid, 7-(1,1-dimethylethyl) ester is used as a reagent in the preparation of mineralocorticoid receptor agonists.
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7-Bromopyrrolo[1,2-f][1,2,4]triazin-4-amine is used in preparation of N-Heterocyclic compounds for pharmaceutical use including as anticancer agents and PRMT5 inhibitors.
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7-Deaza-2′,3′-dideoxy-7-iodoadenosine is an exceedingly potent antiviral compound, extensively employed to study specific viral afflictions, predominantly triggered by RNA viruses. By selectively zeroing in on the viral polymerase and curtailing the compoundion of viral RNA, this pharmaceutical compound obstructs viral replication flawlessly.
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7-Deaza-2′,3′-dideoxy-7-iodoguanosine, a compound of significant importance in the biomedical sector, possesses remarkable capacities to selectively combat various ailments, predominantly viral infections, through hindering viral replication. Its multifaceted antiviral properties pave the way for potential breakthroughs in viral infection treatment. Augmenting therapeutic outcomes in preclinical investigations, this substance exhibits immense promise when administered in conjunction with […]
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It is a derivative of 7-Iodo-7-deazadenine and is designed to be incorporated into DNA by using Vent(exo-) polymerase primers extension.
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7-Deaza-2′-deoxy-7-iodoguanosine is a potent antiviral compound used in biomedicine. It exhibits antiviral activity against Herpes Simplex Virus (HSV) and Varicella-Zoster Virus (VZV). This nucleoside analogue acts by inhibiting viral DNA synthesis, making it effective in the treatment of HSV and VZV infections. It is commonly used in research and drug development related to antiviral therapies.
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7-Deaza-7-lodo-2′-Deoxyguanosine is a modified oligonucleotide containing 7-Deazaadenine that can be used in sequencing reactions.
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7-Deaza-7-lodo-2′-Deoxyguanosine is a deoxyguanosine derivative that can be used in DNA synthesis and gene sequencing reactions.
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7-Deaza-7-Propargylamino-3′-Azidomethyl-dGTP is an analogue of dGTP and is widely used in DNA sequencing reactions.
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7-ethyl-10-hydroxycamptothecin (SN 38) is a liposomal formulation of the active metabolite of Irinotecan [DB00762], a chemotherapeutic pro-drug approved for the treatment of advanced colorectal cancer. SN 38 has been used in trials studying the treatment of Cancer, Advanced Solid Tumors, Small Cell Lung Cancer, Metastatic Colorectal Cancer, and Triple Negative Breast Cancer, among others.
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The main reasons for the superior antitumor activity of 7-Ethylcamptothecin compared with CPT are as follows: (a) 7-Ethylcamptothecin had a stronger growth-inhibiting activity against tumor cells, and (b) 7-Ethylcamptothecin remained in the intestinal tract for a longer time and in higher amounts when administered in vivo. 7-Ethyl Camptothecin is a natural compound found in the […]
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4-methylumbelliferone is a hydroxycoumarin that is umbelliferone substituted by a methyl group at position 4. It has a role as an antineoplastic agent and a hyaluronic acid synthesis inhibitor. It is functionally related to an umbelliferone.
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As a widely used intermediate, 7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine can be used in the synthesis of Ridecivir.
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7-MAC
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7-Methoxy-2-tetralone can be used in the synthesis of 2-bromo-3,4-dihydro-7-methoxy-1-naphthaldehyde and 2-substituted octahydrobenzo[f]quinolines.
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7-TDA
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7-Amino-3-[(5-methyl-1,3,4-thiadiazol-2-ylthio)methyl]-3-cephem-4-carboxylic Acid is a substrate used in the assessment of immobilized PGA orientation and in the synthesis of beta lactam antibiotics.
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