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4-Chloro-6,7-dimethoxyquinoline can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.
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4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is an important pharmaceutical intermediate. Also, 4-Chloro-7H-pyrrolo[2,3-d] pyrimidine is the intermediate of the bulk drug, Tofatinib, which was widely used in treatment of adult patients with moderate to severe rheumatoid arthritis with inadequate or intolerant methotrexate response.
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4-Chlorobenzophenone, is a building block used in various chemical synthesis. It can be used for the preparation of a variety of functionalized Coumarin derivatives.
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4-Chloropyrimidine hydrochloride is used in the synthesis of pharmaceuticals and agrochemicals, and has antiviral and antitumor activity.
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4-Fluorobenzoyl chloride (CAS# 403-43-0) is used in the synthesis of tryphostins which act as inhibitors of EGF receptor and Erb82/neu tyrosine kinases. Also used in the synthesis of 1,2,4-triazole-3-thiones as antidepressant agents.
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4-HO-DET
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4-Hydroxy-N,N-diethyltryptamine (4-HO-DET) is a hallucinogenic tryptamine of moderate duration; a psychedelic compound.
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4-Hydroxycoumarin is a plant derived antioxidant, protecting against lipid peroxidation, as well as a potential inhibitor of HIV-1 Integrase. 4-Hydroxycoumarin is an important class of biologically active drugs which is widely used as anticoagulants.
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4-Hydroxyindole
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4-Hydroxyindole is a Pindolol (P468000) impurity, which is a mixed adrenergic blocker and serotonin 5HT1A-receptor antagonist.
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4-Hydroxyphenylacetic acid is a compound present in olive oil. An important fine chemical intermediate with broad prospects for application development.
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4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. It is used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.
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4-Iodopyrazole
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4-Iodopyrazole (CAS# 3469-69-0) is used in the synthesis of (pyrazolyl)oxobenzocycloheptapyridinyl acetamides that act as inhibitors of c-Met.
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4-Methyl-3-nitrobenzoic acid can be used in the synthesis of one-dimensional (1D) lanthanide coordination complexes.
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4-Nitrobenzophenone (CAS# 1144-74-7) is used in the quantitative structural activity relationship analysis of benzophenone derivatives as antimalarial agents.
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