2′-Deoxyadenosine Monohydrate is used in the synthesis of 5′-modified 2′-deoxyadenosine analogues as anti-hepatitis C virus agents.

2′-deoxyadenosine is a purine 2′-deoxyribonucleoside having adenine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2′-deoxy-D-ribonucleoside and a purine 2′-deoxyribonucleoside.

2′-Deoxyguanosine HCl is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose.

2′-deoxycytidine is a pyrimidine 2′-deoxyribonucleoside having cytosine as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a cytosine.

2′-deoxyguanosine is a purine 2′-deoxyribonucleoside having guanine as the nucleobase. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2′-deoxy-D-ribonucleoside and a purine 2′-deoxyribonucleoside. It is functionally related to a guanosine.

2′-deoxyinosine is a purine 2′-deoxyribonucleoside that is inosine in which the hydroxy group at position 2′ is replaced by a hydrogen. It has a role as a Saccharomyces cerevisiae metabolite, a human metabolite, a plant metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a purines 2′-deoxy-D-ribonucleoside and a purine 2′-deoxyribonucleoside. It is […]

2′-deoxyuridine is a pyrimidine 2′-deoxyribonucleoside having uracil as the nucleobase. It has a role as a human metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a uracil.

2′-DeoxyXanthosine (dX) is a naturally occurring nucleoside that may be derived from oxidative deamination of 2′-deoxyGuanosine (dG). dX has a similar bonding pattern to thymidine and it may base pair with dA, with such purine-purine interactions causing duplex distortion. dX also featured in attempts to extend the genetic alphabet with a new base pair of […]

N4-Acetyl-2′-deoxy-2′-fluorocytidine is an efficacious antiviral compound, finding extensive application within the biomedical sector for studying viral infections such as hepatitis B, hepatitis C and HIV by impeding viral replication.

5′-O-DMT-N4-Acetyl-2′-fluoro-2′-deoxy-cytidine 3′-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides.

N6-Benzoyl-2′-deoxy-2′-fluoroadenosine is a useful research chemical.

N6-Benzoyl-2′-deoxy-5′-O-DMT-2′-fluoroadenosine 3′-CE phosphoramidite can be used to incorporate 2-fluoro modified nucleotides into oligonucleotides, improving metabolic stability.

2′-Deoxy-2′-fluoroadenosine (CAS# 64183-27-3) is a useful compound for the preparation of AB680, which is a potent and selective inhibitor of CD73.

It is used for RNA synthesis and nucleoside modification.

2′-Deoxy-2′-fluoro-N2-isobutyrylguanosine, a remarkable and influential compound, is extensively utilized in the realm of biomedical research. Its widespread application lies in investigating the impeding effect it manifests on viral RNA synthesis across diverse viral infections.

5′-O-DMT-2′-fluoro-N2-isobutyryl-2′-Deoxy-guanosine 3′-CE phosphoramidite is a novel nucleoside analog for the incorporation of 2-fluoro-modified ribose-G nucleobases within oligonucleotides.

5′-O-(4,4′-Dimethoxytrityl)-2′-deoxy-2′-fluorouridine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a useful research chemical.

2′-Fluoroacetophenone is used as starting reagent in the synthesis of ascididemin. It is used to produce 1-(2-piperidin-1-yl-phenyl)-ethanone by reaction with piperidine.

DMT-locMeC(bz) Phosphoramidite belongs to the group of LNA phosphoramidite. It is known as DMT-5-Me-locCytidine(N4-Benzoyl)- ß-Cyanoethylphosphoramidite.

LNA-A(Bz) amidite can be used for synthesis of ASOs (antisense oligonucleotides).

DMTr-LNA-G(iBu)-3′-CED-phosphoramidite is a phosphoramidite used in the biomedical industry for the synthesis of modified nucleic acids. It contains DMTr-protected LNA-G(iBu)-3′-CED, which enables efficient and stable incorporation of modified bases during DNA/RNA synthesis.

DMTr-LNA-5MeU-3-CED-phosphoramidite is vital for Locked Nucleic Acid (LNA) oligonucleotide synthesis, which features a ribonucleoside connected by a methylene unit between 2′-oxygen and 4′-carbon atoms, mirroring DNA polymerization in structure and process.

2′-O-MOE-5MeU-3′-phosphoramidite can be used in the synthetic preparation of nucleic acids.

2′-O-MOE-A(Bz)-3′-phosphoramidite is used diagnostically in the screening of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) oligonucleotidic modulators.

N-Benzoyl-5′-O-(4,4-Dimethoxytrityl)-2′-O-[(tert-butyl)dimethylsilyl]adenosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used to incorporate nucleoside A into the synthesis of oligonucleotides.

Ac-rC Phosphoramidite is a commonly used protected 2-OTBDMS phosphoramidite for incorporating cytidine nucleotides into synthetic oligonucleotides.

5′-O-DMT-2′-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3′-CE phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used for incorporating ribo-G into synthetic oligonucleotides.

5′-DMT-2’O-TBDMS-rU Phosphoramidite is a classic 2-OTBDMS phosphoramidite used to incorporate U into synthetic oligonucleotides.

N-Acetyl-5′-O-(4,4-dimethoxytrityl)-2′-O-methylcytidine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is used to incorporate 2-O-methyl modified nucleotides into oligonucleotides. It is a novel nucleoside analogue drug that inhibits tumor growth and activates RNA polymerase II promoter transcription.

N2-Acetyl-5′-O-DMT-2′-O-methylguanosine 3′-CE phosphoramidite is an organic compound that has been modified to be an anticancer agent. It has been shown to have antiviral and antiparasitic activities.

N-Benzoyl-5′-O-(4,4′-dimethoxytrityl)-2′-O-methyladenosine-3′-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite is a nucleotide used in the synthesis of native-like crosslinked duplex RNA.

2′-OMe-ibu-G Phosphoramidite is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.

5′-O-DMT-2′-O-methyluridine 3′-CE phosphoramidite is a phosphoramidite reagent used to introduce 2-O-methyl modified U nucleotide into oligonucleotides.

2′,3′-dideoxyadenosine is a purine 2′,3′-dideoxyribonucleoside in which the nucleobase component is specified as adenine. It has a role as an EC 4.6.1.1 (adenylate cyclase) inhibitor and an EC 3.5.4.4 (adenosine deaminase) inhibitor. It is a purine 2′,3′-dideoxyribonucleoside and a member of adenosines.

Zalcitabine is a pyrimidine 2′,3′-dideoxyribonucleoside compound having cytosine as the nucleobase. It has a role as an antiviral drug, an antimetabolite and a HIV-1 reverse transcriptase inhibitor.

2′,3′-Dideoxyguanosine is a nucleoside analog. It executes an impeding stratagem against replication by skillfully substituting naturally occurring nucleosides within the viral DNA, hence obstructing its ambulatory growth.

An antiviral drug, it is used as a medication to treat HIV/AIDS. It has a role as an antimetabolite, a HIV-1 reverse transcriptase inhibitor, an antiviral drug, an EC 2.4.2.1 (purine-nucleoside phosphorylase) inhibitor and a geroprotector.

2′,3′-Dideoxyuridine is a nucleoside analog used in biomedical research. It impedes viral replication by incorporating into viral DNA and inducing chain termination. It is used for studying HIV and other retroviral infections.

2′,3′-dideoxyadenosine is a purine 2′,3′-dideoxyribonucleoside in which the nucleobase component is specified as adenine. It has a role as an EC 4.6.1.1 (adenylate cyclase) inhibitor and an EC 3.5.4.4 (adenosine deaminase) inhibitor. It is a purine 2′,3′-dideoxyribonucleoside and a member of adenosines.

Zalcitabine is a pyrimidine 2′,3′-dideoxyribonucleoside compound having cytosine as the nucleobase. It has a role as an antiviral drug, an antimetabolite and a HIV-1 reverse transcriptase inhibitor.

A metabolite of Capecitabine.

20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

20-Deoxyingenol is a diterpene derivative of Ingenol, isolated from the seeds of Euphorbia lathyris L., which has anti-tumor activity when used topically for the treatment of actinic keratosis.

20-hydroxyecdysone is an ecdysteroid that is ecdysone substituted by a hydroxy group at position 20. It has a role as a plant metabolite and an animal metabolite. It is a 20-hydroxy steroid, an ecdysteroid, a 14alpha-hydroxy steroid, a 3beta-sterol, a 2beta-hydroxy steroid, a 22-hydroxy steroid, a 25-hydroxy steroid and a phytoecdysteroid. It is functionally related […]