Mimicking the action of progesterone, hydroxyprogesterone caporate binds to and activates nuclear progesterone receptors in the reproductive system and causes the ligand-receptor complex to be translocated to the nucleus where it binds to and promotes expression of target genes. Due to the negative feedback mechanism seen with progesterone, this agent also blocks luteinizing hormone (LH) […]

17a-Hydroxyprogesterone is an antiestrogen compound.

17alpha-hydroxyprogesterone is a 17alpha-hydroxy steroid that is the 17alpha-hydroxy derivative of progesterone. It has a role as a metabolite, a progestin, a human metabolite and a mouse metabolite. It is a 17alpha-hydroxy steroid, a 17alpha-hydroxy-C21-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a progesterone.

Medroxyprogesterone Acetate EP Impurity H is an impurity of Medroxyprogesterone Acetate, which is a progestin-type hormonal drug used in menopausal hormone therapy and progestogen-only birth control.

An intermediate in the synthesis of Finasteride. Finasteride is a 4-azasteroid analog of testosterone that competitively blocks type II 5α-reductase activity with 100-fold greater affinity than for the type I enzyme.

Methyl salicylate is a benzoate ester that is the methyl ester of salicylic acid. It has a role as a flavouring agent, a metabolite and an insect attractant. It is a benzoate ester, a member of salicylates and a methyl ester. It is functionally related to a salicylic acid.

Glycyrrhetinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30. It has a role as an immunomodulator and a plant metabolite. It is a pentacyclic triterpenoid, a cyclic terpene ketone and a hydroxy monocarboxylic acid. […]

19-Norandrostenedione refers to two steroid isomers that were once marketed as dietary supplements and mainly used by body builders. After 2005, 19-Norandrostenedione was regulated in the United States as a schedule III controlled substance, as well as banned from use in competitive sports by the World Anti-Doping Agency. In the body 19-norandrostenedione is rapidly metabolized […]

[1,2,4]Triazole-1-carboxamidine is an intermediate used in the synthesis of peramivir (P285500), a neuraminidase inhibitor developed as an antiviral agent for the treatment of influenza.

1H-Imidazole-4-carbaldehyde is a 4-formyl derivative of imidazole used in the preparation of C17,20-lyase inhibitor for the treatment of androgen-dependent prostate cancer. It is also used in the synthesis of other biologically active compounds such as antimalarial drugs, fabrication of colorimetric chemosensor.

1H-Imidazole-4-carbonitrile is a vital pharmaceutical intermediate, and can act as a reagent in the structure-based optimization of a potent class of arylamide FMS inhibitors.

1H-Pyrrol-1-amine can be used in organic synthesis and pharmaceutical intermediates.

An impurity of Ticagrelor which is a reversible P2Y12 receptor antagonist and is unique in its greater and more rapid and consistent, yet reversible, inhibition of the ADP receptor.

2-(1-Cyclohexenyl)ethylamine (CAS# 3399-73-3) is an intermediate used to synthesize (cyclohexenyl)ethyl (5-halopyridyl) thioureas as inhibitors of multidrug-resistant human immunodeficiency virus-1. It is also used to prepare dextromethorphan (D299455, HBr monohydrate salt), a morphinan.

2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]phenyl-2-propanol is a montelukast impurity.

2-(2-(4-fluorophenyl)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl) acetate is used as an intermediate in the atorvastatin series.

2-(2-Bromoethyl)-1,3-dioxolane is used as a pharmaceutical intermediate, dioxolanes, acetals, ketals, building blocks, chemical synthesis, organic building blocks and oxygen compounds. 1,1-(Ethylenedioxy)-3-bromopropane is used in the synthesis of EGFR inhibitors. Also used in the synthesis of orally active agents of cancer and cell proliferation with quinoline substructures.

2-(2-Chlorophenyl)-2-nitrocyclohexanone is a useful research chemical.

2-(2-Cyanethyl)cyclohexanone may be used in the synthesis of 4-keto-nona-1,9-dioic acid by reacting with hydrogen peroxide.

Dihydroavenanthramide D is a natural alkaloid that exerts antihistamine, antioxidant, anti-irritation, anti-inflammatory, and anti-erythema effects. It has a good effect on relieving itching, irritation, and redness of sensitive skin. It is suitable for anti-inflammation and anti-sensitivity, soothing repair, antibacterial, oil control acne, enhanced skin immunity, and other products. Dihydroavenanthramide D can effectively inhibit pruritus, contact […]

2-(4-Bromo-2-chlorophenoxy)-N-(4-(N-(4,6-dimethylpyriMidin-2-yl)sulfamoyl)phenylcarbamothioyl)acetamide is a selective inhibitor of Cdc42, and effectively inhibits EGF-stimulated Cdc42 activity including microspike formation in 3T3 fibroblasts and neuronal branching in primary neonatal cortical neurons.

2-(4-Bromophenyl)naphthalene is used in the preparation of α-Phosphonosulfonate compounds which inhibit the enzyme squalene and thereby inhibit cholesterol biosynthesis.

2-(4-hydroxyphenyl)ethanol is a phenol substituted at position 4 by a 2-hydroxyethyl group. It has a role as an anti-arrhythmia drug, an antioxidant, a cardiovascular drug, a protective agent, a fungal metabolite, a geroprotector and a plant metabolite. It is functionally related to a 2-phenylethanol.

2-(4-Nitrophenyl)propionic acid is a reagent used in the preparation of α-Methylated analogs of triiodothyroalkanoic acids which have interactions with hepatic thyroid receptors.

One of the impurities of Sulpiride that is effective in studies of dopamine D2 receptor function as well as antipsychotic studies.

2-Chloromethyl-3,4-dimethoxypyridine-[d7] Hydrochloride, exhibits special chemical structure, might be a compound useful in organic synthesis of some deuterium labelled inhibitor.

Rockpahos is commonly used as a catalyst in organic reactions along with a palladium compound catalyst.

Buchwald Phosphine Ligands for chemical Synthesis

2-(Di-tert-butylphosphino)-1,1”-binaphthyl is a reagent used as ligand in palladium-catalyzed C-O, C-N, and C-C bond forming reactions.