Tadalafil is used for the treatment of erectile dysfunction, whichis a phosphodiesterase 5 inhibitor.

Tenofovir alafenamide is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic hepatitis B virus infection (HBV) in adults and children 12 years of age and older who meet certain requirements, as determined by a health care provider.

Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis. It has a role as a central nervous system drug.

A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha.

Taltirelin is a thyrotropin-releasing hormone receptor (TRH-R) superagonist with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release).

Antineoplastic, an estrogen-competitive antagonist, is a non-steroidal anti-estrogen drug that competes with estrogen (estradiol) in the body and binds to the estrogen receptor of breast cancer cells, thereby inhibiting the action of estrogen on cancer cells.

It is an anxiolytic drug used in the treatment of anxiety disorders. It has a role as an anxiolytic drug and an antidepressant.

Tangeretin is a pentamethoxyflavone flavone with methoxy groups at positions 4′, 5, 6 , 7 and 8. It has a role as an antineoplastic agent and a plant metabolite.

Tangeretin is a methoxyflavone compound found in citrus fruits that demonstrates antiproliferative and antioxidant effects. Tangeretin is described to block cell cycle progression at G1 in MDA-MB-435, MCF-7, and HT-29 cell lines. In human T47D cells, Tangeretin was demonstrated to inhibit ERK1/2 (extracellular-signal-regulated kinases 1/2) phosphorylation. Antioxidant activity is as reported with Tangeretin, and it […]

Tannic acid is a polyphenolic compound. It is a type of the commercially available tannins. It acts as a weak acid. Tannic acid is found in the nutgalls formed by insects on twigs of certain oak trees (Quercus infectoria and other Quercus species). It is removed and used as medicine. In the old days it […]

Tanshinone I isolated from the roots of Salvia miltiorrhiza. It can protect against peroxynitrite-induced DNA damage, and hydroxyl radical formation and cytotoxicity, might have implications for Tanshinone I-mediated neuroprotection.

Sodium tanshinone IIA sulfonate for injection can protect neuron cell against damage. It may be used to treatment brain ischemia disease in clinical

Tanshinone IIA, under the IUPAC name 1,6,6-trimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione, one of the original anthracyclines isolated from Salvia miltiorrhiza, inhibits β-amyloid aggregation and protects PC12 cells from β-amyloid-induced apoptosis. Tanshinone IIA is a natural compound which has anti-oxidative properties, can be used in cosmetics material.

neuropathic pain therapy

Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness.

Taurine is a non-selective endogenous glycine receptor agonist, which is widely used in the pharmaceutical industry and food industry.

It has a role as a human metabolite, an anti-inflammatory agent, a neuroprotective agent, an apoptosis inhibitor, a cardioprotective agent and a bone density conservation agent.

(+)-taxifolin is a taxifolin that has (2R,3R)-configuration. It has a role as a metabolite. It is a conjugate acid of a (+)-taxifolin(1-). It is an enantiomer of a (-)-taxifolin.

Taxifolin exhibits important anti-tyrosinase activity. Taxifolin exhibits significant inhibitory activity against collagenase with an IC50 value of 193.3 μM.

It is used for nucleoside modification and nucleic acid synthesis.

5′-O-DMT-2′-O-TBDMS-N-Bz-Adenosine is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.

5’-O-DMT-2’-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.

TBTU is an ideal coupling reagent for solid-phase peptide synthesis.

tBuBrettPhos Pd G3 is used as a precatalyst for the N-arylation of amino acid esters with aryl trifluoromethyl sulfonate under mild reaction conditions.

A 18-carbon fatty acid side chain of semaglutide. The affinity of the semaglutide side chain for albumin was enhanced 5-6 times. Semaglutide is a glucagon-like peptide-1 (GLP-1) analog with significant hypoglycemic efficacy.

Semaglutide intermediate is an intermediate of Semaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes.

An intermediate in the synthesis of Semaglutide, an agonist of glucagon-like peptide-1 (GLP-1) receptor that is developed to treat type 2 diabetes.

Effective ligand for the Pd-catalyzed arylation of pyrazoles, indazoles and amino heterocycles

tBuXPhos Pd G3 is an organometollic compound, which is an excellent reagent for Buchwaldd-Hartwig cross-coupling reaction, with lower catalyst loading, shorter reaction time, effective formation of active catalytic species and precise control of the ligand-to-palladium ratio.

Triclocarban is a member of the class of phenylureas that is urea substituted by a 4-chlorophenyl group and a 3,4-dichlorophenyl group at positions 1 and 3 respectively. It has a role as a disinfectant, an antiseptic drug, an antimicrobial agent, an environmental contaminant and a xenobiotic. It is a dichlorobenzene, a member of monochlorobenzenes and […]

Tebipenem side chain is a key intermediate in the synthesis of penem drugs and has important applications in the pharmaceutical industry.

Tecovirimat is an antiviral prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of smallpox in adults and children. (Smallpox is a disease caused by the variola virus, a member of the orthopoxvirus group of viruses. Since 1980, smallpox has been considered eradicated worldwide.) Although tecovirimat is only approved for […]

Tedizolid Phosphate is the phosphate salt form of tedizolid, an antibacterial agent of the oxazolidinone class, that is used for the treatment of acute bacterial skin and skin structure infections caused by certain Gram-positive microorganisms.

Teduglutide is a dipeptidyl peptidase IV resistant glucagon-like peptide 2 (GLP-2) analogue. Teduglutide is associated with trophic effects on gut mucosa. Teduglutide can be used for the research of short bowel syndrome (SBS) and Crohn’s disease (CD).

Treatment of intestinal diseases characterized by chemical orsurgical damage of the intestinal epithelium such as ShortBowel Syndrome (SBS) or damage to the intestinalepithelium due to disease (glucagon-like peptide-2 (GLP-2) analog).

Tegafur is a congener of the antimetabolite fluorouracil with antineoplastic activity. Tegafur is a prodrug that is gradually converted to fluorouracil in the liver by the cytochrome P-450 enzyme.

Lipoglycopeptide antibiotic from Actinoplanes teichomyceticus active against gram-positive bacteria. It consists of five major components each with a different fatty acid moiety.

Used for treatment of adults with complicated skin and skin structure infections caused by bacteria. It has a role as an antibacterial drug and an antimicrobial agent. It contains a telavancin.

Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.

Teneligliptin hydrobromide is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor. It competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro.

Tenofovir disoproxil is an organic phosphonate that is the disoproxil ester of tenofovir. A prodrug for tenofovir, an HIV-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of HIV infection. It has a role as a prodrug, a HIV-1 reverse transcriptase inhibitor and an antiviral […]

Tenofovir Disoproxil Fumarate is an acyclic phosphonate nucleotide analog and selective HIV-1 RT inhibitor