MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Isosorbide mononitrate 10mM/1mL  | ≥98%

MedChem Express

Isosorbide mononitrate(Isosorbide-5-mononitrate) is a nitrate-class compound used for angina pectoris; acts by dilating the blood vessels so as to reduce the blood pressure.

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Isospaglumic acid 50mg  | ≥98%

MedChem Express

Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain. In Vitro: Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the […]

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Isospaglumic acid 10mg  | ≥98%

MedChem Express

Isospaglumic acid is a neuropeptide found in millimolar concentrations in brain. In Vitro: Isospaglumic acid (N-Acetylaspartylglutamate; NAAG) is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the […]

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Isosteviol 5mg  | ≥98%

MedChem Express

Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a noncaloric sugar substitute in Japan and Brazil. Target: Isosteviol dose-dependently relaxed the vasopressin (10-8 M)-induced vasoconstriction in isolated aortic rings with or without endothelium. However, in the presence of potassium chloride (3×10-2 M), the vasodilator effect of isosteviol […]

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Isosteviol 10mg  | ≥98%

MedChem Express

Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a noncaloric sugar substitute in Japan and Brazil. Target: Isosteviol dose-dependently relaxed the vasopressin (10-8 M)-induced vasoconstriction in isolated aortic rings with or without endothelium. However, in the presence of potassium chloride (3×10-2 M), the vasodilator effect of isosteviol […]

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Isosteviol 10mM/1mL  | ≥98%

MedChem Express

Isosteviol is a derivative of stevioside, a constituent of Stevia rebaudiana, which is commonly used as a noncaloric sugar substitute in Japan and Brazil. Target: Isosteviol dose-dependently relaxed the vasopressin (10-8 M)-induced vasoconstriction in isolated aortic rings with or without endothelium. However, in the presence of potassium chloride (3×10-2 M), the vasodilator effect of isosteviol […]

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Isotanshinone I 5mg  | ≥98%

MedChem Express

Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE, with IC50s of 1.13, 0.432 μM for α-glucosidase and AGE, respectively. IC50 & Target: IC50: 1.13μM (α-glucosidase), 0.432 μM (AGE)[1].

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Isotanshinone IIA 5mg  | ≥98%

MedChem Express

Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. IC50 & Target: IC50: 11.4 μM (PTP1B)[1].

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Isotretinoin 10 mM * 1 mL  | Purity Not Available

MedChem Express

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne.

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Isotretinoin 100mg  | ≥98%

MedChem Express

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more. Target: RAR/RXR Isotretinoin has been the most effective and long-lasting drug for the treatment of severe acne for more than 30 years […]

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Isotretinoin 500mg  | ≥98%

MedChem Express

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more. Target: RAR/RXR Isotretinoin has been the most effective and long-lasting drug for the treatment of severe acne for more than 30 years […]

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Isotretinoin 10mM/1mL  | ≥98%

MedChem Express

Isotretinoin(13-cis-Retinoic acid) is a medication used for the treatment of severe acne. It was first developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more. Target: RAR/RXR Isotretinoin has been the most effective and long-lasting drug for the treatment of severe acne for more than 30 years […]

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Isovaleramide 100 mg  | Purity Not Available

MedChem Express

Isovaleramide is an active principle on central nervous system from Valeriana pavonii, as an anticonvulsant.

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Isovaleramide 100mg  | ≥98%

MedChem Express

Isovaleramide is an active principle on central nervous system from Valeriana pavonii, as an anticonvulsant. Target: in vitro: Isovaleramide (300 μM) exhibits a 42% of inhibition of the binding of 3H-FNZ to its sites. in vivo: Isovaleramide at 100 mg/Kg, p.o, evidences a 90% index protection against the maximal electroshock seizure in mice (MES).

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Isovanillin 1g  | ≥98%

MedChem Express

Isovanillin is an aldehyde oxidase inhibitor[1]. Antispasmodic activities[2]. Antidiarrheal activities[3]. IC50 & Target: Aldehyde oxidase[1] In Vitro: Isovanillin is not a substrate for aldehyde oxidase and therefore it is metabolized to isovanillic acid predominantly by aldehyde dehydrogenase[1]. Isovanillin is relaxant of ileum contractions induced by 5-HT (IC50=356±50μM) [2]. In Vivo: Isovanillin (2 mg/kg & 5 […]

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Isovanillin 10mM/1mL  | ≥98%

MedChem Express

Isovanillin is an aldehyde oxidase inhibitor[1]. Antispasmodic activities[2]. Antidiarrheal activities[3]. IC50 & Target: Aldehyde oxidase[1] In Vitro: Isovanillin is not a substrate for aldehyde oxidase and therefore it is metabolized to isovanillic acid predominantly by aldehyde dehydrogenase[1]. Isovanillin is relaxant of ileum contractions induced by 5-HT (IC50=356±50μM) [2]. In Vivo: Isovanillin (2 mg/kg & 5 […]

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Isovanillin 10 mM * 1 mL  | 99.89%

MedChem Express

Isovanillin is an aldehyde oxidase inhibitor[1]. Antispasmodic activities[2]. Antidiarrheal activities[3].

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Isovitexin 10mg  | ≥98%

MedChem Express

Isovitexin is a flavonoid isolated from rice hulls of Oryza sativa, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. IC50 & Target: JNK1/2, NF-κB[1] In Vitro: Isovitexin protects against LPS-induced oxidative damage by suppressing intracellular ROS generation, and also attenuates the effect of H2O2 on cell […]

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Isovitexin 25mg  | ≥98%

MedChem Express

Isovitexin is a flavonoid isolated from rice hulls of Oryza sativa, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. IC50 & Target: JNK1/2, NF-κB[1] In Vitro: Isovitexin protects against LPS-induced oxidative damage by suppressing intracellular ROS generation, and also attenuates the effect of H2O2 on cell […]

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Isovitexin 5mg  | ≥98%

MedChem Express

Isovitexin is a flavonoid isolated from rice hulls of Oryza sativa, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. IC50 & Target: JNK1/2, NF-κB[1] In Vitro: Isovitexin protects against LPS-induced oxidative damage by suppressing intracellular ROS generation, and also attenuates the effect of H2O2 on cell […]

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Isovitexin 10mM/1mL  | ≥98%

MedChem Express

Isovitexin is a flavonoid isolated from rice hulls of Oryza sativa, possesses anti-inflammatory and anti-oxidant activities; Isovitexin acts like a JNK1/2 inhibitor and inhibits the activation of NF-κB. IC50 & Target: JNK1/2, NF-κB[1] In Vitro: Isovitexin protects against LPS-induced oxidative damage by suppressing intracellular ROS generation, and also attenuates the effect of H2O2 on cell […]

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Ispinesib 10mM/1mL  | ≥98%

MedChem Express

Ispinesib is a specific inhibitor of KSP, with a Ki app of 1.7 nM. IC50 & Target: Ki app: 1.7 nM (KSP)[1] In Vitro: Ispinesib is a potent, highly specific inhibitor of KSP, with a Ki app of 1.7 nM[1]. Ispinesib (150 nM) inhibits BT-474 and MDA-MB-468 cell lines, with GI50s of 45 and 19 […]

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Ispinesib 10mg  | ≥98%

MedChem Express

Ispinesib is a specific inhibitor of KSP, with a Ki app of 1.7 nM. IC50 & Target: Ki app: 1.7 nM (KSP)[1] In Vitro: Ispinesib is a potent, highly specific inhibitor of KSP, with a Ki app of 1.7 nM[1]. Ispinesib (150 nM) inhibits BT-474 and MDA-MB-468 cell lines, with GI50s of 45 and 19 […]

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Ispinesib 50mg  | ≥98%

MedChem Express

Ispinesib is a specific inhibitor of KSP, with a Ki app of 1.7 nM. IC50 & Target: Ki app: 1.7 nM (KSP)[1] In Vitro: Ispinesib is a potent, highly specific inhibitor of KSP, with a Ki app of 1.7 nM[1]. Ispinesib (150 nM) inhibits BT-474 and MDA-MB-468 cell lines, with GI50s of 45 and 19 […]

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Isradipine 10mM/1mL  | ≥98%

MedChem Express

Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM. Target: Calcium Channel Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack[1]. Isradipine belongs to the dihydropyridine (DHP) class […]

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Isradipine 10mg  | ≥98%

MedChem Express

Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM. Target: Calcium Channel Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack[1]. Isradipine belongs to the dihydropyridine (DHP) class […]

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Isradipine 50mg  | ≥98%

MedChem Express

Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM. Target: Calcium Channel Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack[1]. Isradipine belongs to the dihydropyridine (DHP) class […]

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Isradipine 100mg  | ≥98%

MedChem Express

Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM. Target: Calcium Channel Isradipine(Dynacirc) is a calcium channel blocker with an IC50 of 34±8 μM.It is usually prescribed for the treatment of high blood pressure in order to reduce the risk of stroke and heart attack[1]. Isradipine belongs to the dihydropyridine (DHP) class […]

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ISRIB (trans-isomer) 10mM/1mL  | ≥98%

MedChem Express

ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. IC50 & Target: IC50: 5 nM (PERK)[1] In Vitro: Trans-ISRIB is 100-fold more potent (IC50=5 nM) than cis-ISRIB (IC50= 600 nM), indicating that the compound’s interaction with its cellular target is stereospecific. ISRIB reduces the viability of cells subjected to PERK-activation […]

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ISRIB (trans-isomer) 10mg  | ≥98%

MedChem Express

ISRIB (trans-isomer) is a potent inhibitor of PERK with an IC50 of 5 nM. IC50 & Target: IC50: 5 nM (PERK)[1] In Vitro: Trans-ISRIB is 100-fold more potent (IC50=5 nM) than cis-ISRIB (IC50= 600 nM), indicating that the compound’s interaction with its cellular target is stereospecific. ISRIB reduces the viability of cells subjected to PERK-activation […]

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