MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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KSK94 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

KSK94 is a high-affinity histamine H3 receptor antagonist, with Kis of 7.9, 2958, 75.2 nM for H3 receptor, sigma-1, sigma-2 receptor respectively. KSK94 can be used for research of nociceptive and neuropathic pain[1].

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KT-531 | MedChemExpress (MCE) 5 mg  | ≥98.00%

MedChem Express

KT-531 is a potent and selective inhibitor of HDAC6 with an IC50 of 8.5 nM. KT-531 exhibits strong inhibition against SUP-T11 cells with an IC50 of 0.42 μM. KT-531 can be used in study hematological cancers[1].

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KTX-582 intermediate-1 | MedChemExpress (MCE) 5 mg  | 98.61%

MedChem Express

KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-1 | MedChemExpress (MCE) 10 mg  | 98.61%

MedChem Express

KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-1 | MedChemExpress (MCE) 25 mg  | 98.61%

MedChem Express

KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-1 | MedChemExpress (MCE) 50 mg  | 98.61%

MedChem Express

KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-1 | MedChemExpress (MCE) 100 mg  | 98.61%

MedChem Express

KTX-582 intermediate-1 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-2 | MedChemExpress (MCE) 5 mg  | ≥98.00%

MedChem Express

KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-2 | MedChemExpress (MCE) 10 mg  | ≥98.00%

MedChem Express

KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-2 | MedChemExpress (MCE) 25 mg  | ≥98.00%

MedChem Express

KTX-582 intermediate-2 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-582 intermediate-3 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

KTX-582 intermediate-3 is an intermediate in the synthesis of KTX-582 (HY-148274) and can be used for ADC preparation. KTX-582 is an IRAK4 degrader and inducer of apoptosis with DC50 of 4 nM and 5 nM for IRAK4 and Ikaros, respectively[1].

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KTX-Sp2 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

KTX-Sp2 is a potassium channel toxin. KTX-Sp2 effectively blocks three types of exogenous voltage-gated potassium channels: Kv1.1, Kv1.2 and Kv1.3. Ktx-Sp2 inhibits endogenous Kv1.3 and suppresses Ca2+ signaling in Jurkat T cells. Ktx-Sp2 inhibits IL-2 secretion from activated Jurkat T cells[1].

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Ku70 Antibody (YA319) | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

Ku70 Antibody (YA319) is a non-conjugated and Rabbit origined monoclonal antibody about 70 kDa, targeting to Ku70. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

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Ku70 Antibody (YA319) | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

Ku70 Antibody (YA319) is a non-conjugated and Rabbit origined monoclonal antibody about 70 kDa, targeting to Ku70. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

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Ku70 Antibody (YA319) | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

Ku70 Antibody (YA319) is a non-conjugated and Rabbit origined monoclonal antibody about 70 kDa, targeting to Ku70. It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human.

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Ku80 Antibody (YA714) | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

Ku80 Antibody (YA714) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to Ku80 (8H1). It can be used for WB,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Monkey.

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Ku80 Antibody (YA714) | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

Ku80 Antibody (YA714) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to Ku80 (8H1). It can be used for WB,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Monkey.

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Ku80 Antibody (YA714) | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

Ku80 Antibody (YA714) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to Ku80 (8H1). It can be used for WB,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Monkey.

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Ku80 Antibody | MedChemExpress (MCE) 10 uL  | ≥98.00%

MedChem Express

Ku80 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Ku80. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human.

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Ku80 Antibody | MedChemExpress (MCE) 50 uL  | ≥98.00%

MedChem Express

Ku80 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Ku80. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human.

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Ku80 Antibody | MedChemExpress (MCE) 100 uL  | ≥98.00%

MedChem Express

Ku80 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 83 kDa, targeting to Ku80. It can be used for WB,ICC/IF,IHC-P,IP assays with tag free, in the background of Human.

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Kuguaglycoside C | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Kuguaglycoside C is a triterpene glycoside that can be isolated from the leaves of Momordica charantia. Kuguaglycoside C induces caspase‐independent DNA cleavage and cell death of neuroblastoma cells. Kuguaglycoside C also significantly increases the expression and cleavage of apoptosis-inducing factor (AIF)[1].

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Kurtoxin | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Kurtoxin is a selective Cav3 (T-type) voltage-gated Ca2+ channel gating inhibitor with a Kd of 15 nM for Cav3.1 (α1G T-type) Ca2+ channel. Kurtoxin can interact with high affinity with native neuronal high-threshold L-type, N-type, and P-type Ca2+ channels in central and peripheral neurons. Kurtoxin also shows cross-reactivity with voltage-gated Na+ channel[1].

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KuWal151 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

KuWal151 is a CLK1, CLK2 and CLK4 inhibitor with a high selectivity margin towards DYRK kinases. KuWal151 has potent antiproliferative activity in an array of cultured cancer cell lines[1].

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Kuwanon U | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

Kuwanon U is a potent cholinesterase inhibitor with IC50s of 19.69, 10.11 µM and Kis of 6.48, 9.59 µM for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), respectively. Kuwanon U has the potential for the research of Alzheimer’s disease (AD)[1].

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KV1.3-IN-1 | MedChemExpress (MCE) 1 mg  | ≥98.00%

MedChem Express

KV1.3-IN-1 (Compound trans-18) is a KV1.3 channel inhibitor (IC50: 230 nM and 26.12 nM in Ltk? cells and PHA-activated T-lymphocytes respectively). KV1.3-IN-1 impairs intracellular Ca2+ signaling. KV1.3-IN-1 inhibits T-cell activation, proliferation, and colony formation[1].

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KV2 channel inhibitor-1 | MedChemExpress (MCE) 5 mg  | 98.46%

MedChem Express

KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels[1].

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KV2 channel inhibitor-1 | MedChemExpress (MCE) 10 mg  | 98.46%

MedChem Express

KV2 channel inhibitor-1 is a selective KV2 channel inhibitor with IC50s of 0.2 μM and 0.41 μM for KV2.1 and KV2.2, respectively. KV2 channel inhibitor-1 possesses good selectivity over KV1.2 (IC50>10 μM). KV2 channel inhibitor-1 is >10-fold selective over NaV channels and other KV channels and displays weak activity on CaV channels[1].

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