MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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15(R)-Prostaglandin D2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

15(R)-Prostaglandin D2 is a potential prostatic hormone DP(2) receptor (Prostaglandin Receptor) agonist with anti-inflammatory activity. 15(R)-Prostaglandin D2 increases actin polymerization in human eosinophils and increases cAMP levels in platelets[1].

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15(R)-PTA2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

15(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase[1].

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16-HETE | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

16-HETE is arachidonic acid metabolite through subterminal hydroxylation by cytochrome P-450. 16-HETE exhibits vasodilatory and PMN inhibitory effects and serves as biomarker for early stages of non-alcoholic fatty liver disease[1][2][3].

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16,16-Dimethyl prostaglandin A1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

16,16-Dimethyl prostaglandin A1 (di-Me-PGA1) is a prostaglandin analog that can inhibit DNA synthesis in Lewis lung carcinoma and B 16 amelanotic melanoma cells. 16,16-Dimethyl prostaglandin A1 also inhibits viral replication in both HSV and HIV-1 infection systems[1][2].

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16,17-Bis(decyloxy)violanthrone | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

16,17-Bis(decyloxy)violanthrone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely […]

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16:0 Coenzyme A triammonium | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

16:0 Coenzyme A triammonium is palmitoyl-CoA, which can serve as a reaction substrate to transfer the palmitoyl group to the free thiol group of the target protein through palmitoylation catalyzed by protein acyl transferases (PATs)[1].

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16(S)-Iloprost | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

16(S)-Iloprost is a stereoisomer of Iloprost. 16(S)-Iloprost inhibited platelet aggregation with IC50 value of 3.5 nM, and balanced binding with platelet membrane receptors Kd value of 13.4 nM[1].

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17-HDHA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27+ CD38+ antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells[1][2].

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17-HETE | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17-HETE is arachidonic acid metabolite through cytochrome P-450 pathways, which consists of 17R-HETE and 17S-HETE enantiomers. 17-HETE serves as allosteric activator of the cytochrome P450 1B1 and inhibitor of ATPase, induces cardic hypertrophy[1][2].

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17-Phenyl-18,19,20-trinor-PGD2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17-Phenyl-18,19,20-trinor-PGD2 (17-Phenyl-PGD2) is an analogue of prostaglandin D2 (PGD2; HY-101988). 17-Phenyl-18,19,20-trinor-PGD2 is a potent inhibitor of platelet aggregation caused by aenosine diphosphate (ADP), with the IC50 of 8.4 μM (PGD2 IC50 = 18.6 nM). 17-Phenyl-18,19,20-trinor-PGD2 is a weak agonist of cyclic AMP accumulation[1].

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17-Phenyl-ω-trinor-PGE2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17-Phenyl-ω-trinor-PGE2 is a PGE2 (HY-101952) analog, which is an agonist for EP1 and EP3 receptor. 17-Phenyl-ω-trinor-PGE2 inhibits the PAF-induced aggregation of human platelet-rich plasma (PRP) and Cicaprost (HY-19583) induced Cyclic AMP (HY-B1511) production[1].

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17-trans Prostaglandin E3 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17-trans Prostaglandin E3 is a prostaglandin analog, and stimulates Nurr1-dependent transcriptional activity. 17-trans Prostaglandin E3 can be used for research of condition associated with Nurr1,such as cancer and autoimmune disease[1].

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17(R)-HETE | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17R-HETE is an arachidonic acid metabolite through cytochrome P-450 pathways. 17R-HETE exhibits efficacy in inducing cardic hypertrophy with less efficiency with compared to 17S-HETE[1][2].

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17(R)-Resolvin D1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17R-Resolvin D1 (17R-RvD1; AT-RvD1) is an aspirin-triggered epimer of Resolvin D1, which exhibits anti-inflammatory activity in mice and human PMNs cells[1]. 17R-Resolvin D1 specificially inhibits TRPV3 with an IC50 of 398 nM and exhibits peripheral anti-nociceptive efficacy[2].

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17(S)-HETE | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17S-HETE is arachidonic acid metabolite through cytochrome P-450 pathways. 17S-HETE serves as allosteric activator of the cytochrome P450 1B1 and inhibitor of ATPase, induces cardic hypertrophy[1][2].

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17(S)-HpDHA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17(S)-HpDHA is the main 15-Lipoxygenase (LOX) isoenzyme: h15-LOX-1 and h15-LOX-2 and docosahexaenoic acid (DHA). product. 17(S)-HpDHA negatively regulates epoxide synthesis via allosteric regulation. 17(S)-HpDHA also inhibits platelet aggregation with an EC50 of approximately 1 μM[1].

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17β-Hydroxywortmannin | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

17β-Hydroxywortmannin (Wortmannin-17β-ol) is an orally active inhibitor for phosphatidylinositol-3-kinase (PI-3-kinase) with an IC50 of 0.5 nM, suppresses the osteoclast resorption with an IC50 of 10 nM[1]. 17β-Hydroxywortmannin exhibits antitumor activity[2].

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18-Crown-6-ether | MedChemExpress (MCE) 100 g  | 99.6%

MedChem Express

18-Crown-6-ether (18C6; 1,4,7,10,13,16-Hexaoxacyclooctadecane) is an organic compound that can be used to prepare stable microcapsule responsive layers for further assembly into bilayer microcapsules. For example, 18-Crown-6-ether is used to prepare the response layer and is coated with a G-quadruplex cross-linked hydrogel layer stabilized by K+; when Mg2+ ions are present, 18-Crown-6-ether and K+ ions can […]

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18-HETE | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

18-HETE (compound 3) is a monooxygenase metabolite of cytochrome P450 (CYP450).18- HETE consists of arachidonic acid bearing a hydroxy substituent at position 18[1].

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