MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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α-Synuclein (61-95) (human) TFA | MedChemExpress (MCE) 100 μg  | ≥98.0%

MedChem Express

α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].

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α-Synuclein (61-95) (human) TFA | MedChemExpress (MCE) 500 μg  | ≥98.0%

MedChem Express

α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].

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α-Synuclein (61-95) (human) TFA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

α-Synuclein (61-95) (human) TFA is the hydrophobic core region of α-synuclein, and induces neuronal cell death. α-Synuclein (61-95) (human) TFA can be used for research of neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD)[1][2].

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α-Synuclein inhibitor 13 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

α-Synuclein inhibitor 13 is an inhibitor of α-synuclein (α-Syn). α-Synuclein inhibitor 13 inhibits the aggregation of α-Syn proteins and is able to break down formed fibers. It is mainly used in Parkinson’s disease research[1].

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α-Terpineol-d6 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

α-Terpineol-d6 is deuterated labeled Pulegone (HY-N1500). Pulegone, the major chemical constituent of Nepeta catariaessential oil which is an aromatic herb, is one of avian repellents[1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and […]

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α2C adrenoceptor agonist 1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

α2C adrenoceptor agonist 1 (Compound A) is an orally active, highly selective, and non-central nervous system penetrating agonist for the α2C-adrenoceptor, with EC50 and Ki values of 108 nM and 12 nM, respectively. α2C adrenoceptor agonist 1 can be used in the study of nasal congestion[1].

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α7 nAChR Modulator-3 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

α7 nAChR modulator-3 (Compound 6p) is a α7 nAChR positive allosteric Modulator with a IC50 value of 1.3 μM. α7 nAChR Modulator-3 can be used to inhibit auditory gating defects in a mouse schizophrenic model[1].

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αvβ5 integrin-IN-2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

αvβ5 integrin-IN-2 (Cpd_AV2) is an αvβ5 integrin inhibitor that disrupts the stability of integrin heterodimers. αvβ5 integrin-IN-2 targets the β-propeller central pocket of ITGAV (integrin αV). αvβ5 integrin-IN-2 induces cellular apoptosis[1].

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αvβ5 integrin-IN-2 | MedChemExpress (MCE) 5 mg  | ≥98.0%

MedChem Express

αvβ5 integrin-IN-2 (Cpd_AV2) is an αvβ5 integrin inhibitor that disrupts the stability of integrin heterodimers. αvβ5 integrin-IN-2 targets the β-propeller central pocket of ITGAV (integrin αV). αvβ5 integrin-IN-2 induces cellular apoptosis[1].

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αvβ5 integrin-IN-2 | MedChemExpress (MCE) 10 mg  | ≥98.0%

MedChem Express

αvβ5 integrin-IN-2 (Cpd_AV2) is an αvβ5 integrin inhibitor that disrupts the stability of integrin heterodimers. αvβ5 integrin-IN-2 targets the β-propeller central pocket of ITGAV (integrin αV). αvβ5 integrin-IN-2 induces cellular apoptosis[1].

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β-Ala-Lys(AMCA) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β-Ala-Lys(AMCA) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely […]

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β-AR antagonist 2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β-AR antagonist 2 (compound 43) is an antagonist of β-AR (IC50: 0.17 μM). β-AR-IN-1 inhibits the growth of mouse A549 xenograft tumors and shows cardioprotective efficacy against DOX-induced HF in C57 mice[1].

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β-Cedrene | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β-Cedrene ((+)-β-Cedrene) is a sesquiterpene compound that can be isolated from Centaurea kotschyi var. kotschyi and Centaurea kotschyi var. decumbens, exhibiting antibacterial, anti-inflammatory, antispasmodic, tonic, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is also a potent competitive inhibitor of the CYP2B6-mediatedbupropion hydroxylase, with a Ki value of 1.6 μM[1][2].

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β-Cyfluthrin (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β-Cyfluthrin (Standard) is the analytical standard of β-Cyfluthrin. This product is intended for research and analytical applications. β-Cyfluthrin (beta-Cyfluthrin) is a type II synthetic pyrethroid and also an active ingredient of many insecticide products used for pestsin agriculture. β-Cyfluthrin is a neurotoxicant and affects calcium concentration in nervous tissue by inhibiting Ca2+ ATPase involved in […]

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β-Gal-NONOate | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Beta-gal-nonoate is a β-galactosidase dependent nitric oxide (NO) donor that releases NO once activated by β-galactosidase. β-Gal-NONOate has bactericidal activity and can be used as a bactericide [1].

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β-Glucuronidase responsive conjugate 1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β-Glucuronidase responsive conjugate 1 (compound 3) is a well-balanced photosensitizer which has photodynamic activity. β-Glucuronidase responsive conjugate 1 inhibits T-24 cell viability and growth with an IC50 of 0.2 μM. β-Glucuronidase responsive conjugate 1 can used to study bladder cancers[1].

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β2AR agonist 4 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

β2AR agonist 4 (compound A19) is a potent and selective β2-Adrenoceptor agonist with an EC50 of 3.7 pM. β2AR agonist 4 suppresses the inflammatory cytokines and leukocytes upregulation and improves lung function in COPD rat model[1].

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γ-(6-Aminohexyl)-ATP-biotin | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

γ-(6-Aminohexyl)-ATP-biotin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely […]

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γ-[(6-Aminohexyl)-imido]-ATP-biotin | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

γ-[(6-Aminohexyl)-imido]-ATP-biotin is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely […]

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γ-Glutamyl-β-naphthylamide | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

γ-Glutamyl-β-naphthylamide is a substrate for γ-glutamine peptidase. γ-Glutamyl-β-naphthylamide is specifically recognized and the peptide chain is cleaved. γ-Glutamyl-β-naphthylamide can be used to distinguish between gonococci and meningococci[1].

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γ-Glutamylvaline | MedChemExpress (MCE) 1 mg  | 99.7%

MedChem Express

γ-Glutamylvaline is an activator of CaSR with anti-inflammatory activity. γ-Glutamylvaline inhibits TNF-α-induced proinflammatory cytokine production and increases Wnt5a expression. γ-Glutamylvaline activates calcium-sensing receptor pathways in adipocytes of 3T3-L1 mice and prevents low-grade chronic inflammation[1].

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γ-Glutamylvaline | MedChemExpress (MCE) 5 mg  | 99.7%

MedChem Express

γ-Glutamylvaline is an activator of CaSR with anti-inflammatory activity. γ-Glutamylvaline inhibits TNF-α-induced proinflammatory cytokine production and increases Wnt5a expression. γ-Glutamylvaline activates calcium-sensing receptor pathways in adipocytes of 3T3-L1 mice and prevents low-grade chronic inflammation[1].

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γ-Glutamylvaline | MedChemExpress (MCE) 10 mg  | 99.7%

MedChem Express

γ-Glutamylvaline is an activator of CaSR with anti-inflammatory activity. γ-Glutamylvaline inhibits TNF-α-induced proinflammatory cytokine production and increases Wnt5a expression. γ-Glutamylvaline activates calcium-sensing receptor pathways in adipocytes of 3T3-L1 mice and prevents low-grade chronic inflammation[1].

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γ-Terpinene-d3 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

γ-Terpinene-d3 is deuterated labeled Cinnamyl Alcohol (HY-Y0078). Cinnamyl Alcohol is an active component from chestnut flower, inhibits increased PPARγ expression, with anti-obesity activity[1].

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Δ7(Z)-C14-HSL | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Δ7(Z)-C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7(Z)-C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes[1].

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µ-Conotoxin KIIIA TFA | MedChemExpress (MCE) 1 mg  | 99.2%

MedChem Express

μ-Conotoxin KIIIA TFA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2). μ-Conotoxin KIIIA TFA can be used for research of pain[1][2].

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µ-Conotoxin KIIIA TFA | MedChemExpress (MCE) 5 mg  | 99.2%

MedChem Express

μ-Conotoxin KIIIA TFA is an analgesic μ-conotoxin that can be isolated from Conus kinoshitai. μ-Conotoxin KIIIA blocks mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2). μ-Conotoxin KIIIA TFA can be used for research of pain[1][2].

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ω-3 Arachidonic acid | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

ω-3 Arachidonic acid is a poly fatty acid that is essential for growth and development in infants. ω-3 Arachidonic acid inhibits arachidenol-CoA synthetase with Ki values of 14 µM. It also inhibited arachidenol-CoA synthetase of calf brain extract with IC50 values of about 5 µM[1][2].

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