MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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XL44 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

XL44, an hRpn13 binder, induces hRpn13-dependent apoptosis and also restricts cell viability by a PCLAF-dependent mechanism. XL44 induces ubiquitin-dependent loss of hRpn13Pru and ubiquitin-independent loss of select KEN box containing proteins[1].

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XPC-5462 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

XPC-5462 is a NaV1.6 and NaV1.2 inhibitor with the IC50s of 10.9 nM and 10.3 nM, respectively. XPC-5462 suppresses epileptiform activity in an ex vivo brain slice seizure model[1].

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XPhos | MedChemExpress (MCE) 10 g  | ≥98.0%

MedChem Express

XPhos (2-(Dicyclohexylphosphino)-2′,4′,6′-triisopropylbiphenyl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].

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XPhos | MedChemExpress (MCE) 25 g  | ≥98.0%

MedChem Express

XPhos (2-(Dicyclohexylphosphino)-2′,4′,6′-triisopropylbiphenyl) is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].

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XRD-0394 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

XRD-0394 is a potent and specific dual inhibitor of ATM and DNA-PKcs with oral activity. XRD-0394 significantly enhances tumor cell killing in vitro and in vivo under therapeutic ionizing radiation conditions. In addition, XRD-0394 can potentiate the effects of PARP and topoisomerase I inhibitors in vitro[1].

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XYD190 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

XYD190 (Compound 14g) is an orally active degrader for CBP/p300. XYD190 inhibits CBP/p300 bromodomain with IC50 of 483.7 nM. XYD190 exhibits antitumor activity against acute myeloid leukemia. (Structure: Pink, CBP/p300 ligand 4 (HY-161495); Blue, E3 ligase ligand (HY-14658); Black: linker (HY-161496))[1].

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XYD198 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

XYD198 (Compound 14h) is an orally active degrader for CBP/p300. XYD198 inhibits CBP/p300 bromodomain with IC50 of 213.5 nM. XYD198 exhibits antitumor activity against acute myeloid leukemia. (Structure: Pink, CBP/p300 ligand 4 (HY-161495); Blue, E3 ligase ligand (HY-14658); Black: linker (HY-161499))[1]

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Xylenol blue | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Xylenol blue is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also […]

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Xylometazoline hydrochloride (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Xylometazoline (hydrochloride) (Standard) is the analytical standard of Xylometazoline (hydrochloride). This product is intended for research and analytical applications. Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research[1][2].

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Xylometazoline-d4 hydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Xylometazoline-d4 hydrochloride is deuterated labeled Xylometazoline hydrochloride (HY-B0475). Xylometazoline hydrochloride is an α-adrenergic receptor agonist (Ki=0.05-1.7 μM). Xylometazoline hydrochloride can constrict nasal blood vessels and increase nasal airflow. Xylometazoline hydrochloride can be used in nose stuffiness and runny nose research[1][2].

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Y-29794 tosylate | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Y-29794 tosylate is a selective, orally active inhibitor for non-peptide prolyl endopeptidase (PPCE), with an IC50 of 3 nM and a Ki of 0.95 nM. Y-29794 tosylate enhances the effect of thyrotropin-releasing hormone (TRH) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 tosylate exhibits anticancer activity through inhibition of […]

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