Topoisomerase II inhibitor 18 (Compound IV) is a Quinoxaline derivative, which inhibits topoisomerase II with IC50 of 7.5 μM. Topoisomerase II inhibitor 18 inhibits proliferation, cell cycle at S phase and induces apoptosis in PC-3 cells. Topoisomerase II inhibitor 18 reveals antitumor activity against cancer[1].

Topoisomerase II inhibitor 19 (compound 5h) is a DNA intercalator and topoisomerase II inhibitor (IC50 value of 0.34 μM). Topoisomerase II inhibitor 19 would induce detectable potent damage in ctDNA[1].

Topoisomerase II inhibitor 20 (Compound 3e) is a potent topoisomerase II (Topoisomerase II) inhibitor with an IC50 of 0.98 µM. Topoisomerase II inhibitor 20 induces apoptosis and has broad-spectrum anticancer activity[1].

TOPORS Human Pre-designed siRNA Set A contains three designed siRNAs for TOPORS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Topovale (ARC 111) is a topoisomerase I inhbitor. Topovale is an antitumor agent, and shows low nM cytotoxicity against a panel of cancer cells. Topovale induces reversible topoisomerase I (TOP1) cleavage complexes in tumor cells[1].

TOR1A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOR1AIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1AIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOR1AIP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TOR1AIP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOR3A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOR4A Human Pre-designed siRNA Set A contains three designed siRNAs for TOR4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Torbafylline is a PDE inhibitor. Torbafylline mitigates protein breakdown in rat skeletal muscle following burns by activating the PDE4/cAMP/EPAC/PI3K/Akt signaling pathway. Torbafylline suppresses the increased ubiquitin-proteasome-dependent protein degradation observed in the skeletal muscles of rats susceptible to cancer and sepsis[1].

Tos-Pro-OH is a proline derivative[1].

Tos-Pro-OH is a proline derivative[1].

TOTO-3 (TOTO 3) is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are […]

TOX Human Pre-designed siRNA Set A contains three designed siRNAs for TOX gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOX2 Human Pre-designed siRNA Set A contains three designed siRNAs for TOX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOX3 Human Pre-designed siRNA Set A contains three designed siRNAs for TOX3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TOX4 Human Pre-designed siRNA Set A contains three designed siRNAs for TOX4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP receptor antagonist-1 (compound 7m) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 9.46 μM for TPa and 8.49 μM for TPb, respectively. TP receptor antagonist-1 can be used for the research of cardiovascular disease[1].

TP receptor antagonist-2 (example 7n) is a thromboxane A2 receptor (TP receptor) antagonist, with IC50 values of 5.64 and 5.27 μM for TPα and TPβ, respectively. TP receptor antagonist-2 inhibits platelet aggregation[1].

TP-2, a caltrop-like multicationic small molecule, is an antidote that can completely neutralize both unfractionated heparin (UFH) and low-molecular-weight heparins (LMWHs). TP-2 is not only superior to protamine, has higher neutralization activity, but is also biocompatible[1].

TP53 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Tp53 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tp53 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53AIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53AIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53BP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53BP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53BP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53BP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53I11 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53I13 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53I3 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53INP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53INP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53INP2 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53INP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP53RK Human Pre-designed siRNA Set A contains three designed siRNAs for TP53RK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP63 Human Pre-designed siRNA Set A contains three designed siRNAs for TP63 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TP73 Human Pre-designed siRNA Set A contains three designed siRNAs for TP73 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPA-dT is a thymidine analog with a tris[(2-pyridyl)methyl]amine (TPA) group. TPA-dT can be used to modify siRNAs. The TPA-modified siRNAs remain functionally inactive and is incapable of silencing gene expression until the TPA moiety is removed upon exposure to Cu(I)[1].

TPA-NAC is a nonfluorogenic prodrug by introducing N-acetyl-L-cysteine (NAC) into a conjugated acceptor skeleton. TPA-NAC is capable of fluorogenic selective labeling of HSA[1].

TPBG Human Pre-designed siRNA Set A contains three designed siRNAs for TPBG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPCN1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPCN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPCN2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPCN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPD52 Human Pre-designed siRNA Set A contains three designed siRNAs for TPD52 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPD52L1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPD52L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPD52L2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPD52L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPEG-P is an enzyme-activated intramolecular hydrogen bond (IMHB) enhanced probe, developed for ALP detection in cells and mice models of DILI[1].

TPGS2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPGS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPH1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPH1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPH2 Human Pre-designed siRNA Set A contains three designed siRNAs for TPH2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPI1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TPK1 Human Pre-designed siRNA Set A contains three designed siRNAs for TPK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.