MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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T-0509 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T-0509 ((-)-T-0509) is a selective full agonist of the β1 receptor. T-0509 activates the cAMP signaling pathway through the β1 receptor and enhances myocardial contractility[1].

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T-1-PMPA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T-1-PMPA is a potent EGFR inhibitor with apoptotic properties. T-1-PMPA effectively inhibits EGFRWT and EGFR790m, with IC50 values of 86 nM and 561.73 nM, respectively[1].

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T-518 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T-518 is an orally active, selective, and blood-brain barrier permeable HDAC6 inhibitor with an IC50 value of 36 nM for human HDAC6. T-581 can be used in research on tauopathy[1].

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T-Cadinol | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T-Cadinol is a sesquiterpene isolated from C. sylvestris that exhibits anti-Trypanosoma cruzi activity, with IC50 values of 18.2 μM and 15.8 μM against trypomastigote and amastigote forms, respectively. T-Cadinol can induce mitochondrial damage in parasites, leading to membrane hyperpolarization and decreased levels of reactive oxygen species. T-Cadinol can be used for the research of Chagas […]

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T100-Mut | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T100-Mut is a cell-permeable peptide whose N-terminus is conjugated with a myristoylated group, allowing it to penetrate and localize to the intracellular side of the plasma membrane, thus mimicking the topology of Tmem100-3Q. T100-Mut can alleviate TRPA1-mediated pain[1].

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T3SS-IN-4 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice[1].

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T3SS-IN-5 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T3SS-IN-5 (Compound F9) is a specific inhibitor of the type III secretion system (T3SS). T3SS-IN-5 reduces bacterial pathogenicity without affecting bacterial viability by inhibiting the expression of genes associated with T3SS[1].

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T4-BSA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

T4-BSA is one of protein/peptide and small molecule drug conjugates (PDCs), consisting of T4 (HY-18341) and BSA. PCDs are promising targeted therapeutics with better cell permeability and drug selectivity than antibody-drug conjugates (ADCs). PDCs have been widely used in research on cancer, COVID-19, and metabolic diseases[1].

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TAAR1 agonist 1 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

TAAR1 agonist 1 (compound 6E) is a potent TAAR1 agonist with a potent TAAR1-Gs/Gq dual-pathway activation property. TAAR1 agonist 1 significantly alleviates MK-801-induced schizophrenia-like cognitive phenotypes[1].

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