MedChem Express

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MedChemExpress has an experienced team of custom synthesis chemists, led by an impressive group of Ph.D.'s. With this team, we have the capability of supporting all kinds of chemistry projects of multiple step syntheses of complex labeled molecules, including metabolites and steroids. Following scientific and technological innovation, challenging traditional thinking, MedChemExpress has always been committed to develop quality products that exceed international standards on cost and reliability, to create the most advanced synthetic route. With high experiences in preparing a large numbers of different biologically active molecules, we provide rapid synthesis of new products. That is why we can consistently deliver your custom synthesis compounds faster than any other company.

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Amiodarone hydrochloride (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amiodarone (hydrochloride) (Standard) is the analytical standard of Amiodarone (hydrochloride). This product is intended for research and analytical applications. Amiodarone hydrochloride, a benzofuran-based Class III antiarrhythmic agent, inhibits WT outwardIhERG tails with an IC50 of ∼45 nM[1]. Amiodarone hydrochloride induces cell proliferation and myofibroblast differentiation via ERK1/2 and p38 MAPK signaling in fibroblasts[2]. Amiodarone hydrochloride […]

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Amlodipine besylate (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amlodipine (besylate) (Standard) is the analytical standard of Amlodipine (besylate). This product is intended for research and analytical applications. Amlodipine besylate (Amlodipine benzenesulfonate), an antianginal agent and an orally active dihydropyridine calcium channel blocker, works by blocking the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine besylate can be used for […]

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Amlodipine-d9 maleate | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amlodipine-d9 maleate is deuterated labeled Amlodipine maleate (HY-B0317A). Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate blocks the voltage-dependent L-type calcium channels, thereby inhibiting the initial influx of calcium. Amlodipine maleate can be used for the research of high blood pressure and cancer[1][2][3].

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Amodiaquine-d10 hydrochloride | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect[1][2][3][4].

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Amorfrutin B | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amorfrutin B is a highly potent natural peroxisome proliferation-activated receptor γ (PPARγ) agonist with oral activity with Ki values of 19 nM and EC50 values of 73 nM, respectively. Amorfrutin B has hypoglycemic and neuroprotective activities[1][2].

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Amoxapine (Standard) | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amoxapine (Standard) is the analytical standard of Amoxapine. This product is intended for research and analytical applications. Amoxapine is a tetracyclic antidepressant of the dibenzoxazepine family, although it is generally classified as a secondary amine tricyclic antidepressant.

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AMOZ/BSA | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

AMOZ/BSA is one of protein/peptide and small molecule drug conjugates (PDCs), consisting of AMOZ (HY-131146) and BSA. PCDs are promising targeted therapeutics with better cell permeability and drug selectivity than antibody-drug conjugates (ADCs). PDCs have been widely used in research on cancer, COVID-19, and metabolic diseases[1].

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AMPK-IN-5 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

AMPK-IN-5 (compound 7m) is a Osthole (HY-N0054) derivative, and blocks MAPK signal transduction by inhibiting the phosphorylation of JNK and p38, thereby inhibiting the release of inflammatory cytokines. AMPK-IN-5 reduce DSS-induced ulcerative colitis and LPS (HY-D1056)-induced acute lung injury[1].

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Amyloid precursor C-terminal peptide | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Amyloid precursor C-terminal peptide is cleaved from the C-terminus of Amyloid Precursor Protein (APP). Amyloid precursor C-terminal peptide accumulation causes mitochondrial morphology alteration and basal mitophagy failure, which indicates that amyloid precursor protein C-terminal peptide may correspond to an etiological trigger of Alzheimer’s disease (AD) pathology[1].

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Anagrelide-13C2,15N,d2 | MedChemExpress (MCE) 1 mg  | ≥98.0%

MedChem Express

Anagrelide-13C2,15N,d2 is 15N and deuterated labeled Anagrelide (HY-B0523). Anagrelide is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36?nM). Anagrelide, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide inhibits bone marrow megakaryocytopoiesis. Anagrelide decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide is a platelet-lowering agent and […]

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