PI3K-IN-18 (Compound 1) is a PI3K inhibitor, and can also effectively inhibit the homologous enzymemTOR. The IC50 values of PI3K-IN-18 for mTOR and PI3K-α were 49 nM and 41 nM, respectively[1].

PI3K-IN-52 (compound cis 6g) is a potent inhibitor of PI3K, with IC50 of 0.23 μM in HGC-27 cells. PI3K-IN-52 plays an important role in cancer research[1].

PI3K/Akt/mTOR-IN-4 (compound 4r) is a potent PI3K/Akt/mTOR and tubulin polymerization inhibitor. PI3K/Akt/mTOR-IN-4 induce apoptosis and cell cycle arrest at G2/M phase. PI3K/Akt/mTOR-IN-4 decreases the expression of p-PI3K, p-Akt, and p-mTOR, β-tubulin[1].

PI3Kα-IN-1 is a PI3Kα inhibitor (IC50 < 0.5 nM), and also inhibits mTOR (IC50: 104 nM)[1].

PI3Kα-IN-19 (Compound 1) is a PI3Kα inhibitor with a targeted binding site at the p110α catalytic subunit. PI3Kα is one of the most common dysregulated kinases used in cancer research[1].

PI3Kα-IN-20 (compound 2) is a selective PI3Kα inhibitor[1].

PI3Kα-IN-22 (Compound 17) is an orally active, potent and selective inhibitor of PI3KαH1047R, with an IC50 of 1 nM for pAKT T47D AlphaLISA. PI3Kα-IN-22 can induce tumor regressions in the HCC1954 tumor model in mice[1].

PI3Kδ-IN-20 (compound ( S )-36) is a potent inhibitor of PI3Kδ, with the IC50 of 6.4 nM. PI3Kδ-IN-20 has oral bioactivity. PI3Kδ-IN-20 shows significant suppression of cell proliferation and remarkable induction of apoptosis both in vitro and in vivo[1].

PI4K2A Human Pre-designed siRNA Set A contains three designed siRNAs for PI4K2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PI4K2B Human Pre-designed siRNA Set A contains three designed siRNAs for PI4K2B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PI4KA Human Pre-designed siRNA Set A contains three designed siRNAs for PI4KA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pi4ka Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pi4ka gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pi4ka Rat Pre-designed siRNA Set A contains three designed siRNAs for Pi4ka gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PI4KB Human Pre-designed siRNA Set A contains three designed siRNAs for PI4KB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pi4kb Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pi4kb gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pi4kb Rat Pre-designed siRNA Set A contains three designed siRNAs for Pi4kb gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIANP Human Pre-designed siRNA Set A contains three designed siRNAs for PIANP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIAS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIAS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIAS2 Human Pre-designed siRNA Set A contains three designed siRNAs for PIAS2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIAS3 Human Pre-designed siRNA Set A contains three designed siRNAs for PIAS3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIAS4 Human Pre-designed siRNA Set A contains three designed siRNAs for PIAS4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIBF1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIBF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PICALM Human Pre-designed siRNA Set A contains three designed siRNAs for PICALM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PICK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PICK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Picolinamide (Standard) is the analytical standard of Picolinamide. This product is intended for research and analytical applications. Picolinamide (2-Picolinamide) is an inhibitor of Poly(ADP-ribose) synthetase of nuclei from rat pancreatic islet cells[1][3].

PID-9 is a P-glycoprotein inhibitor. PID-9 has multidrug resistance (MDR) reversal activity (IC50 = 0.1338 μM) and low toxicity. PID-9 inhibits the transport function of P-gp without downregulating P-gp expression[1].

PID1 Human Pre-designed siRNA Set A contains three designed siRNAs for PID1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIDD1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIDD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIERCE1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIERCE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIEZO1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIEZO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIEZO2 Human Pre-designed siRNA Set A contains three designed siRNAs for PIEZO2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIF1 Human Pre-designed siRNA Set A contains three designed siRNAs for PIF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIFO Human Pre-designed siRNA Set A contains three designed siRNAs for PIFO gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pig Insulin-PE is a biochemical reagent that can be used as a biological material or organic compound for life science related research[1].

PIGA Human Pre-designed siRNA Set A contains three designed siRNAs for PIGA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGB Human Pre-designed siRNA Set A contains three designed siRNAs for PIGB gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGC Human Pre-designed siRNA Set A contains three designed siRNAs for PIGC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGF Human Pre-designed siRNA Set A contains three designed siRNAs for PIGF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGG Human Pre-designed siRNA Set A contains three designed siRNAs for PIGG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGH Human Pre-designed siRNA Set A contains three designed siRNAs for PIGH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGK Human Pre-designed siRNA Set A contains three designed siRNAs for PIGK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGL Human Pre-designed siRNA Set A contains three designed siRNAs for PIGL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PIGM Human Pre-designed siRNA Set A contains three designed siRNAs for PIGM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pigment black 32 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are […]

Pigment blue 60 is an excellent paint and ceramic stain.