PD-L1-IN-4 (Compound X18) is an orally active PD-L1 inhibitor that exhibits remarkable inhibitory activity against the PD-1/PD-L1 interaction (IC50 = 1.3 nM) and enhances PD-L1 inhibitory effect on T cells (EC50 = 152.8 nM). PD-L1-IN-4 can be used for the research of cancer[1].

PD-L1-IN-5 (X22) is an orally active PD-L1 inhibitor, with the IC50 value of 785.6 nM. PD-L1-IN-5 has anti-tumor activity in vivo[1].

PD-L1-IN-6 (Compound 16) is an orally active inhibitor for PD-L1 expression in neutrophil by targeting STAT3 with KD of 90.5 nmol/L. PD-L1-IN-6 promotes neutrophil-mediated antifungal immunoresponse[1].

PD-L1/PD-1-IN-1 (compound 8j) is a potent inhibitor of PD-L1/PD interaction, with IC50 ＜ 1 nM. PD-L1/PD-1-IN-1 plays an important role in anti-tumor research[1].

PDAP1 Human Pre-designed siRNA Set A contains three designed siRNAs for PDAP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDC Human Pre-designed siRNA Set A contains three designed siRNAs for PDC gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD1 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pdcd1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pdcd1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pdcd1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pdcd1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD10 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD11 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD1LG2 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD1LG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD2 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD4 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD5 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD6 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCD6IP Human Pre-designed siRNA Set A contains three designed siRNAs for PDCD6IP gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCL Human Pre-designed siRNA Set A contains three designed siRNAs for PDCL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCL2 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDCL3 Human Pre-designed siRNA Set A contains three designed siRNAs for PDCL3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDDHV is a calcium absorption inducer and may achieve 45Ca2+ influx by stimulating vanillic acid receptor VR1. PDDHV induces 45Ca2+ uptake (EC50: 70 nM) in rat dorsal root ganglion neurons (expressing native vanilloid receptors) and calcium mobilization (EC50: 125 nM) in VR1-transfected CHO cells. PDDHV also inhibits [3H]-resiniferatoxin (RTX) binding to the dorsal root ganglion […]

PDE-IN-3 (compound 23) is a phosphodiesterase (PDE) inhibitor with an IC50 of 260 μM[1].

PDE1-IN-6 (compound 6c) is a selectivity PDE1 inhibitor with the IC50 of 7.5 nM. PDE1-IN-6 significantly inhibits the proliferation and induced cell apoptosis in Acute myelogenous leukemia cells[1].

PDE1-IN-7 (Compound 13h) is a selective inhibitor of bPDE1 (IC50= 10 nM). PDE1-IN-7 exhibits significant anti-fibrotic effects in a BDL-induced liver fibrosis rat model. PDE1-IN-7 can be used for research in liver fibrosis[1].

PDE10A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE10A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde10a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde10a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde10a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde10a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE10A-IN-3 (Compound 8a) is an inhibitor of phosphodiesterase 10A (PDE10A). PDE10A-IN-3 can be used in schizophrenia research[1].

PDE11A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE11A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde11a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde11a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde11a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde11a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE12 Human Pre-designed siRNA Set A contains three designed siRNAs for PDE12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde12 Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde12 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE1A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde1a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde1a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE1A Rat Pre-designed siRNA Set A contains three designed siRNAs for PDE1A gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE1B Human Pre-designed siRNA Set A contains three designed siRNAs for PDE1B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE1C Human Pre-designed siRNA Set A contains three designed siRNAs for PDE1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE2A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde2a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde2a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde2a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde2a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

PDE3A Human Pre-designed siRNA Set A contains three designed siRNAs for PDE3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde3a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pde3a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pde3a Rat Pre-designed siRNA Set A contains three designed siRNAs for Pde3a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.