MedChem Express
NRG3 Human Pre-designed siRNA Set A contains three designed siRNAs for NRG3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRG4 Human Pre-designed siRNA Set A contains three designed siRNAs for NRG4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRGN Human Pre-designed siRNA Set A contains three designed siRNAs for NRGN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRIP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRIP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRIP2 Human Pre-designed siRNA Set A contains three designed siRNAs for NRIP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRIP3 Human Pre-designed siRNA Set A contains three designed siRNAs for NRIP3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRK Human Pre-designed siRNA Set A contains three designed siRNAs for NRK gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRL Human Pre-designed siRNA Set A contains three designed siRNAs for NRL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRM Human Pre-designed siRNA Set A contains three designed siRNAs for NRM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRN1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRN1L Human Pre-designed siRNA Set A contains three designed siRNAs for NRN1L gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRP2 Human Pre-designed siRNA Set A contains three designed siRNAs for NRP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRPSs-IN-1 (Compound 7) is a cell-penetrating inhibitor of non-ribosomal peptide synthetase (NRPSs). NRPSs-IN-1 K inhibits gramicidin S synthetase A (GrsA) with a Kd value of 16.6 nM[1].
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NRROS Human Pre-designed siRNA Set A contains three designed siRNAs for NRROS gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRTN Human Pre-designed siRNA Set A contains three designed siRNAs for NRTN gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRXN1 Human Pre-designed siRNA Set A contains three designed siRNAs for NRXN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRXN2 Human Pre-designed siRNA Set A contains three designed siRNAs for NRXN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NRXN3 Human Pre-designed siRNA Set A contains three designed siRNAs for NRXN3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSA2 Human Pre-designed siRNA Set A contains three designed siRNAs for NSA2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSCLC-IN-1 (Compound A10-2) induces mitophagy and ferroptosis through targeting transmembrane BAX inhibitor motif containing 6 (TMBIM6). NSCLC-IN-1 induces mitochondrial Ca2+ imbalance, leading to mitochondrial damage. NSCLC-IN-1 reduces intracellular glutathione (GSH), increases the accumulation of lipid peroxides (LPO) and malondialdehyde (MDA) content. NSCLC-IN-1 is a potent anti-NSCLC agent[1].
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NSD-IN-3 (compound 3) is a potent nuclear receptor binding SET domain (NSD) inhibitor. NSD-IN-3 inhibits NSD2-SET and NSD3-SET with IC50 values of 0.81 μM and 0.84 μM, respectively. NSD-IN-3 inhibits histone H3K36 dimethylation and decreases the expression of NSDs-targeted genes in non-small cell lung cancer cells. NSD-IN-3 induces s-phase cell cycle arrest and apoptosis[1].
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NSD1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSD1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSD2 Human Pre-designed siRNA Set A contains three designed siRNAs for NSD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSD3 Human Pre-designed siRNA Set A contains three designed siRNAs for NSD3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSDHL Human Pre-designed siRNA Set A contains three designed siRNAs for NSDHL gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSF Human Pre-designed siRNA Set A contains three designed siRNAs for NSF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSFL1C Human Pre-designed siRNA Set A contains three designed siRNAs for NSFL1C gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSG1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSG1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSG2 Human Pre-designed siRNA Set A contains three designed siRNAs for NSG2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSL1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSMAF Human Pre-designed siRNA Set A contains three designed siRNAs for NSMAF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSMCE1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSMCE1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSMCE2 Human Pre-designed siRNA Set A contains three designed siRNAs for NSMCE2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NSMF Human Pre-designed siRNA Set A contains three designed siRNAs for NSMF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Nsp12-IN-1is a nucleoside analogue. Nsp12-IN-1 can block the synthesis of viral RNA and inhibit viral replication. Nsp12-IN-1 can be used in the study of pan-coronavirus[1].
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NSRP1 Human Pre-designed siRNA Set A contains three designed siRNAs for NSRP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1].
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NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1].
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NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1].
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NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1].
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MedChem Express
NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation. NST-628 also binds RAF and prevents the formation of BRAF-CRAF and BRAF-ARAF heterodimers, effectively inhibiting the RAS-MAPK pathway. NST-628 inhibits RAS- and RAF-driven cancers and demonstrated potent inhibition in mutant KRAS, NRAS, BRAF class II/III, and NF1-mutant tumors[1].
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